Cathepsin G degradation of phospholipid transfer protein (PLTP) augments pulmonary inflammation

FASEB Journal

Volumn 28, Issue 5, 2014, Pages 2318-2331

  Brehm, Anthony ^a   Geraghty, Patrick ^a   Campos, Michael ^b   Garcia Arcos, Itsaso ^c   Dabo, Abdoulaye Jules ^a   Gaffney, Adam ^d   Eden, Edward ^a   Jiang, Xian Cheng ^e   D'Armiento, Jeanine ^c   Foronjy, Robert ^a  

^a ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Lipopolysaccharide; Lung; Protease; Signaling

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; CATHEPSIN G; GAMMA INTERFERON; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPID TRANSFER PROTEIN; RECOMBINANT PROTEIN; SERINE PROTEINASE; SMALL INTERFERING RNA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; INTRACELLULAR SIGNALING; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION;

LIPOPOLYSACCHARIDE; LUNG; PROTEASE; SIGNALING;

AGED; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CATHEPSIN G; CELLS, CULTURED; EPITHELIAL CELLS; FEMALE; HUMANS; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; LUNG; MALE; MATRIX METALLOPROTEINASE 9; MICE; MIDDLE AGED; NF-KAPPA B; PHOSPHOLIPID TRANSFER PROTEINS; PNEUMONIA; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMOKING;

EID: 84901049772     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-246843     Document Type: Article

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