Inhibiting tyrosine phosphorylation of protein kinase Cδ (PKCδ) protects the salivary gland from radiation damage

Journal of Biological Chemistry

Volumn 289, Issue 15, 2014, Pages 10900-10908

  Wie, Sten M ^a,b   Adwan, Tariq S ^b   DeGregori, James ^c   Anderson, Steven M ^d   Reyland, Mary E ^a,b  

^a University of Colorado Anschutz Medical Campus Program in Structural Biology and Biochemistry   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c Departments of Biochemistry and Molecular Genetics   (United States)

^d Western Campus of Tufts University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; ENZYME INHIBITION; HISTOLOGY; IRRADIATION; PHOSPHORYLATION; RADIATION DAMAGE; RADIOTHERAPY; TISSUE;

APOPTOTIC STIMULI; HEAD-AND-NECK CANCER; NUCLEAR ACCUMULATION; PROTEIN KINASE C; RADIATION-INDUCED APOPTOSIS; TYROSINE KINASE; TYROSINE KINASE INHIBITOR; TYROSINE PHOSPHORYLATION;

AMINO ACIDS;

ABELSON KINASE; CASPASE 3; DASATINIB; ETOPOSIDE; IMATINIB; KARYOPHERIN ALPHA; PROTEIN KINASE C DELTA; PROTEIN KINASE P60; SHORT HAIRPIN RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RADIATION INJURY; SALIVARY GLAND;

APOPTOSIS; NONRECEPTOR TYROSINE KINASE; PROTEIN KINASE C (PKC); RADIATION BIOLOGY; SALIVARY GLAND;

ACTIVE TRANSPORT, CELL NUCLEUS; ALPHA KARYOPHERINS; ANIMALS; APOPTOSIS; CELL NUCLEUS; DNA DAMAGE; FEMALE; HEK293 CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE C-DELTA; PROTO-ONCOGENE PROTEINS C-ABL; PYRIMIDINES; SALIVARY GLANDS; SRC-FAMILY KINASES; THIAZOLES; TYROSINE;

EID: 84898632704     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.551366     Document Type: Article

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