Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells

Arthritis Research and Therapy

Volumn 17, Issue 1, 2015, Pages

  Miyazaki, Shingo ^a   Kakutani, Kenichiro ^a   Yurube, Takashi ^a   Maeno, Koichiro ^a   Takada, Toru ^a   Zhang, Zhongying ^a   Kurakawa, Takuto ^a   Terashima, Yoshiki ^a   Ito, Masaaki ^a   Ueha, Takeshi ^a   Matsushita, Takehiko ^a   Kuroda, Ryosuke ^a   Kurosaka, Masahiro ^a   Nishida, Kotaro ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; CASPASE 3; DANSYLCADAVERINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P62; RECOMBINANT HUMAN SIRTUIN 1; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; 3-METHYLADENINE; ADENINE; CASPASE; CULTURE MEDIUM; SIRT1 PROTEIN, HUMAN; SIRTUIN 1;

AGED; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL COUNT; CELL DEGENERATION; CELL ISOLATION; CELL PROTECTION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTERVERTEBRAL DISK DEGENERATION; LIGHT CHAIN; MALE; NUCLEUS PULPOSUS; PROTEIN CLEAVAGE; SCHOOL CHILD; SIGNAL TRANSDUCTION; VERY ELDERLY; WESTERN BLOTTING; ADOLESCENT; ADULT; ANALOGS AND DERIVATIVES; ANIMAL; BOVINE; CELL CULTURE; CHEMISTRY; CULTURE MEDIUM; DRUG EFFECTS; FETUS BLOOD; GENETICS; INTERVERTEBRAL DISK; METABOLISM; MIDDLE AGED; MITOCHONDRION; PATHOLOGY; PHARMACOLOGY;

ADENINE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CASPASES; CATTLE; CELLS, CULTURED; CHILD; CULTURE MEDIA; FEMALE; FETAL BLOOD; HUMANS; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; MALE; MIDDLE AGED; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT PROTEINS; SIRTUIN 1;

EID: 84941637401     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-015-0763-6     Document Type: Article

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