Acute and subchronic oral toxicity studies in rats with nanoscale and pigment grade titanium dioxide particles

Food and Chemical Toxicology

Volumn 84, Issue , 2015, Pages 208-224

  Warheit, D B ^a   Brown, S C ^a   Donner, E M ^b  

^a CHEMOURS COMPANY   (United States)

^b DUPONT COMPANY   (United States)

Author keywords

Guideline studies; Nanoparticles; Oral exposure; Particles; Subchronic toxicity testing; Titanium dioxide

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CHOLESTEROL; CREATININE; GLUCOSE; IDITOL DEHYDROGENASE; TITANIUM DIOXIDE NANOPARTICLE; TRIACYLGLYCEROL; FOOD ADDITIVE; METAL NANOPARTICLE; TITANIUM; TITANIUM DIOXIDE;

ACUTE TOXICITY; ADSORPTION; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CHRONIC TOXICITY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DENSITY GRADIENT; DESORPTION; DISPERSION; ENZYME BLOOD LEVEL; ESOPHAGUS INJURY; ESOPHAGUS PERFORATION; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; LD50; MALE; MOLECULAR WEIGHT; NONHUMAN; ORAL TOXICITY; PARTICLE SIZE; RAT; TOXICITY; TRIACYLGLYCEROL BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL; YOUNG ADULT; ZETA POTENTIAL; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORAL DRUG ADMINISTRATION; PHYSICAL CHEMISTRY; PRACTICE GUIDELINE; SPRAGUE DAWLEY RAT; STANDARDS; SURFACE PROPERTY; TOXICITY TESTING; UNITED STATES; VALIDATION STUDY;

ADMINISTRATION, ORAL; ANIMALS; FEMALE; FOOD ADDITIVES; GUIDELINES AS TOPIC; MALE; METAL NANOPARTICLES; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PARTICLE SIZE; PHYSICOCHEMICAL PHENOMENA; RATS, SPRAGUE-DAWLEY; SURFACE PROPERTIES; TITANIUM; TOXICITY TESTS, ACUTE; TOXICITY TESTS, SUBCHRONIC; UNITED STATES;

EID: 84941629750     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2015.08.026     Document Type: Article

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