The generation and characterization of novelCol1a1FRT-Cre-ER-T2-FRT and Col1a1FRT-STOP-FRT-Cre-ER-T2 mice for sequential mutagenesis

DMM Disease Models and Mechanisms

Volumn 8, Issue 9, 2015, Pages 1155-1166

  Zhang, Minsi ^a   Kirsch, David G ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Dual recombinase technology; Mouse models; Sequential mutagenesis

Indexed keywords

AFIMOXIFENE; COLLAGEN TYPE 1; COLLAGEN TYPE 1 ALPHA 1; CRE RECOMBINASE; FLP FRT RECOMBINASE; GENOMIC DNA; RECOMBINASE; TAMOXIFEN; UNCLASSIFIED DRUG; COLLAGEN TYPE I, ALPHA 1 CHAIN; DNA POLYMERASE; INTEGRASE;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GENETICS; CANCER MODEL; CANCER THERAPY; CARCINOGENESIS; CONTROLLED STUDY; GENE MUTATION; GENETIC MANIPULATION; HOMOLOGOUS RECOMBINATION; LOXP SITE; MALE; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SOFT TISSUE SARCOMA; ADENOVIRIDAE; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CHEMISTRY; CYTOLOGY; DISEASE MODEL; EMBRYONIC STEM CELL; FEMALE; FLUORESCENCE MICROSCOPY; GENE DELETION; GENETIC ENGINEERING; GENETICS; GENOME; HOMEOSTASIS; MUTATION; PROCEDURES; RETRACTED ARTICLE; TRANSGENIC MOUSE;

ADENOVIRIDAE; ALLELES; ANIMALS; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; DNA NUCLEOTIDYLTRANSFERASES; EMBRYONIC STEM CELLS; FEMALE; GENE DELETION; GENETIC ENGINEERING; GENOME; HOMEOSTASIS; INTEGRASES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MUTAGENESIS; MUTATION; TAMOXIFEN;

EID: 84941559745     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.021204     Document Type: Article

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