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Volumn 42, Issue 10, 2015, Pages 1118-1126

Diet induced obesity in rats reduces NHE3 and Na+/K+-ATPase expression in the kidney

Author keywords

AKT; Na+ K+ ATPase; NHE3; Obesity; Proteinuria

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALBUMIN; PROTEIN KINASE B; SODIUM; SODIUM PROTON EXCHANGE PROTEIN 3; PHOSPHOPROTEIN; SODIUM PROTON EXCHANGE PROTEIN; SODIUM-HYDROGEN EXCHANGER 3;

EID: 84941555901     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/1440-1681.12452     Document Type: Article
Times cited : (11)

References (56)
  • 2
    • 34848850791 scopus 로고    scopus 로고
    • Protein kinase C phosphorylation disrupts Na+/H+ exchanger regulatory factor 1 autoinhibition and promotes cystic fibrosis transmembrane conductance regulator macromolecular assembly
    • Li J, Poulikakos PI, Dai Z, Testa JR, Callaway DJ, Bu Z. Protein kinase C phosphorylation disrupts Na+/H+ exchanger regulatory factor 1 autoinhibition and promotes cystic fibrosis transmembrane conductance regulator macromolecular assembly. J. Biol. Chem. 2007; 282: 27086-99.
    • (2007) J. Biol. Chem. , vol.282 , pp. 27086-27099
    • Li, J.1    Poulikakos, P.I.2    Dai, Z.3    Testa, J.R.4    Callaway, D.J.5    Bu, Z.6
  • 3
    • 41449110029 scopus 로고    scopus 로고
    • Renal injury in the extremely obese patients with normal renal function
    • Serra A, Romero R, Lopez D et al. Renal injury in the extremely obese patients with normal renal function. Kidney Int. 2008; 73: 947-55.
    • (2008) Kidney Int. , vol.73 , pp. 947-955
    • Serra, A.1    Romero, R.2    Lopez, D.3
  • 5
    • 31544451031 scopus 로고    scopus 로고
    • Renal albumin absorption in physiology and pharmacology
    • Birn H, Christensen EI. Renal albumin absorption in physiology and pharmacology. Kidney Int. 2006; 69: 440-9.
    • (2006) Kidney Int. , vol.69 , pp. 440-449
    • Birn, H.1    Christensen, E.I.2
  • 6
    • 84984766757 scopus 로고    scopus 로고
    • Megalin and cubilin: Multifunctional endocytic receptors
    • Christensen EI, Birn H. Megalin and cubilin: Multifunctional endocytic receptors. Nat. Rev. Mol. Cell Biol. 2002; 3: 256-66.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 256-266
    • Christensen, E.I.1    Birn, H.2
  • 7
    • 0035971106 scopus 로고    scopus 로고
    • Active (9.6S) and inactive (21S) oligomers of NHE3 in microdomains of the renal brush border
    • Biemesderfer D, DeGray B, Aronson PS. Active (9.6S) and inactive (21S) oligomers of NHE3 in microdomains of the renal brush border. J. Biol. Chem. 2001; 276: 10161-7.
    • (2001) J. Biol. Chem. , vol.276 , pp. 10161-10167
    • Biemesderfer, D.1    DeGray, B.2    Aronson, P.S.3
  • 8
    • 79951618570 scopus 로고    scopus 로고
    • Na+-H+ exchanger regulatory factor 1 (NHERF1) PDZ scaffold binds an internal binding site in the scavenger receptor megalin
    • Slattery C, Jenkin KA, Lee A et al. Na+-H+ exchanger regulatory factor 1 (NHERF1) PDZ scaffold binds an internal binding site in the scavenger receptor megalin. Cell. Physiol. Biochem. 2011; 27: 171-8.
    • (2011) Cell. Physiol. Biochem. , vol.27 , pp. 171-178
    • Slattery, C.1    Jenkin, K.A.2    Lee, A.3
  • 9
    • 0035940785 scopus 로고    scopus 로고
    • The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat
    • Sanchez JF, Krause JE, Cortright DN. The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat. Neuroscience 2001; 107: 373-81.
    • (2001) Neuroscience , vol.107 , pp. 373-381
    • Sanchez, J.F.1    Krause, J.E.2    Cortright, D.N.3
  • 10
    • 48049112843 scopus 로고    scopus 로고
    • More choices than ever before: Emerging therapies for type 2 diabetes
    • Campbell RK, White JRJ. More choices than ever before: Emerging therapies for type 2 diabetes. Diabetes Educ. 2008; 34: 518-34.
    • (2008) Diabetes Educ. , vol.34 , pp. 518-534
    • Campbell, R.K.1    White, J.R.J.2
  • 11
    • 84859845211 scopus 로고    scopus 로고
    • Generation of urinary albumin fragments does not require proximal tubular uptake
    • Weyer K, Nielsen R, Christensen EI, Birn H. Generation of urinary albumin fragments does not require proximal tubular uptake. J. Am. Soc. Nephrol. 2012; 23: 591-6.
    • (2012) J. Am. Soc. Nephrol. , vol.23 , pp. 591-596
    • Weyer, K.1    Nielsen, R.2    Christensen, E.I.3    Birn, H.4
  • 12
    • 79953162660 scopus 로고    scopus 로고
    • Megalin is downregulated via LPS-TNF-α-ERK1/2 signaling pathway in proximal tubule cells
    • Takeyama A, Sato H, Soma-Nagae T et al. Megalin is downregulated via LPS-TNF-α-ERK1/2 signaling pathway in proximal tubule cells. Biochem. Biophys. Res. Commun. 2011; 407: 108-12.
    • (2011) Biochem. Biophys. Res. Commun. , vol.407 , pp. 108-112
    • Takeyama, A.1    Sato, H.2    Soma-Nagae, T.3
  • 13
    • 28544437241 scopus 로고    scopus 로고
    • Role of megalin, a proximal tubular endocytic receptor, in the pathogenesis of diabetic and metabolic syndrome-related nephropathies: Protein metabolic overload hypothesis
    • Saito A, Takeda T, Hama H et al. Role of megalin, a proximal tubular endocytic receptor, in the pathogenesis of diabetic and metabolic syndrome-related nephropathies: Protein metabolic overload hypothesis. Nephrology 2005; 10: S26-31.
    • (2005) Nephrology , vol.10 , pp. S26-S31
    • Saito, A.1    Takeda, T.2    Hama, H.3
  • 15
    • 84930792541 scopus 로고    scopus 로고
    • Chronic administration of AM251 improves albuminuria and renal tubular structure in obese rats
    • Jenkin KA, O'Keefe L, Simcocks AC et al. Chronic administration of AM251 improves albuminuria and renal tubular structure in obese rats. J. Endocrinol. 2015; 225: 113-24.
    • (2015) J. Endocrinol. , vol.225 , pp. 113-124
    • Jenkin, K.A.1    O'Keefe, L.2    Simcocks, A.C.3
  • 16
    • 79951639177 scopus 로고    scopus 로고
    • Nebivolol attenuates redox-sensitive glomerular and tubular mediated proteinuria in obese rats
    • Habibi J, Hayden MR, Sowers JR et al. Nebivolol attenuates redox-sensitive glomerular and tubular mediated proteinuria in obese rats. Endocrinology 2011; 152: 659-68.
    • (2011) Endocrinology , vol.152 , pp. 659-668
    • Habibi, J.1    Hayden, M.R.2    Sowers, J.R.3
  • 17
    • 84916608391 scopus 로고    scopus 로고
    • Acute leptin exposure reduces megalin expression and upregulates TGFβ1 in cultured renal proximal tubule cells
    • Briffa JF, Grinfeld E, Mathai ML, Poronnik P, McAinch AJ, Hryciw DH. Acute leptin exposure reduces megalin expression and upregulates TGFβ1 in cultured renal proximal tubule cells. Mol. Cell. Endocrinol. 2015; 401: 25-34.
    • (2015) Mol. Cell. Endocrinol. , vol.401 , pp. 25-34
    • Briffa, J.F.1    Grinfeld, E.2    Mathai, M.L.3    Poronnik, P.4    McAinch, A.J.5    Hryciw, D.H.6
  • 18
    • 0036112490 scopus 로고    scopus 로고
    • Dysregulation of renal salt and water transport proteins in diabetic Zucker rats
    • Bickel CA, Knepper MA, Verbalis JG, Ecelbarger CA. Dysregulation of renal salt and water transport proteins in diabetic Zucker rats. Kidney Int. 2002; 61: 2099-110.
    • (2002) Kidney Int. , vol.61 , pp. 2099-2110
    • Bickel, C.A.1    Knepper, M.A.2    Verbalis, J.G.3    Ecelbarger, C.A.4
  • 20
    • 84896804088 scopus 로고    scopus 로고
    • AKT and GSK-3 are necessary for direct ezrin binding to NHE3 as part of a C-terminal stimulatory complex: Role of a novel Ser-rich NHE3 C-terminal motif in NHE3 activity and trafficking
    • Singh V, Lin R, Yang J et al. AKT and GSK-3 are necessary for direct ezrin binding to NHE3 as part of a C-terminal stimulatory complex: Role of a novel Ser-rich NHE3 C-terminal motif in NHE3 activity and trafficking. J. Biol. Chem. 2014; 289: 5449-61.
    • (2014) J. Biol. Chem. , vol.289 , pp. 5449-5461
    • Singh, V.1    Lin, R.2    Yang, J.3
  • 22
    • 32844463192 scopus 로고    scopus 로고
    • Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin
    • Li Z, Rodríguez-Iturbe B, Ni Z, Shahkarami A, Sepassi L, Vaziri ND. Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin. Kidney Int. 2005; 68: 2766-72.
    • (2005) Kidney Int. , vol.68 , pp. 2766-2772
    • Li, Z.1    Rodríguez-Iturbe, B.2    Ni, Z.3    Shahkarami, A.4    Sepassi, L.5    Vaziri, N.D.6
  • 23
    • 77955895472 scopus 로고    scopus 로고
    • Marked association between obesity and glomerular hyperfiltration: A cross-sectional study in an African population
    • Wuerzner G, Pruijm M, Maillard M et al. Marked association between obesity and glomerular hyperfiltration: A cross-sectional study in an African population. Am. J. Kidney Dis. 2010; 56: 303-12.
    • (2010) Am. J. Kidney Dis. , vol.56 , pp. 303-312
    • Wuerzner, G.1    Pruijm, M.2    Maillard, M.3
  • 24
    • 84962587278 scopus 로고    scopus 로고
    • Renal Effects of Chronic Pharmacological Manipulation of CB2 in Rats with Diet Induced Obesity
    • Epub ahead of print
    • Jenkin KA, O'Keefe L, Simcocks AC et al. Renal Effects of Chronic Pharmacological Manipulation of CB2 in Rats with Diet Induced Obesity. Br. J. Pharmacol. 2015. [Epub ahead of print]. doi:10.1111/1440-1681.12452
    • (2015) Br. J. Pharmacol.
    • Jenkin, K.A.1    O'Keefe, L.2    Simcocks, A.C.3
  • 25
    • 0035133295 scopus 로고    scopus 로고
    • Sodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: Hormonal control
    • Féraille E, Doucet A. Sodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: Hormonal control. Physiol. Rev. 2001; 81: 345-418.
    • (2001) Physiol. Rev. , vol.81 , pp. 345-418
    • Féraille, E.1    Doucet, A.2
  • 26
    • 10944229752 scopus 로고    scopus 로고
    • ERK1/2 controls Na, K-ATPase activity and transepithelial sodium transport in the principal cell of the cortical collecting duct of the mouse kidney
    • Michlig S, Mercier A, Doucet A et al. ERK1/2 controls Na, K-ATPase activity and transepithelial sodium transport in the principal cell of the cortical collecting duct of the mouse kidney. J. Biol. Chem. 2004; 279: 51002-12.
    • (2004) J. Biol. Chem. , vol.279 , pp. 51002-51012
    • Michlig, S.1    Mercier, A.2    Doucet, A.3
  • 27
    • 79952700753 scopus 로고    scopus 로고
    • Resveratrol ameliorates early diabetic nephropathy associated with suppression of augmented TGF-β/smad and ERK1/2 signaling in streptozotocin-induced diabetic rats
    • Chen KH, Hung CC, Hsu HH, Jing YH, Yang CW, Chen JK. Resveratrol ameliorates early diabetic nephropathy associated with suppression of augmented TGF-β/smad and ERK1/2 signaling in streptozotocin-induced diabetic rats. Chem. Biol. Interact. 2011; 190: 45-53.
    • (2011) Chem. Biol. Interact. , vol.190 , pp. 45-53
    • Chen, K.H.1    Hung, C.C.2    Hsu, H.H.3    Jing, Y.H.4    Yang, C.W.5    Chen, J.K.6
  • 28
    • 70349576333 scopus 로고    scopus 로고
    • Increased renal Akt/mTOR and MAPK signaling in type I diabetes in the absence of IGF type 1 receptor activation
    • Landau D, Eshet R, Troib A et al. Increased renal Akt/mTOR and MAPK signaling in type I diabetes in the absence of IGF type 1 receptor activation. Endocrine 2009; 36: 126-34.
    • (2009) Endocrine , vol.36 , pp. 126-134
    • Landau, D.1    Eshet, R.2    Troib, A.3
  • 29
    • 83755225879 scopus 로고    scopus 로고
    • Diet-induced obesity up-regulates the abundance of GPR43 and GPR120 in a tissue specific manner
    • Cornall LM, Mathai ML, Hryciw DH, McAinch AJ. Diet-induced obesity up-regulates the abundance of GPR43 and GPR120 in a tissue specific manner. Cell. Physiol. Biochem. 2011; 28: 949-58.
    • (2011) Cell. Physiol. Biochem. , vol.28 , pp. 949-958
    • Cornall, L.M.1    Mathai, M.L.2    Hryciw, D.H.3    McAinch, A.J.4
  • 30
    • 84858439862 scopus 로고    scopus 로고
    • Insights into the regulation of protein abundance from proteomic and transcriptomic analyses
    • Vogel C, Marcotte EM. Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. Nat. Rev. Genet. 2012; 13: 227-32.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 227-232
    • Vogel, C.1    Marcotte, E.M.2
  • 31
    • 20344401675 scopus 로고    scopus 로고
    • Albumin up-regulates the type II transforming growth factor-beta receptor in cultured proximal tubular cells
    • Wolf G, Schroeder R, Ziyadeh FN, Stahl RA. Albumin up-regulates the type II transforming growth factor-beta receptor in cultured proximal tubular cells. Kidney Int. 2004; 66: 1849-58.
    • (2004) Kidney Int. , vol.66 , pp. 1849-1858
    • Wolf, G.1    Schroeder, R.2    Ziyadeh, F.N.3    Stahl, R.A.4
  • 32
    • 0037407267 scopus 로고    scopus 로고
    • Protein uptake disturbs collagen homeostasis in proximal tubule-derived cells
    • Wohlfarth V, Drumm K, Mildenberger S, Freudinger R, Gekle M. Protein uptake disturbs collagen homeostasis in proximal tubule-derived cells. Kidney Int. 2003; 84: S103-9.
    • (2003) Kidney Int. , vol.84 , pp. S103-S109
    • Wohlfarth, V.1    Drumm, K.2    Mildenberger, S.3    Freudinger, R.4    Gekle, M.5
  • 33
    • 0033231441 scopus 로고    scopus 로고
    • Inhibition of Na+-H+ exchange impairs receptor-mediated albumin endocytosis in renal proximal tubule-derived epithelial cells from opossum
    • Gekle M, Drumm K, Mildenberger S, Freudinger R, Gassner B, Silbernagl S. Inhibition of Na+-H+ exchange impairs receptor-mediated albumin endocytosis in renal proximal tubule-derived epithelial cells from opossum. J. Physiol. 1999; 520: 709-21.
    • (1999) J. Physiol. , vol.520 , pp. 709-721
    • Gekle, M.1    Drumm, K.2    Mildenberger, S.3    Freudinger, R.4    Gassner, B.5    Silbernagl, S.6
  • 34
    • 0031890211 scopus 로고    scopus 로고
    • + exchanger 3 accumulates and is functional in recycling endosomes
    • + exchanger 3 accumulates and is functional in recycling endosomes. J. Biol. Chem. 1998; 273: 2035-43.
    • (1998) J. Biol. Chem. , vol.273 , pp. 2035-2043
    • D'Souza, S.1    Garcia-Cabado, A.2    Yu, F.3
  • 35
    • 84859756834 scopus 로고    scopus 로고
    • The epithelial sodium/proton exchanger, NHE3, is necessary for renal and intestinal calcium (re)absorption
    • Pan W, Borovac J, Spicer Z et al. The epithelial sodium/proton exchanger, NHE3, is necessary for renal and intestinal calcium (re)absorption. Am. J. Physiol. Renal. Physiol. 2012; 302: F943-56.
    • (2012) Am. J. Physiol. Renal. Physiol. , vol.302 , pp. F943-F956
    • Pan, W.1    Borovac, J.2    Spicer, Z.3
  • 36
    • 0037340168 scopus 로고    scopus 로고
    • The kidney, hypertension, and obesity
    • Hall JE. The kidney, hypertension, and obesity. Hypertension 2003; 41: 625-33.
    • (2003) Hypertension , vol.41 , pp. 625-633
    • Hall, J.E.1
  • 37
    • 84897502191 scopus 로고    scopus 로고
    • + exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans
    • + exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans. Sci. Transl. Med. 2014; 6: 227ra36.
    • (2014) Sci. Transl. Med. , vol.6 , pp. 227-236
    • Spencer, A.G.1    Labonte, E.D.2    Rosenbaum, D.P.3
  • 39
    • 84867966112 scopus 로고    scopus 로고
    • Does inflammation determine whether obesity is metabolically healthy or unhealthy? The aging perspective
    • Alam I, Ng TP, Larbi A. Does inflammation determine whether obesity is metabolically healthy or unhealthy? The aging perspective Mediators Inflamm. 2012; 2012: 456456.
    • (2012) Mediators Inflamm. , vol.2012 , pp. 456456
    • Alam, I.1    Ng, T.P.2    Larbi, A.3
  • 40
    • 12544256432 scopus 로고    scopus 로고
    • Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation
    • Shiue H, Musch MW, Wang Y, Chang EB, Turner JR. Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation. J. Biol. Chem. 2005; 280: 1688-95.
    • (2005) J. Biol. Chem. , vol.280 , pp. 1688-1695
    • Shiue, H.1    Musch, M.W.2    Wang, Y.3    Chang, E.B.4    Turner, J.R.5
  • 41
    • 84867469210 scopus 로고    scopus 로고
    • Sgk-1 is a positive regulator of constitutive albumin uptake in renal proximal tubule cells
    • Hryciw DH, Kruger WA, Briffa JF et al. Sgk-1 is a positive regulator of constitutive albumin uptake in renal proximal tubule cells. Cell. Physiol. Biochem. 2012; 30: 1215-26.
    • (2012) Cell. Physiol. Biochem. , vol.30 , pp. 1215-1226
    • Hryciw, D.H.1    Kruger, W.A.2    Briffa, J.F.3
  • 43
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • Maffei M, Halaas J, Ravussin E et al. Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1995; 11: 1155-61.
    • (1995) Nat. Med. , vol.11 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3
  • 44
    • 0031954362 scopus 로고    scopus 로고
    • Hyperleptinemia in patients with end-stage renal disease undergoing continuous ambulatory peritoneal dialysis
    • Dagogo-Jack S, Ovalle F, Landt M, Gearing B, Coyne DW. Hyperleptinemia in patients with end-stage renal disease undergoing continuous ambulatory peritoneal dialysis. Perit. Dial. Int. 1998; 18: 34-40.
    • (1998) Perit. Dial. Int. , vol.18 , pp. 34-40
    • Dagogo-Jack, S.1    Ovalle, F.2    Landt, M.3    Gearing, B.4    Coyne, D.W.5
  • 47
    • 84882807441 scopus 로고    scopus 로고
    • Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury
    • Jang HS, Han SJ, Kim JI, Lee S, Lipschutz JH, Park KM. Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury. Biochim. Biophys. Acta 2013; 1832: 1998-2008.
    • (2013) Biochim. Biophys. Acta , vol.1832 , pp. 1998-2008
    • Jang, H.S.1    Han, S.J.2    Kim, J.I.3    Lee, S.4    Lipschutz, J.H.5    Park, K.M.6
  • 49
    • 33749445410 scopus 로고    scopus 로고
    • The role of obesity and its bioclinical correlates in the progression of chronic kidney disease
    • Chalmers L, Kaskel FJ, Bamgbola O. The role of obesity and its bioclinical correlates in the progression of chronic kidney disease. Adv. Chronic Kidney Dis. 2009; 13: 352-64.
    • (2009) Adv. Chronic Kidney Dis. , vol.13 , pp. 352-364
    • Chalmers, L.1    Kaskel, F.J.2    Bamgbola, O.3
  • 51
    • 0030851867 scopus 로고    scopus 로고
    • Overexpression of GLUT2 gene in renal proximal tubules of diabetic Zucker rats
    • Kamran M, Peterson RG, Dominguez JH. Overexpression of GLUT2 gene in renal proximal tubules of diabetic Zucker rats. J. Am. Soc. Nephrol. 1997; 8: 943-8.
    • (1997) J. Am. Soc. Nephrol. , vol.8 , pp. 943-948
    • Kamran, M.1    Peterson, R.G.2    Dominguez, J.H.3
  • 52
    • 0031776099 scopus 로고    scopus 로고
    • Effect of the aldose reductase inhibitor tolrestat on nerve conduction velocity, Na/K ATPase activity, and polyols in red blood cells, sciatic nerve, kidney cortex, and kidney medulla of diabetic rats
    • Raccah D, Coste T, Cameron NE, Dufayet D, Vague P, Hohman TC. Effect of the aldose reductase inhibitor tolrestat on nerve conduction velocity, Na/K ATPase activity, and polyols in red blood cells, sciatic nerve, kidney cortex, and kidney medulla of diabetic rats. J. Diabetes Complications 1998; 12: 154-62.
    • (1998) J. Diabetes Complications , vol.12 , pp. 154-162
    • Raccah, D.1    Coste, T.2    Cameron, N.E.3    Dufayet, D.4    Vague, P.5    Hohman, T.C.6
  • 53
    • 84862795525 scopus 로고    scopus 로고
    • Ouabain and insulin induce sodium pump endocytosis in renal epithelium
    • Gupta S, Yan Y, Malhotra D et al. Ouabain and insulin induce sodium pump endocytosis in renal epithelium. Hypertension 2012; 59: 665-72.
    • (2012) Hypertension , vol.59 , pp. 665-672
    • Gupta, S.1    Yan, Y.2    Malhotra, D.3
  • 54
    • 84861165074 scopus 로고    scopus 로고
    • Effects of insulin on Na and K transporters in the rat CCD
    • Frindt G, Palmer LG. Effects of insulin on Na and K transporters in the rat CCD. Am. J. Physiol. Renal. Physiol. 2012; 302: F1227-33.
    • (2012) Am. J. Physiol. Renal. Physiol. , vol.302 , pp. F1227-F1233
    • Frindt, G.1    Palmer, L.G.2
  • 55
    • 35649015179 scopus 로고    scopus 로고
    • The orphan receptor GPR55 is a novel cannabinoid receptor
    • Ryberg E, Larsson N, Sjögren S et al. The orphan receptor GPR55 is a novel cannabinoid receptor. Br. J. Pharmacol. 2007; 152: 1092-101.
    • (2007) Br. J. Pharmacol. , vol.152 , pp. 1092-1101
    • Ryberg, E.1    Larsson, N.2    Sjögren, S.3
  • 56
    • 84922631037 scopus 로고    scopus 로고
    • Elevated cannabinoid receptor 1 and G protein-coupled receptor 55 expression in proximal tubule cells and whole kidney exposed to diabetic conditions
    • Jenkin KA, McAinch AJ, Zhang Y, Kelly DJ, Hryciw DH. Elevated cannabinoid receptor 1 and G protein-coupled receptor 55 expression in proximal tubule cells and whole kidney exposed to diabetic conditions. Clin. Exp. Pharmacol. Physiol. 2015; 42: 256-62.
    • (2015) Clin. Exp. Pharmacol. Physiol. , vol.42 , pp. 256-262
    • Jenkin, K.A.1    McAinch, A.J.2    Zhang, Y.3    Kelly, D.J.4    Hryciw, D.H.5


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