Acute leptin exposure reduces megalin expression and upregulates TGFβ1 in cultured renal proximal tubule cells

Molecular and Cellular Endocrinology

Volumn 401, Issue , 2015, Pages 25-34

  Briffa, Jessica F ^a,b   Grinfeld, Esther ^a   Mathai, Michael L ^a   Poronnik, Phillip ^c   McAinch, Andrew J ^a   Hryciw, Deanne H ^a,b  

^a VICTORIA UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

AMPK; Leptin; Megalin; Proximal tubule; TGF 1

Indexed keywords

ADENYLATE KINASE; AMP KINASE ALPHA; LEPTIN; MEGALIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; KIDNEY TUBULE CELL; MALE; MOLECULAR INTERACTION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CYTOLOGY; KIDNEY PROXIMAL TUBULE; METABOLISM; OPOSSUM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELLS, CULTURED; KIDNEY TUBULES, PROXIMAL; LEPTIN; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2; MALE; OPOSSUMS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84916608391     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2014.11.024     Document Type: Article

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