Increased renal Akt/mTOR and MAPK signaling in type I diabetes in the absence of IGF type 1 receptor activation

Endocrine

Volumn 36, Issue 1, 2009, Pages 126-134

  Landau, Daniel ^a   Eshet, Renanah ^a   Troib, Ariel ^a   Gurman, Yotam ^a   Chen, Yu ^a,b   Rabkin, Ralph ^b   Segev, Yael ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Diabetic nephropathy; Growth hormone receptor; JAK2; Phosphorylation; STAT5

Indexed keywords

GROWTH HORMONE; JAK2 PROTEIN, MOUSE; JANUS KINASE 2; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PROTEIN KINASE; PROTEIN KINASE B; SOCS2 PROTEIN, MOUSE; SOMATOMEDIN C RECEPTOR; STAT3 PROTEIN; STAT3 PROTEIN, MOUSE; STAT5 PROTEIN; STAT5A PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; DIABETIC NEPHROPATHY; EXPERIMENTAL DIABETES MELLITUS; GENETICS; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY; MALE; METABOLISM; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; GROWTH HORMONE; JANUS KINASE 2; KIDNEY; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; RNA, MESSENGER; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 70349576333     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-009-9190-2     Document Type: Article

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