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Volumn 354, Issue 3, 2015, Pages 302-309

High-mobility group box 1 mediates epithelial-to-mesenchymal transition in pulmonary fibrosis involving transforming growth factor-β1/Smad2/3 signaling

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; HIGH MOBILITY GROUP B1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN; VIMENTIN; ACTIN; CADHERIN; HMGB1 PROTEIN, HUMAN; HYDROXYPROLINE; RECOMBINANT PROTEIN;

EID: 84941554281     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.222372     Document Type: Article
Times cited : (62)

References (39)
  • 1
    • 84875260698 scopus 로고    scopus 로고
    • Roles of p38 MAPK and JNK in TGFb1- induced human alveolar epithelial to mesenchymal transition
    • Chen HH, Zhou XL, Shi YL, and Yang J (2013) Roles of p38 MAPK and JNK in TGFb1- induced human alveolar epithelial to mesenchymal transition. Arch Med Res 44:93-98.
    • (2013) Arch Med Res , vol.44 , pp. 93-98
    • Chen, H.H.1    Zhou, X.L.2    Shi, Y.L.3    Yang, J.4
  • 2
    • 84896051627 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition involved in pulmonary fibrosis induced by multi-walled carbon nanotubes via TGF-beta/Smad signaling pathway
    • Chen T, Nie H, Gao X, Yang J, Pu J, Chen Z, Cui X, Wang Y, Wang H, and Jia G (2014) Epithelial-mesenchymal transition involved in pulmonary fibrosis induced by multi-walled carbon nanotubes via TGF-beta/Smad signaling pathway. Toxicol Lett 226:150-162.
    • (2014) Toxicol Lett , vol.226 , pp. 150-162
    • Chen, T.1    Nie, H.2    Gao, X.3    Yang, J.4    Pu, J.5    Chen, Z.6    Cui, X.7    Wang, Y.8    Wang, H.9    Jia, G.10
  • 3
    • 84055201032 scopus 로고    scopus 로고
    • Gradual increase of high mobility group protein b1 in the lungs after the onset of acute exacerbation of idiopathic pulmonary fibrosis
    • Ebina M, Taniguchi H, Miyasho T, Yamada S, Shibata N, Ohta H, Hisata S, Ohkouchi S, Tamada T, and Nishimura H, et al. (2011) Gradual increase of high mobility group protein b1 in the lungs after the onset of acute exacerbation of idiopathic pulmonary fibrosis. Pulm Med 2011:916486.
    • (2011) Pulm Med , vol.2011 , pp. 916486
    • Ebina, M.1    Taniguchi, H.2    Miyasho, T.3    Yamada, S.4    Shibata, N.5    Ohta, H.6    Hisata, S.7    Ohkouchi, S.8    Tamada, T.9    Nishimura, H.10
  • 6
    • 67650979221 scopus 로고    scopus 로고
    • Antagonist of the type-1 ANG II receptor prevents against LPS-induced septic shock in rats
    • Hagiwara S, Iwasaka H, Hidaka S, Hasegawa A, Koga H, and Noguchi T (2009) Antagonist of the type-1 ANG II receptor prevents against LPS-induced septic shock in rats. Intensive Care Med 35:1471-1478.
    • (2009) Intensive Care Med , vol.35 , pp. 1471-1478
    • Hagiwara, S.1    Iwasaka, H.2    Hidaka, S.3    Hasegawa, A.4    Koga, H.5    Noguchi, T.6
  • 8
    • 33646464082 scopus 로고    scopus 로고
    • Angelica sinensis down-regulates hydroxyproline and Tgfb1 and provides protection in mice with radiation-induced pulmonary fibrosis
    • Han G, Zhou YF, Zhang MS, Cao Z, Xie CH, Zhou FX, Peng M, and Zhang WJ (2006) Angelica sinensis down-regulates hydroxyproline and Tgfb1 and provides protection in mice with radiation-induced pulmonary fibrosis. Radiat Res 165:546-552.
    • (2006) Radiat Res , vol.165 , pp. 546-552
    • Han, G.1    Zhou, Y.F.2    Zhang, M.S.3    Cao, Z.4    Xie, C.H.5    Zhou, F.X.6    Peng, M.7    Zhang, W.J.8
  • 10
    • 84877722045 scopus 로고    scopus 로고
    • Exogenous high-mobility group box 1 protein prevents postinfarction adverse myocardial remodeling through TGFb/Smad signaling pathway
    • He Y, Zhou X, Zheng X, and Jiang X (2013) Exogenous high-mobility group box 1 protein prevents postinfarction adverse myocardial remodeling through TGFb/Smad signaling pathway. J Cell Biochem 114:1634-1641.
    • (2013) J Cell Biochem , vol.114 , pp. 1634-1641
    • He, Y.1    Zhou, X.2    Zheng, X.3    Jiang, X.4
  • 12
    • 84880625696 scopus 로고    scopus 로고
    • Diallylsulfide attenuates excessive collagen production and apoptosis in a rat model of bleomycin induced pulmonary fibrosis through the involvement of protease activated receptor-2
    • Kalayarasan S, Sriram N, Soumyakrishnan S, and Sudhandiran G (2013) Diallylsulfide attenuates excessive collagen production and apoptosis in a rat model of bleomycin induced pulmonary fibrosis through the involvement of protease activated receptor-2. Toxicol Appl Pharmacol 271:184-195.
    • (2013) Toxicol Appl Pharmacol , vol.271 , pp. 184-195
    • Kalayarasan, S.1    Sriram, N.2    Soumyakrishnan, S.3    Sudhandiran, G.4
  • 13
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R and Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119:1420-1428.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 14
    • 84904092153 scopus 로고    scopus 로고
    • Involvement of the nuclear high mobility group B1 peptides released from injured hepatocytes in murine hepatic fibrogenesis
    • Kao YH, Lin YC, Tsai MS, Sun CK, Yuan SS, Chang CY, Jawan B, and Lee PH (2014) Involvement of the nuclear high mobility group B1 peptides released from injured hepatocytes in murine hepatic fibrogenesis. Biochim Biophys Acta 1842: 1720-1732.
    • (2014) Biochim Biophys Acta , vol.1842 , pp. 1720-1732
    • Kao, Y.H.1    Lin, Y.C.2    Tsai, M.S.3    Sun, C.K.4    Yuan, S.S.5    Chang, C.Y.6    Jawan, B.7    Lee, P.H.8
  • 15
    • 0035181092 scopus 로고    scopus 로고
    • Regulation of the effects of TGF-beta 1 by activation of latent TGF-beta 1 and differential expression of TGF-beta receptors (T beta R-I and T beta R-II) in idiopathic pulmonary fibrosis
    • Khalil N, Parekh TV, O'Connor R, Antman N, Kepron W, Yehaulaeshet T, Xu YD, and Gold LI (2001) Regulation of the effects of TGF-beta 1 by activation of latent TGF-beta 1 and differential expression of TGF-beta receptors (T beta R-I and T beta R-II) in idiopathic pulmonary fibrosis. Thorax 56:907-915.
    • (2001) Thorax , vol.56 , pp. 907-915
    • Khalil, N.1    Parekh, T.V.2    O'Connor, R.3    Antman, N.4    Kepron, W.5    Yehaulaeshet, T.6    Xu, Y.D.7    Gold, L.I.8
  • 17
    • 82755161052 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis
    • King TE Jr, Pardo A, and Selman M (2011) Idiopathic pulmonary fibrosis. Lancet 378:1949-1961.
    • (2011) Lancet , vol.378 , pp. 1949-1961
    • King, T.E.1    Pardo, A.2    Selman, M.3
  • 18
    • 84873436135 scopus 로고    scopus 로고
    • Inhibitory effects of epi-sesamin on HMGB1-induced vascular barrier disruptive responses in vitro and in vivo
    • Lee W, Ku SK, Kim JA, Lee T, and Bae JS (2013) Inhibitory effects of epi-sesamin on HMGB1-induced vascular barrier disruptive responses in vitro and in vivo. Toxicol Appl Pharmacol 267:201-208.
    • (2013) Toxicol Appl Pharmacol , vol.267 , pp. 201-208
    • Lee, W.1    Ku, S.K.2    Kim, J.A.3    Lee, T.4    Bae, J.S.5
  • 19
    • 84916601500 scopus 로고    scopus 로고
    • Total extract of Yupingfeng attenuates bleomycin-induced pulmonary fibrosis in rats
    • Li L, Li D, Xu L, Zhao P, Deng Z, Mo X, Li P, Qi L, Li J, and Gao J (2015) Total extract of Yupingfeng attenuates bleomycin-induced pulmonary fibrosis in rats. Phytomedicine 22:111-119.
    • (2015) Phytomedicine , vol.22 , pp. 111-119
    • Li, L.1    Li, D.2    Xu, L.3    Zhao, P.4    Deng, Z.5    Mo, X.6    Li, P.7    Qi, L.8    Li, J.9    Gao, J.10
  • 20
    • 84911379523 scopus 로고    scopus 로고
    • Emerging role of HMGB1 in fibrotic diseases
    • Li LC, Gao J, and Li J (2014a) Emerging role of HMGB1 in fibrotic diseases. J Cell Mol Med 18:2331-2339.
    • (2014) J Cell Mol Med , vol.18 , pp. 2331-2339
    • Li, L.C.1    Gao, J.2    Li, J.3
  • 21
    • 84908120931 scopus 로고    scopus 로고
    • Functions of galectin-3 and its role in fibrotic diseases
    • Li LC, Li J, and Gao J (2014b) Functions of galectin-3 and its role in fibrotic diseases. J Pharmacol Exp Ther 351:336-343.
    • (2014) J Pharmacol Exp Ther , vol.351 , pp. 336-343
    • Li, L.C.1    Li, J.2    Gao, J.3
  • 22
    • 84907609978 scopus 로고    scopus 로고
    • SET-mediated NDRG1 inhibition is involved in acquisition of epithelial-tomesenchymal transition phenotype and cisplatin resistance in human lung cancer cell
    • Liu H, Gu Y, Yin J, Zheng G, Wang C, Zhang Z, Deng M, Liu J, Jia X, and He Z (2014) SET-mediated NDRG1 inhibition is involved in acquisition of epithelial-tomesenchymal transition phenotype and cisplatin resistance in human lung cancer cell. Cell Signal 26:2710-2720.
    • (2014) Cell Signal , vol.26 , pp. 2710-2720
    • Liu, H.1    Gu, Y.2    Yin, J.3    Zheng, G.4    Wang, C.5    Zhang, Z.6    Deng, M.7    Liu, J.8    Jia, X.9    He, Z.10
  • 23
    • 84879117465 scopus 로고    scopus 로고
    • Pathogenesis, current treatments and future directions for idiopathic pulmonary fibrosis
    • Loomis-King H, Flaherty KR, and Moore BB (2013) Pathogenesis, current treatments and future directions for idiopathic pulmonary fibrosis. Curr Opin Pharmacol 13: 377-385.
    • (2013) Curr Opin Pharmacol , vol.13 , pp. 377-385
    • Loomis-King, H.1    Flaherty, K.R.2    Moore, B.B.3
  • 24
    • 78449263799 scopus 로고    scopus 로고
    • Highmobility group box protein 1: A novel mediator of inflammatory-induced renal epithelial-mesenchymal transition
    • Lynch J, Nolan S, Slattery C, Feighery R, Ryan MP, and McMorrow T (2010) Highmobility group box protein 1: A novel mediator of inflammatory-induced renal epithelial-mesenchymal transition. Am J Nephrol 32:590-602.
    • (2010) Am J Nephrol , vol.32 , pp. 590-602
    • Lynch, J.1    Nolan, S.2    Slattery, C.3    Feighery, R.4    Ryan, M.P.5    McMorrow, T.6
  • 25
    • 84876401638 scopus 로고    scopus 로고
    • Silibinin synergizes with histone deacetylase and DNA methyltransferase inhibitors in upregulating E-cadherin expression together with inhibition of migration and invasion of human non-small cell lung cancer cells
    • Mateen S, Raina K, Agarwal C, Chan D, and Agarwal R (2013) Silibinin synergizes with histone deacetylase and DNA methyltransferase inhibitors in upregulating E-cadherin expression together with inhibition of migration and invasion of human non-small cell lung cancer cells. J Pharmacol Exp Ther 345: 206-214.
    • (2013) J Pharmacol Exp Ther , vol.345 , pp. 206-214
    • Mateen, S.1    Raina, K.2    Agarwal, C.3    Chan, D.4    Agarwal, R.5
  • 27
    • 80053151867 scopus 로고    scopus 로고
    • Glycyrrhizin prevents liver injury by inhibition of high-mobility group box 1 production by Kupffer cells after ischemia-reperfusion in rats
    • Ogiku M, Kono H, Hara M, Tsuchiya M, and Fujii H (2011) Glycyrrhizin prevents liver injury by inhibition of high-mobility group box 1 production by Kupffer cells after ischemia-reperfusion in rats. J Pharmacol Exp Ther 339: 93-98.
    • (2011) J Pharmacol Exp Ther , vol.339 , pp. 93-98
    • Ogiku, M.1    Kono, H.2    Hara, M.3    Tsuchiya, M.4    Fujii, H.5
  • 29
    • 79952717349 scopus 로고    scopus 로고
    • An official ATS/ERS/JRS/ALAT statement: Idiopathic pulmonary fibrosis: Evidence-based guidelines for diagnosis and management
    • ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis
    • Raghu G, Collard HR, Egan JJ, Martinez FJ, Behr J, Brown KK, Colby TV, Cordier JF, Flaherty KR, and Lasky JA, et al.; ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis (2011) An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 183:788-824.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 788-824
    • Raghu, G.1    Collard, H.R.2    Egan, J.J.3    Martinez, F.J.4    Behr, J.5    Brown, K.K.6    Colby, T.V.7    Cordier, J.F.8    Flaherty, K.R.9    Lasky, J.A.10
  • 31
    • 0041827226 scopus 로고    scopus 로고
    • The epithelial/fibroblastic pathway in the pathogenesis of idiopathic pulmonary fibrosis
    • Selman M and Pardo A (2003) The epithelial/fibroblastic pathway in the pathogenesis of idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol 29 (3 Suppl): S93-S97.
    • (2003) Am J Respir Cell Mol Biol , vol.29 , Issue.3 , pp. S93-S97
    • Selman, M.1    Pardo, A.2
  • 32
    • 79954989615 scopus 로고    scopus 로고
    • Regulation of transforming growth factor-b1-dependent integrin b6 expression by p38 mitogenactivated protein kinase in bile duct epithelial cells
    • Sullivan BP, Kassel KM, Manley S, Baker AK, and Luyendyk JP (2011) Regulation of transforming growth factor-b1-dependent integrin b6 expression by p38 mitogenactivated protein kinase in bile duct epithelial cells. J Pharmacol Exp Ther 337: 471-478.
    • (2011) J Pharmacol Exp Ther , vol.337 , pp. 471-478
    • Sullivan, B.P.1    Kassel, K.M.2    Manley, S.3    Baker, A.K.4    Luyendyk, J.P.5
  • 33
    • 33947411686 scopus 로고    scopus 로고
    • Effects of the protein kinase inhibitor, imatinib mesylate, on epithelial/mesenchymal phenotypes: Implications for treatment of fibrotic diseases
    • Vittal R, Zhang H, Han MK, Moore BB, Horowitz JC, and Thannickal VJ (2007) Effects of the protein kinase inhibitor, imatinib mesylate, on epithelial/mesenchymal phenotypes: implications for treatment of fibrotic diseases. J Pharmacol Exp Ther 321:35-44.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 35-44
    • Vittal, R.1    Zhang, H.2    Han, M.K.3    Moore, B.B.4    Horowitz, J.C.5    Thannickal, V.J.6
  • 35
    • 17844384822 scopus 로고    scopus 로고
    • Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis
    • Willis BC, Liebler JM, Luby-Phelps K, Nicholson AG, Crandall ED, du Bois RM, and Borok Z (2005) Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol 166:1321-1332.
    • (2005) Am J Pathol , vol.166 , pp. 1321-1332
    • Willis, B.C.1    Liebler, J.M.2    Luby-Phelps, K.3    Nicholson, A.G.4    Crandall, E.D.5    Du Bois, R.M.6    Borok, Z.7
  • 36
    • 84911455604 scopus 로고    scopus 로고
    • Total polysaccharide of Yupingfeng protects against bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor-b1-mediated type I collagen abnormal deposition in rats
    • Xu L, Li LC, Zhao P, Qi LW, Li P, Gao J, and Fei GH (2014a) Total polysaccharide of Yupingfeng protects against bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor-b1-mediated type I collagen abnormal deposition in rats. J Pharm Pharmacol 66:1786-1795.
    • (2014) J Pharm Pharmacol , vol.66 , pp. 1786-1795
    • Xu, L.1    Li, L.C.2    Zhao, P.3    Qi, L.W.4    Li, P.5    Gao, J.6    Fei, G.H.7
  • 37
    • 84905013592 scopus 로고    scopus 로고
    • Astragaloside IV ameliorates renal fibrosis via the inhibition of mitogenactivated protein kinases and antiapoptosis in vivo and in vitro
    • Xu W, Shao X, Tian L, Gu L, Zhang M, Wang Q, Wu B, Wang L, Yao J, Xu X, et al. (2014b) Astragaloside IV ameliorates renal fibrosis via the inhibition of mitogenactivated protein kinases and antiapoptosis in vivo and in vitro. J Pharmacol Exp Ther 350:552-562.
    • (2014) J Pharmacol Exp Ther , vol.350 , pp. 552-562
    • Xu, W.1    Shao, X.2    Tian, L.3    Gu, L.4    Zhang, M.5    Wang, Q.6    Wu, B.7    Wang, L.8    Yao, J.9    Xu, X.10
  • 38
    • 33645216539 scopus 로고    scopus 로고
    • Losartan attenuates bleomycin-induced pulmonary fibrosis in rats
    • Yao HW, Zhu JP, Zhao MH, and Lu Y (2006) Losartan attenuates bleomycin-induced pulmonary fibrosis in rats. Respiration 73:236-242.
    • (2006) Respiration , vol.73 , pp. 236-242
    • Yao, H.W.1    Zhu, J.P.2    Zhao, M.H.3    Lu, Y.4
  • 39
    • 84921299153 scopus 로고    scopus 로고
    • Protocatechuic aldehyde ameliorates experimental pulmonary fibrosis by modulating HMGB1/RAGE pathway
    • Zhang L, Ji Y, Kang Z, Lv C, and Jiang W (2015) Protocatechuic aldehyde ameliorates experimental pulmonary fibrosis by modulating HMGB1/RAGE pathway. Toxicol Appl Pharmacol 283:50-56.
    • (2015) Toxicol Appl Pharmacol , vol.283 , pp. 50-56
    • Zhang, L.1    Ji, Y.2    Kang, Z.3    Lv, C.4    Jiang, W.5


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