Astragaloside IV ameliorates renal fibrosis via the inhibition of mitogen-activated protein kinases and antiapoptosis in vivo and in vitro

Journal of Pharmacology and Experimental Therapeutics

Volumn 350, Issue 3, 2014, Pages 552-562

  Xu, Weijia ^a   Shao, Xinghua ^a   Tian, Lei ^a   Gu, Leyi ^a   Zhang, Minfang ^a   Wang, Qin ^a   Wu, Bei ^a   Wang, Ling ^a   Yao, Jufang ^b   Xu, Xiaoping ^b   Mou, Shan ^a   Ni, Zhaohui ^a  

^a School of Medicine   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ASTRAGALOSIDE IV; CASPASE 3; COLLAGEN TYPE 4; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY FIBROSIS; KIDNEY MASS; KIDNEY TUBULE CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL PROTECTION; URETER OBSTRUCTION;

ANIMALS; APOPTOSIS; FIBROSIS; HUMANS; KIDNEY DISEASES; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; SAPONINS; TRITERPENES;

EID: 84905013592     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.214205     Document Type: Article

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