Paradoxical function for the receptor for advanced glycation end products in mouse models of pulmonary fibrosis

International Journal of Clinical and Experimental Pathology

Volumn 4, Issue 3, 2011, Pages 241-254

  Englert, Judson M ^a   Kliment, Corrine R ^a   Ramsgaard, Lasse ^a   Milutinovic, Pavle S ^a   Crum, Lauren ^a   Tobolewski, Jacob M ^a   Oury, Tim D ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Asbestos; Bleomycin; RAGE knockout; Soluble RAGE

Indexed keywords

ADVANCED GLYCOSYLATION END PRODUCT RECEPTOR; ADVANCED GLYCOSYLATION END-PRODUCT RECEPTOR; BLEOMYCIN; IMMUNOGLOBULIN RECEPTOR;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; GENETICS; LUNG FIBROSIS; MALE; METABOLISM; MOUSE; MOUSE MUTANT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; BLEOMYCIN; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PULMONARY FIBROSIS; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION;

EID: 79956371191     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Schmidt AM, Vianna M, Gerlach M, Brett J, Ryan J, Kao J, Esposito C, Hegarty H, Hurley W, Clauss M and et al. Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface. J Biol Chem 1992; 267: 14987-14997.
2. Englert JM, Hanford LE, Kaminski N, Tobolewski JM, Tan RJ, Fattman CL, Ramsgaard L, Richards TJ, Loutaev I, Nawroth PP, Kasper M, Bierhaus A and Oury TD. A role for the receptor for advanced glycation end products in idiopathic pulmonary fibrosis. Am J Pathol 2008; 172: 583-591.
3. Hanford LE, Fattman CL, Shaefer LM, Enghild JJ, Valnickova Z and Oury TD. Regulation of receptor for advanced glycation end products during bleomycin-induced lung injury. Am J Respir Cell Mol Biol 2003; 29: S77-81.
4. Queisser MA, Kouri FM, Konigshoff M, Wygrecka M, Schubert U, Eickelberg O and Preissner KT. Loss of RAGE in Pulmonary Fibrosis: Molecular Relations to Functional Changes in Pulmonary Cell Types. Am J Respir Cell Mol Biol 2008;
5. Brett J, Schmidt AM, Yan SD, Zou YS, Weidman E, Pinsky D, Nowygrod R, Neeper M, Przysiecki C, Shaw A and et al. Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues. Am J Pathol 1993; 143: 1699-1712.
6. Ramsgaard L, Englert JM, Tobolewski J, Tomai L, Fattman CL, Leme AS, Kaynar AM, Shapiro SD, Enghild JJ and Oury TD. The role of the receptor for advanced glycation end-products in a murine model of silicosis. PLoS One 2010; 5: e9604.
7. He M, Kubo H, Ishizawa K, Hegab AE, Yamamoto Y, Yamamoto H and Yamaya M. The role of the receptor for advanced glycation endproducts in lung fibrosis. Am J Physiol Lung Cell Mol Physiol 2007; 293: L1427-1436.
8. Bargagli E, Penza F, Bianchi N, Olivieri C, Bennett D, Prasse A and Rottoli P. Controversial role of RAGE in the pathogenesis of idiopathic pulmonary fibrosis. Respir Physiol Neurobiol 2009; 165: 119-120; author reply 121-112.
9. Zhang H, Tasaka S, Shiraishi Y, Fukunaga K, Yamada W, Seki H, Ogawa Y, Miyamoto K, Nakano Y, Hasegawa N, Miyasho T, Maruyama I and Ishizaka A. Role of Soluble Receptor for Advanced Glycation End-Products on Endotoxin-Induced Lung Injury. Am J Respir Crit Care Med 2008;
10. Demling N, Ehrhardt C, Kasper M, Laue M, Knels L and Rieber EP. Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells. Cell Tissue Res 2006; 323: 475-488.
11. Fehrenbach H, Kasper M, Tschernig T, Shearman MS, Schuh D and Muller M. Receptor for advanced glycation endproducts (RAGE) exhibits highly differential cellular and subcellular localisation in rat and human lung. Cell Mol Biol (Noisy-le-grand) 1998; 44: 1147-1157.
12. Shirasawa M, Fujiwara N, Hirabayashi S, Ohno H, Iida J, Makita K and Hata Y. Receptor for advanced glycation end-products is a marker of type I lung alveolar cells. Genes Cells 2004; 9: 165-174.
13. Tan RJ, Fattman CL, Watkins SC and Oury TD. Redistribution of pulmonary EC-SOD after exposure to asbestos. J Appl Physiol 2004; 97: 2006-2013.
14. Englert JM, Ramsgaard L, Valnickova Z, Enghild JJ and Oury TD. Large scale isolation and purification of soluble RAGE from lung tissue. Protein Expr Purif 2008; 61: 99-101.
15. Liu R, Mori S, Wake H, Zhang J, Liu K, Izushi Y, Takahashi HK, Peng B and Nishibori M. Establishment of in vitro binding assay of high mobility group box-1 and S100A12 to receptor for advanced glycation endproducts: heparin's effect on binding. Acta Med Okayama 2009; 63: 203-211.
16. Wendt TM, Tanji N, Guo J, Kislinger TR, Qu W, Lu Y, Bucciarelli LG, Rong LL, Moser B, Markowitz GS, Stein G, Bierhaus A, Liliensiek B, Arnold B, Nawroth PP, Stern DM, D'Agati VD and Schmidt AM. RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy. Am J Pathol 2003; 162: 1123-1137.
17. Park L, Raman KG, Lee KJ, Lu Y, Ferran LJ, Jr., Chow WS, Stern D and Schmidt AM. Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts. Nat Med 1998; 4: 1025-1031.
18. Woessner JF. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Archives of Biochemistry and Biophysics 1961; 93: 440-447.
19. Fattman CL, Chu CT, Kulich SM, Enghild JJ and Oury TD. Altered expression of extracellular superoxide dismutase in mouse lung after bleomycin treatment. Free Radic Biol Med 2001; 31: 1198-1207.
20. Corti M, Brody AR and Harrison JH. Isolation and primary culture of murine alveolar type II cells. Am J Respir Cell Mol Biol 1996; 14: 309-315.
21. Rice WR, Conkright JJ, Na CL, Ikegami M, Shannon JM and Weaver TE. Maintenance of the mouse type II cell phenotype in vitro. Am J Physiol Lung Cell Mol Physiol 2002; 283: L256-264.
22. Kliment CR, Englert JM, Gochuico BR, Yu G, Kaminski N, Rosas I and Oury TD. Oxidative stress alters syndecan-1 distribution in lungs with pulmonary fibrosis. J Biol Chem 2009; 284: 3537-3545.
23. Finkelstein JN, Maniscalco WM and Shapiro DL. Properties of freshly isolated type II alveolar epithelial cells. Biochim Biophys Acta 1983; 762: 398-404.
24. Liang CC, Park AY and Guan JL. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2007; 2: 329-333.
25. Li J and Schmidt AM. Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products. J Biol Chem 1997; 272: 16498-16506.
26. Schmidt AM, Yan SD, Wautier JL and Stern D. Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis. Circ Res 1999; 84: 489-497.
27. Li JH, Wang W, Huang XR, Oldfield M, Schmidt AM, Cooper ME and Lan HY. Advanced glycation end products induce tubular epithelialmyofibroblast transition through the RAGEERK1/ 2 MAP kinase signaling pathway. Am J Pathol 2004; 164: 1389-1397.
28. Bierhaus A, Haslbeck KM, Humpert PM, Liliensiek B, Dehmer T, Morcos M, Sayed AA, Andrassy M, Schiekofer S, Schneider JG, Schulz JB, Heuss D, Neundorfer B, Dierl S, Huber J, Tritschler H, Schmidt AM, Schwaninger M, Haering HU, Schleicher E, Kasper M, Stern DM, Arnold B and Nawroth PP. Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. J Clin Invest 2004; 114: 1741-1751.
29. Lutterloh EC, Opal SM, Pittman DD, Keith JC, Jr., Tan XY, Clancy BM, Palmer H, Milarski K, Sun Y, Palardy JE, Parejo NA and Kessimian N. Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection. Crit Care 2007; 11: R122.
30. Yamamoto Y, Kato I, Doi T, Yonekura H, Ohashi S, Takeuchi M, Watanabe T, Yamagishi S, Sakurai S, Takasawa S, Okamoto H and Yamamoto H. Development and prevention of advanced diabetic nephropathy in RAGEoverexpressing mice. J Clin Invest 2001; 108: 261-268.
31. Wear-Maggitti K, Lee J, Conejero A, Schmidt AM, Grant R and Breitbart A. Use of topical sRAGE in diabetic wounds increases neovascularization and granulation tissue formation. Ann Plast Surg 2004; 52: 519-521; discussion 522.
32. Gongora MC, Lob HE, Landmesser U, Guzik TJ, Martin WD, Ozumi K, Wall SM, Wilson DS, Murthy N, Gravanis M, Fukai T and Harrison DG. Loss of extracellular superoxide dismutase leads to acute lung damage in the presence of ambient air: a potential mechanism underlying adult respiratory distress syndrome. Am J Pathol 2008; 173: 915-926.