Phosphorylation of FE65 Ser610 by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing

Biochemical Journal

Volumn 470, Issue 3, 2015, Pages 303-317

  Chow, Wan Ning Vanessa ^a   Ngo, Jacky Chi Ki ^a   Li, Wen ^a   Chen, Yu Wai ^b   Tam, Ka Ming Vincent ^a   Chan, Ho Yin Edwin ^a   Miller, Christopher C J ^c   Lau, Kwok Fai ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Alzheimer's disease; Amyloid precursor protein (APP); Amyloid peptide; FE65; Protein degradation; Serum and glucocorticoid induced kinase 1 (SGK1)

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; PROTEASOME; PROTEIN FE65; SERINE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; APBB1 PROTEIN, HUMAN; APP PROTEIN, HUMAN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; IMMEDIATE EARLY PROTEIN; NERVE PROTEIN; NUCLEAR PROTEIN; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN; SECRETASE; SERUM-GLUCOCORTICOID REGULATED KINASE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; FEMALE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CHLOROCEBUS AETHIOPS; CHO CELL LINE; COS 1 CELL LINE; CRICETULUS; GENETICS; HEK293 CELL LINE; METABOLISM; PHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN STABILITY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BINDING SITES; CERCOPITHECUS AETHIOPS; CHO CELLS; COS CELLS; CRICETULUS; HEK293 CELLS; HUMANS; IMMEDIATE-EARLY PROTEINS; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STABILITY; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; RECOMBINANT PROTEINS; SERINE;

EID: 84941349116     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20141485     Document Type: Article

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