Anthocyanins inhibit high-glucose-induced cholesterol accumulation and inflammation by activating LXRα pathway in HK-2 cells

Drug Design, Development and Therapy

Volumn 9, Issue , 2015, Pages 5099-5113

  Du, Chunyang ^a,b   Shi, Yonghong ^a,b   Ren, Yunzhuo ^a,b   Wu, Haijiang ^a,b   Yao, Fang ^a,b   Wei, Jinying ^a,b   Wu, Ming ^a,b   Hou, Yanjuan ^a,b   Duan, Huijun ^a,b  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Hebei Key Laboratory of Kidney Disease   (China)

Author keywords

3 O glucoside chloride; Cyanidin chloride; Diabetic nephropathy; Inflammation; Liver X receptor alpha

Indexed keywords

ABC TRANSPORTER A1; ANTHOCYANIN; CHOLESTEROL; CYANIDIN 3 O BETA GLUCOSIDE; CYANIDIN CHLORIDE; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LIVER X RECEPTOR ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RNA 18S; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; ABCA1 PROTEIN, HUMAN; ANTIINFLAMMATORY AGENT; AUTACOID; CYANIDIN; CYANIDIN 3-O-GLUCOSIDE; GLUCOSIDE; LIVER X RECEPTOR; NR1H3 PROTEIN, HUMAN; ORPHAN NUCLEAR RECEPTOR;

18S GENE; ABCA1 GENE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOACCUMULATION; CELL LINE; CELL VIABILITY; CELLULAR DISTRIBUTION; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY TEST; DIABETIC NEPHROPATHY; DRUG INHIBITION; DRUG STRUCTURE; GENE EXPRESSION REGULATION; HK 2 CELL LINE; ICAM1 GENE; INFLAMMATION; INTRACELLULAR SIGNALING; LXRALPHA GENE; MCP1 GENE; METABOLIC REGULATION; PPARALPHA GENE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TGFBETA1 GENE; AGONISTS; DIABETIC NEPHROPATHIES; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; HUMAN; KIDNEY; METABOLISM; NEPHRITIS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTOR;

ANTHOCYANINS; ANTI-INFLAMMATORY AGENTS; ATP BINDING CASSETTE TRANSPORTER 1; CELL LINE; CHOLESTEROL; DIABETIC NEPHROPATHIES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSIDES; HUMANS; INFLAMMATION MEDIATORS; KIDNEY; LIVER X RECEPTORS; NEPHRITIS; ORPHAN NUCLEAR RECEPTORS; PPAR ALPHA; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 84941249154     PISSN: None     EISSN: 11778881     Source Type: Journal    
DOI: 10.2147/DDDT.S90201     Document Type: Article

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