The anti-inflammation effect of Moutan Cortex on advanced glycation end products-induced rat mesangial cells dysfunction and High-glucose-fat diet and streptozotocin-induced diabetic nephropathy rats

Journal of Ethnopharmacology

Volumn 151, Issue 1, 2014, Pages 591-600

  Zhang, Ming Hua ^a,b   Feng, Liang ^a   Zhu, Mao Mao ^a,c   Gu, Jun Fei ^a,d   Jiang, Jun ^a,c,d   Cheng, Xu Dong ^a,d   Ding, Shu Ming ^a,d   Wu, Chan ^a,d   Jia, Xiao Bin ^a,b,d  

^a KEY LABORATORY OF NEW DRUG DELIVERY SYSTEM OF CHINESE MATERIA MEDICA   (China)

^b JIANGSU UNIVERSITY   (China)

^c Nanjing Institute of Supervision and Testing on Product Quality   (China)

^d NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

AGEs; Diabetic nephropathy; Inflammation; Moutan cortex; Rage

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CREATININE; GLUCOSE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PAEONIA SUFFRUTICOSA EXTRACT; PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOSE RESPONSE; DOWN REGULATION; DRUG BLOOD LEVEL; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; GLUCOSE INTAKE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; KIDNEY PARENCHYMA; LIPID DIET; MACROPHAGE; MACROPHAGE MIGRATION; MALE; MESANGIUM CELL; MOUSE; NONHUMAN; PAEONIA SUFFRUTICOSA; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; RAT; STREPTOZOTOCIN-INDUCED DIABETIC NEUROPATHY; SUPERNATANT; WESTERN BLOTTING;

PAEONIA SUFFRUTICOSA; RATTUS;

ADVANCED GLYCATION END PRODUCTS; AG; AGES; AMINOGUANIDINE; BOVINE SERUM ALBUMIN; BSA; DIABETIC NEPHROPATHY; DMEM; DN; DULBECCO'S MODIFIED EAGLE'S MEDIUM; FBS; FETAL BOVINE SERUM; ICAM-1; IL-6; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; MC; MCP-1; MONOCYTE CHEMOATTRACTANT PROTEIN-1; MOUTAN CORTEX; OD; OPTICAL DENSITY; OS; OXIDATIVE STRESS; PBS; PHOSPHATE BUFFERED SALINE; RAGE; REACTIVE OXYGEN SPECIES; RECEPTOR FOR AGES; ROS; SD; STANDARD DEVIATION; STREPTOZOTOCIN; STZ; TGF-Β1; TRANSFORMING GROWTH FACTOR BETA1;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DIETARY FATS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION; GLUCOSE; GLYCOSYLATION END PRODUCTS, ADVANCED; MESANGIAL CELLS; PAEONIA; RANDOM ALLOCATION; RATS;

EID: 84891486237     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.11.015     Document Type: Article

References (63)

1. A. Becker, V.W. Hinsbergh, A. van Jager, P.J. Kostense, J.M. Dekker, G. Nijpels, R.J. Heine, L.M. Bouter, and C.D. Stehouwer Why is soluble intercellular adhesion molecule-1 related to cardiovascular mortality? Eur. J. Clin. Investigation 32 2002 1 8
2. M. Bottner, K. Krieglstein, and K. Unsicker The transforming growth factor-betas: structure, signaling, and roles in nervous system development and functions J. Neurochem. 75 2000 2227 2240
3. J.J. Cha, Y.Y. Hyun, Y.H. Jee, M.J. Lee, K.H. Han, Y.S. Kang, S.Y. Han, and D.R. Cha Plasma concentration of soluble intercellular adhesion molecule-1 (sicam-1) is elevated in Type 2 diabetic patients, and sICAM-1 Synthesis is Associated with Leptin-Induced Activation of the Mitogen-Activated Protein Kinase (MAPK) pathway. Inflammation 36 2013 878 887
4. S. Chen, B. Jim, and F.N. Ziyadeh Diabetic nephropathy and transforming growth factor-β: transforming our view of glomerulosclerosis and fibrosis build-up Semin. Nephrol. 23 2003 532 543
5. Y.X. Cheng, L.L. Zhou, Y.M. Yan, K.X. Chen, and F.F. Hou Diabetic nephropathy-related active cyclic peptides from the roots of Brachystemma calycinum Bioorganic Med. Chemi. Lett. 21 2011 7434 7439
6. F.Y. Chow, D.J. Nikolic-Paterson, E. Ozols, R.C. Atkins, B.J. Rollin, and G.H. Tesch Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated mice Kidney Int. 69 2006 73 80
7. S.C. Chun, S.Y. Jee, S.G. Lee, S.J. Park, J.R. Lee, and S.C. Kim Anti-inflammatory activity of the methanol extract of moutan cortex in LPS-activated Raw264.7 cells Evidence-based Complementary Alternative Med. 4 2007 327 333
8. M.E. Cooper Interaction of metabolic and haemodynamic factors in mediating experimental diabetic nephropathy J. Diabetologia 44 2001 1957 1972
9. M.E. Cooper, P. Mundel, and G. Boner Role of nephrin in renal disease including diabetic nephropathy Semin. Nephrol. 22 2002 393 398
10. M.T. Coughlan, D.R. Thorburn, S.A. Penfold, A Laskowski, B.E Harcourt, K.C. Sourris, A.L. Tan, K. Fukam, V. Thallas-Bonke, P.P. Nawroth, W. Brownlee, A. Bierhaus, M.E. Cooper, and J.M. Forbes RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes J. Am. Soc. Nephrol. 20 2009 742 752
11. S. Doublier, G. Salvidio, E. Lupia, V. Ruotsalainen, D. Verzola, G. Deferrari, and G. Camussi Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin II Diabetes 52 2003 1023 1030
12. L. Ferrucci, T.B. Harris, J.M. Guralnik, R.P. Tracy, M.C. Corti, H.J. Cohen, B. Penninx, M. Pahor, R. Wallace, and R.J. Havlik Serum IL-6 level and the development of disability in older persons J. Am. Geriatrics Soc. 47 1999 639 646
13. J.L. Figarola, N. Shanmugam, R. Natarajan, and S. Rahbar Anti-inflammatory effects of the advanced glycation end product inhibitor LR-90 in human mono-cytes Diabetes 56 2007 647 655
14. H.M. Findeisen, K.J. Pearson, F. Gizard, Y. Zhao, H. Qing, K.L. Jones, D. Cohn, E.B. Heywood, R. de Cabo, and D. Bruemmer Oxidative stress accumulates in adipose tissue during aging and inhibits adipogenesis PLoS One 6 2011 e18532
15. J.M. Forbes, V. Thallas, M.C. Thomas, H.W. Founds, W.C. Burns, G. Jerums, and M.E. Cooper The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes FASEB J. 17 2003 1762 1764
16. C.S. Fox, M.G. Larson, E.P. Leip, J.B. Meigs, P.W. Wilson, and D. Levy Glycemic status and development of kidney disease: the Framingham heart study J. Diabetes Care 28 2005 2436 2440
17. L.E. Fridlyand, and L.H. Philipson Oxidative reactive species in cell injury: mechanisms in diabetes mellitus and therapeutic approaches Ann. New Tork Acad. Sci. 1066 2005 136 151
18. K. Fukami, S. Ueda, S. Yamagishi, S. Kato, Y. Inagaki, M. Takeuchi, Y. Motomiya, R. Bucala, S. Iida, K. Tamaki, T. Imaizumi, M.E. Cooper, and S. Okuda AGEs activate mesangial TGF-β-Smad signaling via an angiotensin II type I receptor interaction Kidney Int. 66 2004 2137 2147
19. K. Fukami, S. Yamagishi, S. Ueda, and S. Okuda Role of AGEs in diabetic nephropathy Curr. Pharma. Design 14 2008 946 952
20. O. García-Sánchez, F.J. López-Hernández, and J.M. López-Novoa An integrative view on the role of TGF-beta in the progressive tubular deletion associated with chronic kidney disease Kidney Int. 77 2012 950 955
21. F. Giacco, and M. Brownlee Oxidative stress and diabetic complications Circ. Res. 107 2010 1058 1070
22. A. Goldin, J.A. Beckman, A.M. Schmidt, and M.A. Creager Advanced glycation end products: sparking the development of diabetic vascular injury Circulation 114 2006 597 605
23. Z.J. Guo, H.X. Niu, F.F. Hou, L. Zhang, N. Fu, R. Nagai, X. Lu, B.H. Chen, Y.X. Shan, J.W. Tian, R.H. Nagaraj, D. Xie, and X. Zhang Advanced oxidation proteinproducts activate vascular endothelial cells via a RAGE-mediated signaling pathway Antioxid Redox Signal 10 2008 1699 1712
24. D. Hendig, L. Tarnow, J. Kuhn, K. Kleesiek, and C. Götting Identification of a xylosyltransferase II gene haplotype marker for diabetic nephropathy in type 1 diabetes Clinica Chimica Acta 398 2008 90 94
25. Q. Hu, B. Li, R. Xu, D. Chen, C. Mu, E. Fei, and G. Wang The protease omi cleaves the mitogen-activated protein kinase kinase MEK1 to inhibit microglial activation Sci. Signal. 5 2012 ra61
26. W.J. Jeffcoate, F. Game, and P.R. Cavanagh The role of proinflammatory cytokines in the cause of neuropathic osteoarthropathy (acute Charcot foot) in diabetes Lancet 366 2005 2058 2061
27. S.O. Jeong, G.S. Oh, H.Y. Ha, B. Soon Koo, H. Sung Kim, Y.C. Kim, E.C. Kim, K.M. Lee, H.T. Chung, and H.O. Pae Dimethoxycurcumin, a synthetic curcumin analogue, induces heme oxygenase-1 expression through Nrf2 activation in RAW264.7 macrophages J. Clini. Biochem. Nutr. 44 2009 79 84
28. S. JJiang, Y. Nakano, R. Yatsuzuka, R. Ono, and C. Kamei Inhibitory effects of Moutan cortex on immediate allergic reactions Biolog. Pharma. Bul. 30 2007 1707 1710
29. S. Kagami, M. Urushihara, A. Kitamura, S. Kondo, T. Hisayama, M. Kitamura, K. Loster, W. Reutter, and Y. Kuroda PDGF-BB enhances alpha1 beta1 integrin-mediated activation of the ERK/AP-1 pathway involved in collagen matrix remodeling by rat mesangial cells J. Cell. Physiol. 198 2004 470 478
30. S. Kato, V.A. Luyckx, M. Ots, K.W. Lee, F. Ziai, J.L. Troy, B.M. Brenner, and H.S. MacKenzie Renin-angiotensin blockade lowers MCP-1 expression in diabetic rats Kidney Int. 56 1999 1037 1048
31. R.G. Langham, D.J. Kelly, R.M. Gow, Y. Zhang, D.J. Cordonnier, N. Pinel, P. Zaoui, and R.E. Gilbert Transforming growth factor-beta in human diabetic nephropathy: effects of ACE inhibition Diabetes Care 29 2006 2670 2675
32. L. Lin, S. Park, and E.G. Lakatta RAGE signaling in inflammation and arterial aging Frontiers Biosci. 14 2009 1403 1413
33. Y. Li, S. Liu, Z. Zhang, Q. Xu, F. Xie, J. Wang, S. Ping, C. Li, Z. Wang, M. Zhang, J. Huang, D. Chen, L. Hu, and C. Li RAGE mediates accelerated diabetic vein graft atherosclerosis induced by combined mechanical stress and AGEs via synergistic ERK activation PLoS One 7 2012 e35016
34. C. Melcion, L. Lachman, and P.D. Killen Mesangial cells, effect of monocyte products on proliferation and matrix synthesis Transplant. Proc. 14 1982 559 564
35. A.A. Mohamed, L. Rashed, H. Amin, M. Abu-Farha, S. Abu El Fadl, and S. Pakhoum K469E polymorphism of the intercellular adhesion molecule-1 gene in Egyptians with coronary heart disease Ann. Saudi Med. 30 2010 432 436
36. P. Mundel, and J. Reiser Proteinuria: an enzymatic disease of the podocyte? Kidney Int. 77 2010 571 580
37. S. Nakamura, H. Li, A. Adijiang, M. Pischetsrieder, and T. Niwa Pyridoxal phosphate prevents progression of diabetic nephropathy Nephrol. Dialysis Transplant. 22 2007 2165 2174
38. T. Nasu, Y Maeshima, M. Kinomura, K. Hirokoshi-Kawahara, K. Tanabe, H. Sugiyama, H. Sonoda, Y. Sato, and H. Makino Vasohibin-1, a negative feedback regulator of angiogenesis, ameliorates renal alterations in a mouse model of diabetic nephropathy Diabetes 58 2009 2365 2375
39. J.F. Navarro, and C. Mora Role of inflammation in diabetic complications Nephrol. Dialysis Transplant. 20 2005 2601 2604
40. J.F. Navarro-Gonzalez, C. Mora-Fernandez, M.M. de Fuentes, and J. Garcia-Perez Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy Nat. Rev. Nephrol. 7 2011 327 340
41. J.F. Navarro, C. Mora, M. Maca, and J. Garca Inflammatory parameters are independently associated with urinary albumin in type 2 diabetes mellitus Am. J. Kidney Dis. 42 2003 53 61
42. M. Neeper, A.M. Schmidt, J. Brett, S.D. Yan, F. Wang, Y.C. Pan, K. Elliston, D. Stern, and A. Shaw Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins J. Biolog. Chem. 267 1992 14998 15004
43. H.L. Nienhuis, J. Westra, A.J. Smit, P.C. Limburg, C.G. Kallenberg, and M. Bijl AGE and their receptor RAGE in systemic autoimmune diseases: an inflammation propagating factor contributing to accelerated atherosclerosis Autoimmunity 42 2009 302 304
44. G. Orasanu, and J. Plutzky The pathologic continuum of diabetic vascular disease J. Am. Coll. Cardiol. 53 2009 S35 S42
45. TY. Poon, KL. Ong, and BM. Cheung Review of the effects of the traditional Chinese medicine rehmannia six formula on diabetes mellitus and its complications 3 2011 184 200 J. Diabetes 3 2011 184 200
46. W. Qi, X. Chen, T.S. Polhill, S. Sumual, S. Twigg, R.E. Gilbert, and C.A. Pollock TGF-beta1 induces IL-8 and MCP-1 through a connective tissue growth factor-independent pathway Am. J. Physiol. Renal Physiol. 290 2006 F703 F709
47. R. Ramasamy, S.F. Yan, and A.M. Schmidt Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications Ann. NY. Acad. Sci. 1243 2011 88 102
48. A. Rivero, C. Mora, M. Muros, J. Garcia, H. Herrera, and J.F. Navarro-Gonzalez Pathogenic perspectives for the role of inflammation in diabetic nephropathy Clin. Sci. 116 2009 479 492
49. J.A. Royall, R.L. Berkow, J.S. Beckman, M.K. Cunningham, S. Matalon, and B.A. Freeman Tumor necrosis factor and interleukin 1 alpha increase vascular endothelial permeability Am. J. Physiol. 257 1989 L399 L410
50. M. Samra, and A.C. Abcar False estimates of elevated creatinine Permanente J. 16 2012 51 52
51. C. Sassy-Prigent, D. Heudes, and C. Mandet Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats Diabetes 49 2000 466 475
52. D. Scieglinska, W. Piglowski, M. Chekan, A. Mazurek, and Z. Krawczyk Differential expression of HSPA1 and HSPA2 proteins in human tissues; tissue microarray-based immunohistochemical study Histochem. Cell Biol. 135 2011 337 350
53. G. Sengoelge, M. Födinger, S. Skoupy, I. Ferrara, C. Zangerle, M. Rogy, W.H. Hörl, G. Sunder-Plassmann, and J. Menzel Endothelial cell adhesion molecule and PMNL response to inflammatory stimuli and AGE-modified fibronectin Kidney Int. 54 1998 1637 1651
54. W.I. Sivitz, and M.A. Yorek Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities Antioxid. Redox Signal. 12 2010 537 577
55. T. Soulis, V. Thallas, S. Youssef, R.E. Gilbert, B.G. McWilliam, R.P. Murray-McIntosh, and M.E. Cooper Advanced glycation end products and their receptors co-localise in rat organs susceptible to diabetic microvascular injury Diabetologia 40 1997 619 628
56. C. Tanifuji, Y. Suzuki, W.M. Geot, S. Horikoshi, T. Sugaya, M. Ruiz-Ortega, J. Egido, and Y. Tomino Reactive oxygen species-mediated signaling pathways in angiotensin II-induced MCP-1 expression of proximal tubular cells Antioxid. Redox Signal. 7 2005 1261 1268
57. V. Vallon The proximal tubule in the pathophysiology of the diabetic kidney Am. J. Physiol.-regulatory Integrative Comparative Physiol. 300 2011 R1009 R1022
58. L. Webster, E.A. Abordo, P.J. Thornalley, and G.A. Limb Induction of TNF-alpha and IL-1beta mRNA in monocytes by methylglyoxal-and advanced glycated end product-modified human serum albumin Biochemical Society Transactions 25 1997 250S
59. M.J. Wu, and Z.Y. Gu Screening of bioactive compounds from Moutan Cortex and their anti-inflammatory activities in rat synoviocytes Evidence-Based Complementary Alternative Med. 6 2009 57 63
60. Y. Xu, S. Wang, L. Feng, Q. Zhu, P. Xiang, and B. He Blockade of PKC-beta protects HUVEC from advanced glycation end products induced inflammation Int. Immunopharma. 10 2010 1552 1559
61. S. Yonemoto, T. Machiguchi, K. Nomura, T. Minakata, M. Nanno, and H. Yoshida Correlations of tissue macrophages and cytoskeletal protein expression with renal fibrosis in patients with diabetes mellitus Clin. Exp. Nephrol. 10 2006 186 192
62. C. Zhang, YL. Chi, PY. Wang, YQ. Wang, YX. Zhang, JT. Deng, CJ. Lv, and SY. Xie MiR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2 PLoS One 7 2012 e46090
63. S.Z. Zhong, Q.H. Ge, R. Qu, Q. Li, and S.P. Ma Paeonol attenuates neurotoxicity and ameliorates cognitive impairment induced by d-galactose in ICR mice J. Neurolog. Sci. 277 2009 58 64