-
1
-
-
0008390266
-
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity
-
de Lecea L., et al. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc. Natl. Acad. Sci. U. S. A. 1998, 95(1):322-327.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, Issue.1
, pp. 322-327
-
-
de Lecea, L.1
-
2
-
-
20244380014
-
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
-
Sakurai T., et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 1998, 92(4):573-585.
-
(1998)
Cell
, vol.92
, Issue.4
, pp. 573-585
-
-
Sakurai, T.1
-
3
-
-
84888143202
-
Orexin: pathways to obesity resistance?
-
Butterick T.A., et al. Orexin: pathways to obesity resistance?. Rev. Endocr. Metab. Disord. 2013, 14(4):357-364.
-
(2013)
Rev. Endocr. Metab. Disord.
, vol.14
, Issue.4
, pp. 357-364
-
-
Butterick, T.A.1
-
4
-
-
84864857152
-
Brain orexin promotes obesity resistance
-
Kotz C., et al. Brain orexin promotes obesity resistance. Ann. N.Y Acad. Sci. 2012, 1264:72-86.
-
(2012)
Ann. N.Y Acad. Sci.
, vol.1264
, pp. 72-86
-
-
Kotz, C.1
-
5
-
-
84864627330
-
Orexin A decreases lipid peroxidation and apoptosis in a novel hypothalamic cell model
-
Butterick T.A., et al. Orexin A decreases lipid peroxidation and apoptosis in a novel hypothalamic cell model. Neurosci. Lett. 2012, 524(1):30-34.
-
(2012)
Neurosci. Lett.
, vol.524
, Issue.1
, pp. 30-34
-
-
Butterick, T.A.1
-
6
-
-
84895075249
-
Orexins protect neuronal cell cultures against hypoxic stress: an involvement of Akt signaling
-
Sokolowska P., et al. Orexins protect neuronal cell cultures against hypoxic stress: an involvement of Akt signaling. J. Mol. Neurosci. 2014, 52(1):48-55.
-
(2014)
J. Mol. Neurosci.
, vol.52
, Issue.1
, pp. 48-55
-
-
Sokolowska, P.1
-
7
-
-
84655167918
-
Orexins promote survival of rat cortical neurons
-
Sokolowska P., et al. Orexins promote survival of rat cortical neurons. Neurosci. Lett. 2012, 506(2):303-306.
-
(2012)
Neurosci. Lett.
, vol.506
, Issue.2
, pp. 303-306
-
-
Sokolowska, P.1
-
8
-
-
84876298227
-
Mitigation of murine focal cerebral ischemia by the hypocretin/orexin system is associated with reduced inflammation
-
Xiong X., et al. Mitigation of murine focal cerebral ischemia by the hypocretin/orexin system is associated with reduced inflammation. Stroke 2013, 44(3):764-770.
-
(2013)
Stroke
, vol.44
, Issue.3
, pp. 764-770
-
-
Xiong, X.1
-
9
-
-
84868209611
-
Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia
-
Hu X., et al. Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke 2012, 43(11):3063-3070.
-
(2012)
Stroke
, vol.43
, Issue.11
, pp. 3063-3070
-
-
Hu, X.1
-
10
-
-
84897976299
-
Microglial priming in neurodegenerative disease
-
Perry V.H., Holmes C. Microglial priming in neurodegenerative disease. Nat. Rev. Neurol. 2014, 10(4):217-224.
-
(2014)
Nat. Rev. Neurol.
, vol.10
, Issue.4
, pp. 217-224
-
-
Perry, V.H.1
Holmes, C.2
-
11
-
-
45749151055
-
Brain foods: the effects of nutrients on brain function
-
Gomez-Pinilla F. Brain foods: the effects of nutrients on brain function. Nat. Rev. Neurosci. 2008, 9(7):568-578.
-
(2008)
Nat. Rev. Neurosci.
, vol.9
, Issue.7
, pp. 568-578
-
-
Gomez-Pinilla, F.1
-
12
-
-
84871650203
-
Neuroinflammation and neurodegeneration in overnutrition-induced diseases
-
Cai D. Neuroinflammation and neurodegeneration in overnutrition-induced diseases. Trends Endocrinol. Metab. 2013, 24(1):40-47.
-
(2013)
Trends Endocrinol. Metab.
, vol.24
, Issue.1
, pp. 40-47
-
-
Cai, D.1
-
13
-
-
84855459760
-
Obesity is associated with hypothalamic injury in rodents and humans
-
Thaler J.P., et al. Obesity is associated with hypothalamic injury in rodents and humans. J. Clin. Invest. 2012, 122(1):153-162.
-
(2012)
J. Clin. Invest.
, vol.122
, Issue.1
, pp. 153-162
-
-
Thaler, J.P.1
-
14
-
-
84862928989
-
Saturated fatty acids activate microglia via Toll-like receptor 4/NF-kappaB signalling
-
Wang Z., et al. Saturated fatty acids activate microglia via Toll-like receptor 4/NF-kappaB signalling. Br. J. Nutr. 2012, 107(2):229-241.
-
(2012)
Br. J. Nutr.
, vol.107
, Issue.2
, pp. 229-241
-
-
Wang, Z.1
-
15
-
-
84919847348
-
Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function
-
Valdearcos M., et al. Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function. Cell Rep. 2014, 9:2124-2138.
-
(2014)
Cell Rep.
, vol.9
, pp. 2124-2138
-
-
Valdearcos, M.1
-
16
-
-
0025233694
-
Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus
-
Blasi E., et al. Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus. J. Neuroimmunol. 1990, 27(2-3):229-237.
-
(1990)
J. Neuroimmunol.
, vol.27
, Issue.2-3
, pp. 229-237
-
-
Blasi, E.1
-
17
-
-
72749091486
-
Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons
-
Belsham D.D., et al. Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons. FASEB J. 2009, 23(12):4256-4265.
-
(2009)
FASEB J.
, vol.23
, Issue.12
, pp. 4256-4265
-
-
Belsham, D.D.1
-
18
-
-
84864312233
-
OX2R activation induces PKC-mediated ERK and CREB phosphorylation
-
Guo Y., Feng P. OX2R activation induces PKC-mediated ERK and CREB phosphorylation. Exp. Cell Res. 2012, 318(16):2004-2013.
-
(2012)
Exp. Cell Res.
, vol.318
, Issue.16
, pp. 2004-2013
-
-
Guo, Y.1
Feng, P.2
-
19
-
-
79955601028
-
Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
-
Pike L.S., et al. Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells. Biochim. Biophys. Acta 2011, 1807(6):726-734.
-
(2011)
Biochim. Biophys. Acta
, vol.1807
, Issue.6
, pp. 726-734
-
-
Pike, L.S.1
-
20
-
-
78651300299
-
TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules
-
Matsunaga N., et al. TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules. Mol. Pharmacol. 2011, 79(1):34-41.
-
(2011)
Mol. Pharmacol.
, vol.79
, Issue.1
, pp. 34-41
-
-
Matsunaga, N.1
-
21
-
-
70350304545
-
Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model
-
Takashima K., et al. Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model. Br. J. Pharmacol. 2009, 157(7):1250-1262.
-
(2009)
Br. J. Pharmacol.
, vol.157
, Issue.7
, pp. 1250-1262
-
-
Takashima, K.1
-
22
-
-
0027169767
-
A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples
-
536-537
-
Chomczynski P. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques 1993, 15(3):532-534. 536-537.
-
(1993)
Biotechniques
, vol.15
, Issue.3
, pp. 532-534
-
-
Chomczynski, P.1
-
23
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25(4):402-408.
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
24
-
-
0032513269
-
Palmitic acid is associated with halorhodopsin as a free fatty acid. Radiolabeling of halorhodopsin with 3H-palmitic acid and chemical analysis of the reaction products of purified halorhodopsin with thiols and NaBH4
-
Colella M., et al. Palmitic acid is associated with halorhodopsin as a free fatty acid. Radiolabeling of halorhodopsin with 3H-palmitic acid and chemical analysis of the reaction products of purified halorhodopsin with thiols and NaBH4. Biochim. Biophys. Acta 1998, 1370(2):273-279.
-
(1998)
Biochim. Biophys. Acta
, vol.1370
, Issue.2
, pp. 273-279
-
-
Colella, M.1
-
25
-
-
15244350494
-
Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand
-
Taylor D.L., et al. Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand. J. Neurosci. 2005, 25(11):2952-2964.
-
(2005)
J. Neurosci.
, vol.25
, Issue.11
, pp. 2952-2964
-
-
Taylor, D.L.1
-
26
-
-
54949148770
-
Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway
-
Pais T.F., et al. Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway. J. Neuroinflammation 2008, 5:43.
-
(2008)
J. Neuroinflammation
, vol.5
, pp. 43
-
-
Pais, T.F.1
-
27
-
-
78649976052
-
Microglial interactions with synapses are modulated by visual experience
-
Tremblay M.E., Lowery R.L., Majewska A.K. Microglial interactions with synapses are modulated by visual experience. PLoS Biol. 2010, 8(11):e1000527.
-
(2010)
PLoS Biol.
, vol.8
, Issue.11
, pp. e1000527
-
-
Tremblay, M.E.1
Lowery, R.L.2
Majewska, A.K.3
-
28
-
-
65249157852
-
Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals
-
Wake H., et al. Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J. Neurosci. 2009, 29(13):3974-3980.
-
(2009)
J. Neurosci.
, vol.29
, Issue.13
, pp. 3974-3980
-
-
Wake, H.1
-
29
-
-
84908651577
-
Obesity and neuroinflammation: a pathway to cognitive impairment
-
Miller A.A., Spencer S.J. Obesity and neuroinflammation: a pathway to cognitive impairment. Brain Behav. Immun. 2014, 42:10-21.
-
(2014)
Brain Behav. Immun.
, vol.42
, pp. 10-21
-
-
Miller, A.A.1
Spencer, S.J.2
-
30
-
-
84924295797
-
Hypothalamic microinflammation: a common basis of metabolic syndrome and aging
-
Tang Y., Purkayastha S., Cai D. Hypothalamic microinflammation: a common basis of metabolic syndrome and aging. Trends Neurosci. 2015, 38(1):36-44.
-
(2015)
Trends Neurosci.
, vol.38
, Issue.1
, pp. 36-44
-
-
Tang, Y.1
Purkayastha, S.2
Cai, D.3
-
31
-
-
84907904248
-
High fat diet induces specific pathological changes in hypothalamic orexin neurons in mice
-
Nobunaga M., et al. High fat diet induces specific pathological changes in hypothalamic orexin neurons in mice. Neurochem. Int. 2014, 78:61-66.
-
(2014)
Neurochem. Int.
, vol.78
, pp. 61-66
-
-
Nobunaga, M.1
-
32
-
-
84899697738
-
2+-dependent PKCalpha and ERK1/2 signals
-
2+-dependent PKCalpha and ERK1/2 signals. PLoS One 2014, 9(4):e95259.
-
(2014)
PLoS One
, vol.9
, Issue.4
, pp. e95259
-
-
Shu, Q.1
-
33
-
-
22244464662
-
ATP mediates rapid microglial response to local brain injury in vivo
-
Davalos D., et al. ATP mediates rapid microglial response to local brain injury in vivo. Nat. Neurosci. 2005, 8(6):752-758.
-
(2005)
Nat. Neurosci.
, vol.8
, Issue.6
, pp. 752-758
-
-
Davalos, D.1
-
34
-
-
19744380563
-
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
Nimmerjahn A., Kirchhoff F., Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005, 308(5726):1314-1318.
-
(2005)
Science
, vol.308
, Issue.5726
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
35
-
-
84875243183
-
Parkinson's disease in the nuclear age of neuroinflammation
-
Nolan Y.M., Sullivan A.M., Toulouse A. Parkinson's disease in the nuclear age of neuroinflammation. Trends Mol. Med. 2013, 19(3):187-196.
-
(2013)
Trends Mol. Med.
, vol.19
, Issue.3
, pp. 187-196
-
-
Nolan, Y.M.1
Sullivan, A.M.2
Toulouse, A.3
-
36
-
-
8544280702
-
Characterization of cellular and neurological damage following unilateral hypoxia/ischemia
-
Olson E.E., McKeon R.J. Characterization of cellular and neurological damage following unilateral hypoxia/ischemia. J. Neurol. Sci. 2004, 227(1):7-19.
-
(2004)
J. Neurol. Sci.
, vol.227
, Issue.1
, pp. 7-19
-
-
Olson, E.E.1
McKeon, R.J.2
-
37
-
-
84858861533
-
Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice
-
Guerrero A.R., et al. Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice. J. Neuroinflammation 2012, 9:40.
-
(2012)
J. Neuroinflammation
, vol.9
, pp. 40
-
-
Guerrero, A.R.1
-
38
-
-
84889095882
-
IL-10 deficiency exacerbates the brain inflammatory response to permanent ischemia without preventing resolution of the lesion
-
Perez-de Puig I., et al. IL-10 deficiency exacerbates the brain inflammatory response to permanent ischemia without preventing resolution of the lesion. J. Cereb. Blood Flow Metab. 2013, 33(12):1955-1966.
-
(2013)
J. Cereb. Blood Flow Metab.
, vol.33
, Issue.12
, pp. 1955-1966
-
-
Perez-de Puig, I.1
-
39
-
-
84891373720
-
Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro
-
Chhor V., et al. Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro. Brain Behav. Immunol. 2013, 32:70-85.
-
(2013)
Brain Behav. Immunol.
, vol.32
, pp. 70-85
-
-
Chhor, V.1
-
41
-
-
84901340197
-
Fractalkine regulation of microglial physiology and consequences on the brain and behavior
-
Paolicelli R.C., Bisht K., Tremblay M.E. Fractalkine regulation of microglial physiology and consequences on the brain and behavior. Front. Cell. Neurosci. 2014, 8:129.
-
(2014)
Front. Cell. Neurosci.
, vol.8
, pp. 129
-
-
Paolicelli, R.C.1
Bisht, K.2
Tremblay, M.E.3
-
42
-
-
84896846872
-
Neuroinflammatory phenotypes and their roles in Alzheimer's disease
-
Wilcock D.M. Neuroinflammatory phenotypes and their roles in Alzheimer's disease. Neuro-degener. Dis. 2013, 13:183-185.
-
(2013)
Neuro-degener. Dis.
, vol.13
, pp. 183-185
-
-
Wilcock, D.M.1
|