Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3)

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 35, 2015, Pages 11018-11023

  Koymans, Kirsten J ^a   Feitsma, Louris J ^b   Brondijk, T Harma C ^b   Aerts, Piet C ^a   Lukkien, Eddie ^b   Lössl, Philip ^b   Van Kessel, Kok P M ^a   De Haas, Carla J C ^a   Van Strijp, Jos A G ^a   Huizinga, Eric G ^b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Crystal structure; Immune evasion; Innate immunity; S. Aureus; Toll like receptor

Indexed keywords

BACTERIAL ANTIGEN; GLYCAN; STAPHYLOCOCCAL SUPERANTIGEN LIKE PROTEIN 3; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 6; UNCLASSIFIED DRUG; ENDOTOXIN; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DIMERIZATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; MUTAGENESIS; PHYSIOLOGY; STAPHYLOCOCCUS AUREUS;

DIMERIZATION; ENDOTOXINS; MOLECULAR STRUCTURE; MUTAGENESIS; PROTEIN BINDING; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTOR 2;

EID: 84941012303     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1502026112     Document Type: Article

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