Staphylococcal superantigen-like protein 10 (SSL10) inhibits blood coagulation by binding to prothrombin and factor Xa via their γ-carboxyglutamic acid (Gla) domain

Journal of Biological Chemistry

Volumn 288, Issue 30, 2013, Pages 21569-21580

  Itoh, Saotomo ^a,b   Yokoyama, Ryosuke ^a   Kamoshida, Go ^b   Fujiwara, Toshinobu ^a   Okada, Hiromi ^a   Takii, Takemasa ^a   Tsuji, Tsutomu ^b   Fujii, Satoshi ^a   Hashizume, Hideki ^c   Onozaki, Kikuo ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b HOSHI UNIVERSITY   (Japan)

^c INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COAGULATION; GLYCOPROTEINS; PROTEINS;

BLOOD COAGULATION; CARBOXYGLUTAMIC ACID; FACTOR XA; NOVEL FUNCTIONS; STRUCTURAL SIMILARITY; SUPERANTIGEN;

BLOOD;

4 CARBOXYGLUTAMIC ACID; BACTERIAL PROTEIN; BINDING PROTEIN; BLOOD CLOTTING FACTOR 10A; CALCIUM ION; COAGULASE; PROTEINASE; PROTHROMBIN; RESIN; SEPHAROSE; STAPHYLOCOCCAL SUPERANTIGEN LIKE PROTEIN 10; STAPHYLOTHROMBIN; UNCLASSIFIED DRUG; WARFARIN;

ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME ACTIVITY; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN ISOLATION; PURIFICATION; STAPHYLOCOCCUS AUREUS; SURFACE PLASMON RESONANCE; SWINE;

EID: 84881245087     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.451419     Document Type: Article

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