Functional basis for complement evasion by staphylococcal superantigen-like 7

Cellular Microbiology

Volumn 12, Issue 10, 2010, Pages 1506-1516

  Bestebroer, Jovanka ^a,d   Aerts, Piet C ^a   Rooijakkers, Suzan H M ^a   Pandey, Manoj K ^b   Köhl, Jörg ^b,c   Van Strijp, Jos A G ^a   De Haas, Carla J C ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF LÜBECK   (Germany)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT; COMPLEMENT COMPONENT C5; COMPLEMENT COMPONENT C5A; FC RECEPTOR; IMMUNOGLOBULIN A; STAPHYLOCOCCAL SUPERANTIGEN LIKE 7; SUPERANTIGEN; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERICIDAL ACTIVITY; CLEARANCE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CYTOLYSIS; ESCHERICHIA COLI; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; MOUSE; NEUTROPHIL; NONHUMAN; OPSONIZATION; PERITONEUM; PERITONITIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN FAMILY; RESPIRATORY BURST; STAPHYLOCOCCUS AUREUS; SURVIVAL;

ANIMALS; BLOOD; COMPLEMENT C5A; DISEASE MODELS, ANIMAL; EXOTOXINS; HUMANS; IMMUNE EVASION; MICE; MICE, INBRED BALB C; PERITONITIS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

ESCHERICHIA COLI; MURINAE; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 78249254568     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2010.01486.x     Document Type: Article

References (39)

1. Al-Shangiti, A.M., Nair, S.P., and Chain, B.M. (2005) The interaction between staphylococcal superantigen-like proteins and human dendritic cells. Clin Exp Immunol 140: 461-469.
2. Arcus, V.L., Langley, R., Proft, T., Fraser, J.D., and Baker, E.N. (2002) The three-dimensional structure of a superantigen-like protein, SET3, from a pathogenicity island of the Staphylococcus aureus genome. J Biol Chem 277: 32274-32281.
3. Bestebroer, J., Poppelier, M.J., Ulfman, L.H., Lenting, P.J., Denis, C.V., Van Kessel, K.P., et al. (2007) Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling. Blood 109: 2936-2943.
4. Beutler, B. (2004) Innate immunity: an overview. Mol Immunol 40: 845-859.
5. Boel, E., Verlaan, S., Poppelier, M.J., Westerdaal, N.A., Van Strijp, J.A., and Logtenberg, T. (2000) Functional human monoclonal antibodies of all isotypes constructed from phage display library-derived single-chain Fv antibody fragments. J Immunol Methods 239: 153-166.
6. Bohnsack, J.F., Widjaja, K., Ghazizadeh, S., Rubens, C.E., Hillyard, D.R., Parker, C.J., et al. (1997) A role for C5 and C5a-ase in the acute neutrophil response to group B streptococcal infections. J Infect Dis 175: 847-855.
7. Cerquetti, M.C., Sordelli, D.O., Ortegon, R.A., and Bellanti, J.A. (1983) Impaired lung defenses against Staphylococcus aureus in mice with hereditary deficiency of the fifth component of complement. Infect Immun 41: 1071-1076.
8. Chavakis, T., Preissner, K.T., and Herrmann, M. (2007) The anti-inflammatory activities of Staphylococcus aureus. Trends Immunol 28: 408-418.
9. Cinader, B., Dubiski, S., and Wardlaw, A.C. (1964) Distribution, inheritance, and properties of an antigen, MuB1, and its relation to hemolytic complement. J Exp Med 120: 897-924.
10. Easmon, C.S., and Glynn, A.A. (1976) Comparison of subcutaneous and intraperitoneal staphylococcal infections in normal and complement-deficient mice. Infect Immun 13: 399-406.
11. Fernandez, H.N., and Hugli, T.E. (1978) Primary structural analysis of the polypeptide portion of human C5a anaphylatoxin. Polypeptide sequence determination and assignment of the oligosaccharide attachment site in C5a. J Biol Chem 253: 6955-6964.
12. Fitzgerald, J.R., Reid, S.D., Ruotsalainen, E., Tripp, T.J., Liu, M., Cole, R., et al. (2003) Genome diversification in Staphylococcus aureus: molecular evolution of a highly variable chromosomal region encoding the Staphylococcal exotoxin-like family of proteins. Infect Immun 71: 2827-2838.
13. Fredslund, F., Laursen, N.S., Roversi, P., Jenner, L., Oliveira, C.L., Pedersen, J.S., et al. (2008) Structure of and influence of a tick complement inhibitor on human complement component 5. Nat Immunol 9: 753-760.
14. Gasque, P. (2004) Complement: a unique innate immune sensor for danger signals. Mol Immunol 41: 1089-1098.
15. Godau, J., Heller, T., Hawlisch, H., Trappe, M., Howells, E., Best, J., et al. (2004) C5a initiates the inflammatory cascade in immune complex peritonitis. J Immunol 173: 3437-3445.
16. De Haas, C.J., Veldkamp, K.E., Peschel, A., Weerkamp, F., Van Wamel, W.J., Heezius, E.C., et al. (2004) Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent. J Exp Med 199: 687-695.
17. Hammel, M., Sfyroera, G., Pyrpassopoulos, S., Ricklin, D., Ramyar, K.X., Pop, M., et al. (2007) Characterization of Ehp, a secreted complement inhibitory protein from Staphylococcus aureus. J Biol Chem 282: 30051-30061.
18. Heller, T., Gessner, J.E., Schmidt, R.E., Klos, A., Bautsch, W., and Kohl, J. (1999a) Cutting edge: Fc receptor type I for IgG on macrophages and complement mediate the inflammatory response in immune complex peritonitis. J Immunol 162: 5657-5661.
19. Heller, T., Hennecke, M., Baumann, U., Gessner, J.E., Zu Vilsendorf, A.M., Baensch, M., et al. (1999b) Selection of a C5a receptor antagonist from phage libraries attenuating the inflammatory response in immune complex disease and ischemia/reperfusion injury. J Immunol 163: 985-994.
20. Hopken, U.E., Lu, B., Gerard, N.P., and Gerard, C. (1996) The C5a chemoattractant receptor mediates mucosal defence to infection. Nature 383: 86-89.
21. Jongerius, I., Kohl, J., Pandey, M.K., Ruyken, M., Van Kessel, K.P., Van Strijp, J.A., and Rooijakkers, S.H. (2007) Staphylococcal complement evasion by various convertase-blocking molecules. J Exp Med 204: 2461-2471.
22. Von Köckritz-Blickwede, M., Konrad, S., Foster, S., Gessner, J.E., and Medina, E. (2009) Protective role of complement C5a in an experimental model of staphylococcus aureus bacteremia. J Innate Immun 2: 87-92.
23. Langley, R., Wines, B., Willoughby, N., Basu, I., Proft, T., and Fraser, J.D. (2005) The staphylococcal superantigen-like protein 7 binds IgA and complement C5 and inhibits IgA-Fc alpha RI binding and serum killing of bacteria. J Immunol 174: 2926-2933.
24. Laursen, N.S., Gordon, N., Hermans, S., Lorenz, N., Jackson, N., Wines, B., et al. (2010) Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus. Proc Natl Acad Sci USA 107: 3681-3686.
25. Mollnes, T.E., Brekke, O.L., Fung, M., Fure, H., Christiansen, D., Bergseth, G., et al. (2002) Essential role of the C5a receptor in E. coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Blood 100: 1869-1877.
26. Monecke, S., Slickers, P., and Ehricht, R. (2008) Assignment of Staphylococcus aureus isolates to clonal complexes based on microarray analysis and pattern recognition. FEMS Immunol Med Microbiol 53: 237-251.
27. Mullaly, S.C., and Kubes, P. (2006) The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands. J Immunol 177: 8154-8163.
28. Muller-Eberhard, H.J. (1986) The membrane attack complex of complement. Annu Rev Immunol 4: 503-528.
29. Pangburn, M.K., and Rawal, N. (2002) Structure and function of complement C5 convertase enzymes. Biochem Soc Trans 30: 1006-1010.
30. Ramsland, P.A., Willoughby, N., Trist, H.M., Farrugia, W., Hogarth, P.M., Fraser, J.D., and Wines, B.D. (2007)Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1. Proc Natl Acad Sci USA 104: 15051-15056.
31. Ricklin, D., and Lambris, J.D. (2007) Complement-targeted therapeutics. Nat Biotechnol 25: 1265-1275.
32. Rooijakkers, S.H., and Van Strijp, J.A. (2007) Bacterial complement evasion. Mol Immunol 44: 23-32.
33. Rooijakkers, S.H., Ruyken, M., Roos, A., Daha, M.R., Presanis, J.S., Sim, R.B., et al. (2005) Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases. Nat Immunol 6: 920-927.
34. Rooijakkers, S.H., Ruyken, M., Van Roon, J., Van Kessel, K.P., Van Strijp, J.A., and Van Wamel, W.J. (2006) Early expression of SCIN and CHIPS drives instant immune evasion by Staphylococcus aureus. Cell Microbiol 8: 1282-1293.
35. Shuiep, E.S., Kanbar, T., Eissa, N., Alber, J., Lammler, C., Zschock, M., et al. (2008) Phenotypic and genotypic characterization of Staphylococcus aureus isolated from raw camel milk samples. Res Vet Sci 86: 211-215.
36. Smyth, D.S., Meaney, W.J., Hartigan, P.J., and Smyth, C.J. (2007) Occurrence of ssl genes in isolates of Staphylococcus aureus from animal infection. J Med Microbiol 56: 418-425.
37. Walenkamp, A.M., Boer, I.G., Bestebroer, J., Rozeveld, D., Timmer-Bosscha, H., Hemrika, W., et al. (2009) Staphylococcal superantigen-like 10 inhibits CXCL12-induced human tumor cell migration. Neoplasia 11: 333-344.
38. Walport, M.J. (2001) Complement. First of two parts. N Engl J Med 344: 1058-1066.
39. Wiesmann, C., Katschke, K.J., Yin, J., Helmy, K.Y., Steffek, M., Fairbrother, W.J., et al. (2006) Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature 444: 217-220.