Global analysis of chemical constituents in Shengmai injection using high performance liquid chromatography coupled with tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 117, Issue , 2016, Pages 61-72

  Li, Fei ^a   Cheng, Tao fang ^a   Dong, Xin ^a   Li, Ping ^a   Yang, Hua ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

HPLC MS; Identification; Quality control; Quantification; Shengmai injection

Indexed keywords

CHINESE DRUG; GINSENOSIDE; LEVO BORNEOL 7 O [BETA DEXTRO APIO FURANOSYL (1-6)] BETA DEXTRO GLUCOPYRANOSIDE; LEVO BORNEOL 7 O [BETA DEXTRO APIO FURANOSYL (1-6)] BETA DEXTRO PYRANOSIDE; OPHIOPOGON ROOT; SAPONIN; SHENGMAI; UNCLASSIFIED DRUG; HERBACEOUS AGENT;

ARTICLE; CHEMICAL COMPOSITION; CHINESE MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUALITY CONTROL; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; CHEMISTRY; FLOW INJECTION ANALYSIS; PROCEDURES;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; FLOW INJECTION ANALYSIS; TANDEM MASS SPECTROMETRY;

EID: 84940864047     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2015.08.022     Document Type: Article

References (26)

1. Zhang X.M., Liu Y. The pharmacological mechanisms and clinical application of shengmai injection. Med. Recapitulate 2013, 19:2813-2816.
2. You J.S., Huang H.F., Chang Y.L., Lee Y.S. Sheng-Mai-San reduces adriamycin-induced cardiomyopathy in rats. Am. J. Chin. Med. 2006, 34:295-305.
3. Chen J., Wu G., Li S., Yu T., Xie Y., Zhou L., Wang L. Shengmai (a traditional Chinese herbal medicine) for heart failure. Cochrane Database Syst. Rev. 2007, 40.
4. Xiang B., Peng Y., Jiang Y.G. A report on the analysis of 365 cases of adverse reactions of Chinese patent drugs for heart cerebrovascular diseases. J. Pharm. Pharmacol. 2013, 20:1267-1271.
5. n. Chin. J. Pharm. Anal. 2013, 33:83-89.
6. Wu F., Sun H., Wei W., Han Y., Wang P., Dong T., Yan G., Wang X. Rapid and global detection and characterization of the constituents in Shengmai San by ultra-performance liquid chromatography-high-definition mass spectrometry. J. Sep. Sci. 2011, 34:3194-3199.
7. Zhang H.J., Wu Y.J., Cheng Y.Y. Analysis of 'SHENMAI' injection by HPLC/MSMS. J. Pharm. Biomed. Anal. 2003, 31:175-183.
8. Wang Q., Zheng X.W., Yu J.D., Liu Y., Dai J.L.U. Establishment of the fingerprint of Shengmai injection and analysis of its main chemical constituents by UPLC-MS/MS. Chin. J. Pharm. Anal. 2012, 32:1813-1817.
9. Zheng C.N., Hao H.P., Wang X., Wu X.L., Wang G.J., Sang G.W., Liang Y., Xie L., Xia C.H., Yao X.L. Diagnostic fragment-ion-based extension strategy for rapid screening and identification of serial components of homologous families contained in traditional Chinese medicine prescription using high-resolution LC-ESI- IT-TOF/MS: Shengmai injection as an example. J. Mass Spectrom. 2009, 44:230-244.
10. Wang J., Zhang P., Tang H.T., Liu H.Q., Tang Y. Simultaneous determination of nine compositions in Shengmai injection by HPLC. Chin. Tradit. Patent Med. 2013, 35:508-512.
11. Xia J., Wang G.L., Ji S., Wang K., Lin R.C. Determination of four components in Shengmai injection by HPLC. Chin. Tradit. Patent Med. 2006, 28:27-31.
12. Yang H., Liu L., Gao W., Liu K., Qi L.W., Li P. Direct and comprehensive analysis of ginsenosides and diterpene alkaloids in Shenfu injection by combinatory liquid chromatography-mass spectrometric techniques. J. Pharm. Biomed. Anal. 2014, 92:13-21.
13. Zhuang J.N., Zhang H., Liu X.F., Zhao L., Zhu Z.Y., Zhang G.Q., Chai Y.F. HPLC-TOF/MS in identification of chemical components in Ginseng. Acad. J. Second Military Med. Univ. 2009, 30:812-816.
14. Qi L.W., Wang H.Y., Zhang H., Wang C.Z., Li P., Yuan C.S. Diagnostic ion filtering to characterize ginseng saponins by rapid liquid chromatography with time-of-flight mass spectrometry. J. Chromatogr. A 2012, 1230:93-99.
15. Chu C., Xu S., Li X., Yan J., Liu L. Profiling the ginsenosides of three ginseng products by LC-Q-TOF/MS. J. Food Sci. 2013, 78:C653-C659.
16. Zhu G.Y., Li Y.W., Hau D.K., Jiang Z.H., Yu Z.L., Fong W.F. Protopanaxatriol-type ginsenosides from the root of Panax ginseng. J. Agric. Food Chem. 2011, 59:200-205.
17. Wan J.Y., Fan Y., Yu Q.T., Ge Y.Z., Yan C.P., Alolga R.N., Li P., Ma Z.H., Qi L.W. Integrated evaluation of malonyl ginsenosides, amino acids and polysaccharides in fresh and processed ginseng. J. Pharm. Biomed. Anal. 2014, 107C:89-97.
18. Zhang H.M., Li S.L., Zhang H., Wang Y., Zhao Z.L., Chen S.L., Xu H.X. Holistic quality evaluation of commercial white and red ginseng using a UPLC-QTOF-MS/MS-based metabolomics approach. J. Pharm. Biomed. Anal. 2012, 62:258-273.
19. Sun H., Wu F., Zhang A., Wei W., Han Y., Wang X. Profiling and identification of the absorbed constituents and metabolites of schisandra lignans by ultra-performance liquid chromatography coupled to mass spectrometry. Biomed. Chromatogr. 2013, 27:1511-1519.
20. Liu M., Zhao S., Wang Z., Wang Y., Liu T., Li S., Wang C., Wang H., Tu P. Identification of metabolites of deoxyschizandrin in rats by UPLC-Q-TOF-MS/MS based on multiple mass defect filter data acquisition and multiple data processing techniques. J. Chromatogr. B Anal. Tech. Biomed. Life Sci. 2014, 949-950:115-126.
21. Wang Y.H., Qiu C., Wang D.W., Hu Z.F., Yu B.Y., Zhu D.N. Identification of multiple constituents in the traditional Chinese medicine formula Sheng-Mai San and rat plasma after oral administration by HPLC-DAD-MS/MS. J. Pharm. Biomed. Anal. 2011, 54:1110-1127.
22. Lan S., Yi F., Shuang L., Wang C.J., Zheng X.W. Chemical constituents from the fibrous root of Ophiopogon japonicus, and their effect on tube formation in human myocardial microvascular endothelial cells. Fitoterapia 2013, 85:57-63.
23. Asano T., Murayama T., Hirai Y., Shoji J. Comparative-studies on the constituents of ophiopogonis tuber and its congeners & studies on the glycosides of the subterranean part of Ophiopogon-japonicus Ker-Gawler cv Nanus. 2. Chem. Pharm. Bull. 1993, 41:566-570.
24. Adinolfi M., Parrilli M., Zhu Y.X. Terpenoid glycosides from Ophiopogon japonicus roots. Phytochemistry 1990, 29:1696-1699.
25. Dai H.F., Zhou J., Deng S.M., Tan N.H. Glycosides from Ophiopogon japonicus. Nat. Prod. Res. Dev. 2000, 12:5-7.
26. Xia L.W., Peng L.P., Yang D.H., Xu L.T. Analysis of constituents in Schisandrae chinensis Fructus by ultra performance liquid chromatography-electrospray ionization time of flight mass spectrometry. Inf. Trad. Chin. Med. 2012, 29:27-30.