메뉴 건너뛰기




Volumn 73, Issue 8, 1999, Pages 7080-7086

Human immunodeficiency virus type 1 Tat protein activates transcription factor NF-κB through the cellular interferon-inducible, double-stranded RNA- dependent protein kinase, PKR

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; INTERFERON; NUCLEAR FACTOR; PROTEIN KINASE; RNA POLYMERASE; TRANSCRIPTION FACTOR; VIRUS PROTEIN;

EID: 0032775261     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.8.7080-7086.1999     Document Type: Article
Times cited : (98)

References (46)
  • 2
    • 0028065074 scopus 로고
    • Effects of human chromosome 12 on interactions between Tat and TAR of human immunodeficiency virus type 1
    • Alonso, A., T. Cujec, and B. Peterlin. 1994. Effects of human chromosome 12 on interactions between Tat and TAR of human immunodeficiency virus type 1. J. Virol. 66:6505-6513.
    • (1994) J. Virol. , vol.66 , pp. 6505-6513
    • Alonso, A.1    Cujec, T.2    Peterlin, B.3
  • 3
    • 0030271387 scopus 로고    scopus 로고
    • NF-κB: Ten years after
    • Baeuerle, P. A., and D. Baltimore. 1996. NF-κB: ten years after. Cell 87:13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 4
    • 0025974973 scopus 로고
    • Cellular factors regulate transactivation of human immunodeficiency virus type 1
    • Barry, P. A., E. Pratt-Lowe, R. E. Unger, and P. A. Luciw. 1991. Cellular factors regulate transactivation of human immunodeficiency virus type 1. J. Virol. 65:1392-1399.
    • (1991) J. Virol. , vol.65 , pp. 1392-1399
    • Barry, P.A.1    Pratt-Lowe, E.2    Unger, R.E.3    Luciw, P.A.4
  • 5
    • 0032544559 scopus 로고    scopus 로고
    • Activation of integrated provirus requires histone acetyltransferase. p300 and P/CAF are coactivators for HIV-1 Tat
    • Benkirane, M., R. F. Chun, H. Xiao, V. V. Ogryzko, B. H. Howard, Y. Nakatani, and K. T. Jeang. 1998. Activation of integrated provirus requires histone acetyltransferase. p300 and P/CAF are coactivators for HIV-1 Tat. J. Biol. Chem. 273:24898-24905.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24898-24905
    • Benkirane, M.1    Chun, R.F.2    Xiao, H.3    Ogryzko, V.V.4    Howard, B.H.5    Nakatani, Y.6    Jeang, K.T.7
  • 6
    • 0025031783 scopus 로고
    • TAR-independent activation of the HIV-1 LTR: Evidence that Tat requires specific regions of the promoter
    • Berkhout, B., A. Gatignol, A. B. Rabson, and K.-T. Jeang. 1990. TAR-independent activation of the HIV-1 LTR: evidence that Tat requires specific regions of the promoter. Cell 62:757-767.
    • (1990) Cell , vol.62 , pp. 757-767
    • Berkhout, B.1    Gatignol, A.2    Rabson, A.B.3    Jeang, K.-T.4
  • 7
    • 0026501088 scopus 로고
    • Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat
    • Berkhout, B., and K. T. Jeang. 1992. Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat. J. Virol. 46:139-149.
    • (1992) J. Virol. , vol.46 , pp. 139-149
    • Berkhout, B.1    Jeang, K.T.2
  • 8
    • 0024322804 scopus 로고
    • Tat trans-activates the human immunodeficiency virus through a nascent RNA target
    • Berkhout, B., R. H. Silverman, and K. T. Jeang. 1989. Tat trans-activates the human immunodeficiency virus through a nascent RNA target. Cell 59:273-282.
    • (1989) Cell , vol.59 , pp. 273-282
    • Berkhout, B.1    Silverman, R.H.2    Jeang, K.T.3
  • 9
    • 0022244511 scopus 로고
    • Purification and substrate specificities of the double-stranded RNA-dependent protein kinase from untreated and interferon treated mouse fibroblasts
    • Berry, M. J., G. S. Knutson, S. R. Lasky, S. M. Munemitsu, and C. E. Samuel. 1985. Purification and substrate specificities of the double-stranded RNA-dependent protein kinase from untreated and interferon treated mouse fibroblasts. J. Biol. Chem. 260:240-247.
    • (1985) J. Biol. Chem. , vol.260 , pp. 240-247
    • Berry, M.J.1    Knutson, G.S.2    Lasky, S.R.3    Munemitsu, S.M.4    Samuel, C.E.5
  • 10
    • 0027332125 scopus 로고
    • Cooperative inhibition of NF-κB and Tat-induced superactivation of human immunodeficiency virus type 1 long terminal repeat
    • Biswas, D. K., C. M. Ahlers, B. J. Dezube, and A. B. Pardee. 1993. Cooperative inhibition of NF-κB and Tat-induced superactivation of human immunodeficiency virus type 1 long terminal repeat. Proc. Natl. Acad. Sci. USA 90:11044-11048.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11044-11048
    • Biswas, D.K.1    Ahlers, C.M.2    Dezube, B.J.3    Pardee, A.B.4
  • 11
    • 0028971304 scopus 로고
    • A Tat-induced auto-up-regulatory loop superactivation of the human immunodeficiency virus type 1 promoter
    • Biswas, D. K., T. R. Salas, F. Wang, C. M. Ahlers, B. J. Dezube, and A. B. Pardee. 1995. A Tat-induced auto-up-regulatory loop superactivation of the human immunodeficiency virus type 1 promoter. J. Virol. 69:7437-7444.
    • (1995) J. Virol. , vol.69 , pp. 7437-7444
    • Biswas, D.K.1    Salas, T.R.2    Wang, F.3    Ahlers, C.M.4    Dezube, B.J.5    Pardee, A.B.6
  • 12
    • 0030928832 scopus 로고    scopus 로고
    • The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR
    • Brand, S. R., R. Kobayashi, and M. B. Mathews. 1997. The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR. J. Biol. Chem. 272:8388-8395.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8388-8395
    • Brand, S.R.1    Kobayashi, R.2    Mathews, M.B.3
  • 13
    • 0030856701 scopus 로고    scopus 로고
    • The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II
    • Cujec, T. P., H. Okamoto, K. Fujinaga, J. Meyer, H. Chamberlin, D. O. Morgan, and B. M. Peterlin. 1997. The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II. Genes Dev. 11:2645-2657.
    • (1997) Genes Dev. , vol.11 , pp. 2645-2657
    • Cujec, T.P.1    Okamoto, H.2    Fujinaga, K.3    Meyer, J.4    Chamberlin, H.5    Morgan, D.O.6    Peterlin, B.M.7
  • 14
    • 0027191817 scopus 로고
    • Does HIV-1 Tat induce a change in viral initiation rights?
    • Cullen, B. 1993. Does HIV-1 Tat induce a change in viral initiation rights? Cell 73:417-420.
    • (1993) Cell , vol.73 , pp. 417-420
    • Cullen, B.1
  • 15
    • 0030001108 scopus 로고    scopus 로고
    • Chronic human immunodeficiency virus type 1 infection of myeloid cells disrupts the autoregulatory control of the NF-κB/Rel pathway via enhanced IκBα degradation
    • DeLuca, C., A. Roulston, A. Koromilas, M. A. Wainberg, and J. Hiscott. 1996. Chronic human immunodeficiency virus type 1 infection of myeloid cells disrupts the autoregulatory control of the NF-κB/Rel pathway via enhanced IκBα degradation. J. Virol. 70:5183-5193.
    • (1996) J. Virol. , vol.70 , pp. 5183-5193
    • DeLuca, C.1    Roulston, A.2    Koromilas, A.3    Wainberg, M.A.4    Hiscott, J.5
  • 16
    • 0029940987 scopus 로고    scopus 로고
    • Activation of transcription factor NF-κB by the Tat protein of human immunodeficiency virus type 1
    • Demarchi, F., F. d'Adda di Fagagna, A. Falaschi, and M. Giacca. 1996. Activation of transcription factor NF-κB by the Tat protein of human immunodeficiency virus type 1. J. Virol. 70:4427-4437.
    • (1996) J. Virol. , vol.70 , pp. 4427-4437
    • Demarchi, F.1    D'Adda Di Fagagna, F.2    Falaschi, A.3    Giacca, M.4
  • 17
    • 0027360912 scopus 로고
    • In vivo foot-printing analysis of constitutive and inducible protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1
    • Demarchi, F., P. D'Agaro, A. Falaschi, and M. Giacca. 1993. In vivo foot-printing analysis of constitutive and inducible protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1. J. Virol. 67:7450-7460.
    • (1993) J. Virol. , vol.67 , pp. 7450-7460
    • Demarchi, F.1    D'Agaro, P.2    Falaschi, A.3    Giacca, M.4
  • 18
    • 0024576640 scopus 로고
    • Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: A novel translalional control mechanism
    • Edery, I., R. Petryshyn, and N. Sonenberg. 1989. Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: a novel translalional control mechanism. Cell 56:303-312.
    • (1989) Cell , vol.56 , pp. 303-312
    • Edery, I.1    Petryshyn, R.2    Sonenberg, N.3
  • 19
    • 0031942998 scopus 로고    scopus 로고
    • Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter
    • El Kharroubi, A., G. Piras, R. Zensen, and M. A. Martin. 1998. Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. Mol. Cell. Biol. 18:2535-2544.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2535-2544
    • El Kharroubi, A.1    Piras, G.2    Zensen, R.3    Martin, M.A.4
  • 20
    • 0023860379 scopus 로고
    • A quantitative bioassay for HIV-1 based on trans-activation
    • Felber, B. K., and G. N. Pavlakis. 1988. A quantitative bioassay for HIV-1 based on trans-activation. Science 239:184-186.
    • (1988) Science , vol.239 , pp. 184-186
    • Felber, B.K.1    Pavlakis, G.N.2
  • 21
    • 0031958598 scopus 로고    scopus 로고
    • PITALRE, the catalytic subunit of TAK, is required for human immunodeficiency virus Tat transactivation in vivo
    • Gold, M. O., X. Yang, C. H. Herrmann, and A. P. Rice. 1998. PITALRE, the catalytic subunit of TAK, is required for human immunodeficiency virus Tat transactivation in vivo. J. Virol. 72:4448-4453.
    • (1998) J. Virol. , vol.72 , pp. 4448-4453
    • Gold, M.O.1    Yang, X.2    Herrmann, C.H.3    Rice, A.P.4
  • 22
    • 0026490072 scopus 로고
    • Tat-responsive region RNA of human immunodeficiency virus type 1 stimulates protein synthesis in vivo and in vitro: Relationship between structure and function
    • Gunnery, S., S. R. Green, and M. B. Mathews. 1992. Tat-responsive region RNA of human immunodeficiency virus type 1 stimulates protein synthesis in vivo and in vitro: relationship between structure and function. Proc. Natl. Acad. Sci. USA 89:11557-11561.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11557-11561
    • Gunnery, S.1    Green, S.R.2    Mathews, M.B.3
  • 23
    • 0025228070 scopus 로고
    • Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase
    • Gunnery, S., A. P. Rice, H. D. Robertson, and M. B. Mathews. 1990. Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase. Proc. Natl. Acad. Sci. USA 87:8687-8691.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8687-8691
    • Gunnery, S.1    Rice, A.P.2    Robertson, H.D.3    Mathews, M.B.4
  • 24
    • 0029669994 scopus 로고    scopus 로고
    • Differential effects of IκB molecules on Tat-mediated transactivation of the LTR
    • Harhaj, E., J. Blanley, S. Millhouse, and S. C. Sun. 1996. Differential effects of IκB molecules on Tat-mediated transactivation of the LTR. Virology 216:284-287.
    • (1996) Virology , vol.216 , pp. 284-287
    • Harhaj, E.1    Blanley, J.2    Millhouse, S.3    Sun, S.C.4
  • 25
    • 0025639004 scopus 로고
    • Tar independent activation of the human immunodeficiency virus in phorbol ester stimulated T lymphocytes
    • Harrich, D., J. Garcia, R. Mtsuyasu, and R. Gaynor. 1990. Tar independent activation of the human immunodeficiency virus in phorbol ester stimulated T lymphocytes. EMBO J. 9:4417-4423.
    • (1990) EMBO J. , vol.9 , pp. 4417-4423
    • Harrich, D.1    Garcia, J.2    Mtsuyasu, R.3    Gaynor, R.4
  • 26
    • 0027176524 scopus 로고
    • Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB
    • Henkel, T., T. Machleidt, I. Alkalay, M. Kronke, Y. Ben-Neriah, and P. A. Baeuerle. 1993. Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-KB. Nature 365:182-185.
    • (1993) Nature , vol.365 , pp. 182-185
    • Henkel, T.1    Machleidt, T.2    Alkalay, I.3    Kronke, M.4    Ben-Neriah, Y.5    Baeuerle, P.A.6
  • 27
    • 0031690395 scopus 로고    scopus 로고
    • Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein
    • Hottiger, M. O., and G. J. Nabel. 1998. Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein. J. Virol. 72:8252-8256.
    • (1998) J. Virol. , vol.72 , pp. 8252-8256
    • Hottiger, M.O.1    Nabel, G.J.2
  • 28
    • 0028332026 scopus 로고
    • Double-stranded RNA-dependent protein kinase activates transcription factor NF-κB by phosphorylating IκB
    • Kumar, A., J. Haque, J. Lacoste, J. Hiscott, and B. R. G. Williams. 1994. Double-stranded RNA-dependent protein kinase activates transcription factor NF-κB by phosphorylating IκB. Proc. Natl. Acad. Sci. USA 91:6288-6292.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6288-6292
    • Kumar, A.1    Haque, J.2    Lacoste, J.3    Hiscott, J.4    Williams, B.R.G.5
  • 29
    • 17444449609 scopus 로고    scopus 로고
    • Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: Role of IRF-1 and NF-κB
    • Kumar, A., Y. L. Yang, V. Flati, S. Der, S. Kadereit, A. Deb, J. Haque, L. Reis, C. Weissmann, and B. R. G. Williams. 1997. Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-κB. EMBO J. 16:406-416.
    • (1997) EMBO J. , vol.16 , pp. 406-416
    • Kumar, A.1    Yang, Y.L.2    Flati, V.3    Der, S.4    Kadereit, S.5    Deb, A.6    Haque, J.7    Reis, L.8    Weissmann, C.9    Williams, B.R.G.10
  • 30
    • 0024428086 scopus 로고
    • The NF-κB binding sites in the human immunodeficiency virus type 1 long terminal repeat are not required for virus infectivity
    • Leonard, J., C. Parrott, A. J. Buckler-White, W. Turner, E. K. Ross, M. A. Martin, and A. B. Rabson. 1989. The NF-κB binding sites in the human immunodeficiency virus type 1 long terminal repeat are not required for virus infectivity. J. Virol. 63:4919-4924.
    • (1989) J. Virol. , vol.63 , pp. 4919-4924
    • Leonard, J.1    Parrott, C.2    Buckler-White, A.J.3    Turner, W.4    Ross, E.K.5    Martin, M.A.6    Rabson, A.B.7
  • 31
    • 0026100191 scopus 로고
    • An in vitro transcription analysis of early responses of the human immunodeficiency virus type 1 long terminal repeat to different transcription activators
    • Li, Y., J. Ross, J. A. Scheppler, and R. Franza, Jr. 1991. An in vitro transcription analysis of early responses of the human immunodeficiency virus type 1 long terminal repeat to different transcription activators. Mol. Cell. Biol. 11:1883-1893.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1883-1893
    • Li, Y.1    Ross, J.2    Scheppler, J.A.3    Franza R., Jr.4
  • 32
    • 0026685175 scopus 로고
    • Specific NF-κB subunits act in concert with Tat to stimulate human immunodeficiency type 1 transcription
    • Liu, J., N. Perkins, R. Schmid, and G. Nabel. 1992. Specific NF-κB subunits act in concert with Tat to stimulate human immunodeficiency type 1 transcription. J. Virol. 66:3883-3887.
    • (1992) J. Virol. , vol.66 , pp. 3883-3887
    • Liu, J.1    Perkins, N.2    Schmid, R.3    Nabel, G.4
  • 33
    • 0032506242 scopus 로고    scopus 로고
    • HIV-1 Tat transactivator recruits p300 and CBP histone acetyl transferases to the viral promoter
    • Marzio, G., M. Tyagi, M. I. Gutierrez, and M. Giacca. 1998. HIV-1 Tat transactivator recruits p300 and CBP histone acetyl transferases to the viral promoter. Proc. Natl. Acad. Sci. USA 23:13519-13524.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.23 , pp. 13519-13524
    • Marzio, G.1    Tyagi, M.2    Gutierrez, M.I.3    Giacca, M.4
  • 35
    • 0023818576 scopus 로고
    • Alternative mechanisms for activation of human immunodeficiency virus enhancer in T cells
    • Nabel, G. J., S. A. Rice, D. M. Knipe, and D. Baltimore. 1988. Alternative mechanisms for activation of human immunodeficiency virus enhancer in T cells. Science 239:1299-1302.
    • (1988) Science , vol.239 , pp. 1299-1302
    • Nabel, G.J.1    Rice, S.A.2    Knipe, D.M.3    Baltimore, D.4
  • 36
    • 0029956642 scopus 로고    scopus 로고
    • Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain
    • Parada, C. A., and R. G. Roeder. 1996. Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain. Nature 384:375-378.
    • (1996) Nature , vol.384 , pp. 375-378
    • Parada, C.A.1    Roeder, R.G.2
  • 38
    • 0025267438 scopus 로고
    • Control of the interferon-induced 68-kilodalton protein kinase by the HIV-1 tat gene product
    • Roy, S., M. G. Katze, N. T. Parkin, I. Edery, A. G. Hovanessian, and N. Sonenberg. 1990. Control of the interferon-induced 68-kilodalton protein kinase by the HIV-1 tat gene product. Science 247:1216-1219.
    • (1990) Science , vol.247 , pp. 1216-1219
    • Roy, S.1    Katze, M.G.2    Parkin, N.T.3    Edery, I.4    Hovanessian, A.G.5    Sonenberg, N.6
  • 40
    • 0025739093 scopus 로고
    • Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities
    • Samuel, C. E. 1991. Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology 183:1-11.
    • (1991) Virology , vol.183 , pp. 1-11
    • Samuel, C.E.1
  • 41
    • 0040350202 scopus 로고
    • Mechanism of interferon action. Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase possessing site specificity similar to hemin-regulated rabbit reticulocyte kinase
    • Samuel, C. E. 1979. Mechanism of interferon action. Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase possessing site specificity similar to hemin-regulated rabbit reticulocyte kinase. Proc. Natl. Acad. Sci. USA 76:600-604.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 600-604
    • Samuel, C.E.1
  • 42
    • 3242802984 scopus 로고
    • Rapidly and slowly replicating human immunodeficiency virus type 1 isolates can be distinguished according to target-cell tropism in T-cell and monocyte cell lines
    • Schwartz, S., B. K. Felber, E. M. Fenyo, and G. N. Pavlakis. 1989. Rapidly and slowly replicating human immunodeficiency virus type 1 isolates can be distinguished according to target-cell tropism in T-cell and monocyte cell lines. Proc. Natl. Acad. Sci. USA 86:7200-7203.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 7200-7203
    • Schwartz, S.1    Felber, B.K.2    Fenyo, E.M.3    Pavlakis, G.N.4
  • 43
    • 0032548918 scopus 로고    scopus 로고
    • A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA
    • Wei, P., M. E. Garber, S.-M. Fang, W. H. Fisher, and K. A. Jones. 1998. A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell 92:451-462.
    • (1998) Cell , vol.92 , pp. 451-462
    • Wei, P.1    Garber, M.E.2    Fang, S.-M.3    Fisher, W.H.4    Jones, K.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.