Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium

Autophagy

Volumn 11, Issue 6, 2015, Pages 939-953

  Yao, Jingyu ^a   Jia, Lin ^a   Khan, Naheed ^a   Lin, Chengmao ^a   Mitter, Sayak K ^c   Boulton, Michael E ^c   Dunaief, Joshua L ^b   Klionsky, Daniel J ^d   Guan, Jun Lin ^e   Thompson, Debra A ^a   Zacks, David N ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Age related macular degeneration; FIP200; Photoreceptor; Retina; Retinal pigment epithelium

Indexed keywords

BAFILOMYCIN A1; BETA1 INTEGRIN; CATHEPSIN D; PROTEIN ZO1; UBIQUITIN; RB1CC1 PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BRUCH MEMBRANE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VACUOLE; CONTROLLED STUDY; ELECTRORETINOGRAPHY; EX VIVO STUDY; EYE PHOTOGRAPHY; GENE; GENE DELETION; IMMUNOHISTOCHEMISTRY; IMMUNOSURVEILLANCE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MELANOSOME; MICROGLIA; MOUSE; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; OXIDATIVE STRESS; PHENOTYPE; PHOTORECEPTOR; PHOTORECEPTOR OUTER SEGMENT; PIGMENT EPITHELIUM; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; RB1CC1 GENE; RETINA FLUORESCEIN ANGIOGRAPHY; RETINA NEOVASCULARIZATION; RETINA PIGMENT DEGENERATION; SUBRETINAL NEOVASCULARIZATION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; ANIMAL; EPITHELIUM; GENETICS; METABOLISM; MITOCHONDRION; PROCEDURES; RETINAL PIGMENT EPITHELIUM;

ANIMALS; AUTOPHAGY; ELECTRORETINOGRAPHY; EPITHELIUM; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MITOCHONDRIA; RETINAL PIGMENT EPITHELIUM; SEQUENCE DELETION;

EID: 84940837701     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2015.1041699     Document Type: Article

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