메뉴 건너뛰기




Volumn 37, Issue 8, 2012, Pages 325-332

Eaten alive! Cell death by primary phagocytosis: 'Phagoptosis'

Author keywords

Apoptosis; Cell death; Clearance; Inflammation; Phagocytosis; Turnover

Indexed keywords

CALRETICULIN; CD200 ANTIGEN; CD31 ANTIGEN; CD47 ANTIGEN; COMPLEMENT COMPONENT C1Q; FORMYLPEPTIDE RECEPTOR LIKE 1; LIPOCORTIN 1; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; PADGEM PROTEIN; PHOSPHATIDYLSERINE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN BCL 2; VITRONECTIN RECEPTOR;

EID: 84864322419     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2012.05.002     Document Type: Review
Times cited : (253)

References (72)
  • 1
    • 80755180853 scopus 로고    scopus 로고
    • Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways
    • Ravichandran K.S. Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways. Immunity 2011, 35:445-455.
    • (2011) Immunity , vol.35 , pp. 445-455
    • Ravichandran, K.S.1
  • 2
    • 79960923112 scopus 로고    scopus 로고
    • Neutrophil clearance: when the party is over, clean-up begins
    • Bratton D.L., Henson P.M. Neutrophil clearance: when the party is over, clean-up begins. Trends Immunol. 2011, 32:350-357.
    • (2011) Trends Immunol. , vol.32 , pp. 350-357
    • Bratton, D.L.1    Henson, P.M.2
  • 3
    • 0035846941 scopus 로고    scopus 로고
    • Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts
    • Fadok V.A., et al. Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts. J. Biol. Chem. 2001, 276:1071-1077.
    • (2001) J. Biol. Chem. , vol.276 , pp. 1071-1077
    • Fadok, V.A.1
  • 4
    • 26844468253 scopus 로고    scopus 로고
    • Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte
    • Gardai S.J., et al. Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte. Cell 2005, 123:321-334.
    • (2005) Cell , vol.123 , pp. 321-334
    • Gardai, S.J.1
  • 5
    • 34247235049 scopus 로고    scopus 로고
    • Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: implications for the resolution of inflammation
    • Tyurina Y.Y., et al. Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: implications for the resolution of inflammation. J. Biol. Chem. 2007, 282:8498-8509.
    • (2007) J. Biol. Chem. , vol.282 , pp. 8498-8509
    • Tyurina, Y.Y.1
  • 6
    • 69249091384 scopus 로고    scopus 로고
    • Suicidal membrane repair regulates phosphatidylserine externalization during apoptosis
    • Mirnikjoo B., et al. Suicidal membrane repair regulates phosphatidylserine externalization during apoptosis. J. Biol. Chem. 2009, 284:22512-22516.
    • (2009) J. Biol. Chem. , vol.284 , pp. 22512-22516
    • Mirnikjoo, B.1
  • 7
    • 65449122791 scopus 로고    scopus 로고
    • Mobilization of lysosomal calcium regulates the externalization of phosphatidylserine during apoptosis
    • Mirnikjoo B., et al. Mobilization of lysosomal calcium regulates the externalization of phosphatidylserine during apoptosis. J. Biol. Chem. 2009, 284:6918-6923.
    • (2009) J. Biol. Chem. , vol.284 , pp. 6918-6923
    • Mirnikjoo, B.1
  • 8
    • 0346100680 scopus 로고    scopus 로고
    • Phosphatidylserine expression and phagocytosis of apoptotic thymocytes during differentiation of monocytic cells
    • Callahan M.K., et al. Phosphatidylserine expression and phagocytosis of apoptotic thymocytes during differentiation of monocytic cells. J. Leukoc. Biol. 2003, 74:846-856.
    • (2003) J. Leukoc. Biol. , vol.74 , pp. 846-856
    • Callahan, M.K.1
  • 9
    • 0142103332 scopus 로고    scopus 로고
    • Dimeric galectin-1 induces surface exposure of phosphatidylserine and phagocytic recognition of leukocytes without inducing apoptosis
    • Dias-Baruffi M., et al. Dimeric galectin-1 induces surface exposure of phosphatidylserine and phagocytic recognition of leukocytes without inducing apoptosis. J. Biol. Chem. 2003, 278:41282-41293.
    • (2003) J. Biol. Chem. , vol.278 , pp. 41282-41293
    • Dias-Baruffi, M.1
  • 10
    • 23144448574 scopus 로고    scopus 로고
    • Membrane phosphatidylserine distribution as a nonapoptotic signaling mechanism in lymphocytes
    • Elliott J.I., et al. Membrane phosphatidylserine distribution as a nonapoptotic signaling mechanism in lymphocytes. Nat. Cell Biol. 2005, 7:808-816.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 808-816
    • Elliott, J.I.1
  • 11
    • 33845512042 scopus 로고    scopus 로고
    • Antigen recognition induces phosphatidylserine exposure on the cell surface of human CD8+ T cells
    • Fischer K., et al. Antigen recognition induces phosphatidylserine exposure on the cell surface of human CD8+ T cells. Blood 2006, 108:4094-4101.
    • (2006) Blood , vol.108 , pp. 4094-4101
    • Fischer, K.1
  • 12
    • 34547138164 scopus 로고    scopus 로고
    • Regulated externalization of phosphatidylserine at the cell surface: implications for apoptosis
    • Balasubramanian K., et al. Regulated externalization of phosphatidylserine at the cell surface: implications for apoptosis. J. Biol. Chem. 2007, 282:18357-18364.
    • (2007) J. Biol. Chem. , vol.282 , pp. 18357-18364
    • Balasubramanian, K.1
  • 13
    • 65249141172 scopus 로고    scopus 로고
    • Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane
    • Stowell S.R., et al. Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane. Mol. Biol. Cell 2009, 20:1408-1418.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 1408-1418
    • Stowell, S.R.1
  • 14
    • 61449208877 scopus 로고    scopus 로고
    • Induction of caspase- and reactive oxygen species-independent phosphatidylserine externalization in primary human neutrophils: role in macrophage recognition and engulfment
    • Jitkaew S., et al. Induction of caspase- and reactive oxygen species-independent phosphatidylserine externalization in primary human neutrophils: role in macrophage recognition and engulfment. J. Leukoc. Biol. 2009, 85:427-437.
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 427-437
    • Jitkaew, S.1
  • 15
    • 79955008182 scopus 로고    scopus 로고
    • Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death
    • Neher J.J., et al. Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death. J. Immunol. 2011, 186:4973-4983.
    • (2011) J. Immunol. , vol.186 , pp. 4973-4983
    • Neher, J.J.1
  • 16
    • 62049085194 scopus 로고    scopus 로고
    • Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
    • Panaretakis T., et al. Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death. EMBO J. 2009, 28:578-590.
    • (2009) EMBO J. , vol.28 , pp. 578-590
    • Panaretakis, T.1
  • 17
    • 0038756766 scopus 로고    scopus 로고
    • Calreticulin is at the surface of circulating neutrophils and uses CD59 as an adaptor molecule
    • Ghiran I., et al. Calreticulin is at the surface of circulating neutrophils and uses CD59 as an adaptor molecule. J. Biol. Chem. 2003, 278:21024-21031.
    • (2003) J. Biol. Chem. , vol.278 , pp. 21024-21031
    • Ghiran, I.1
  • 18
    • 78650664067 scopus 로고    scopus 로고
    • Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47
    • Chao M.P., et al. Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47. Sci. Transl. Med. 2010, 2:63ra94.
    • (2010) Sci. Transl. Med. , vol.2
    • Chao, M.P.1
  • 19
    • 79952663868 scopus 로고    scopus 로고
    • Investigations on the C1q-calreticulin-phosphatidylserine interactions yield new insights into apoptotic cell recognition
    • Païdassi H., et al. Investigations on the C1q-calreticulin-phosphatidylserine interactions yield new insights into apoptotic cell recognition. J. Mol. Biol. 2011, 408:277-290.
    • (2011) J. Mol. Biol. , vol.408 , pp. 277-290
    • Païdassi, H.1
  • 20
    • 77955873996 scopus 로고    scopus 로고
    • Identification of a human monoclonal natural IgM antibody that recognizes early apoptotic cells and promotes phagocytosis
    • Kim J. Identification of a human monoclonal natural IgM antibody that recognizes early apoptotic cells and promotes phagocytosis. Hybridoma 2010, 29:275-281.
    • (2010) Hybridoma , vol.29 , pp. 275-281
    • Kim, J.1
  • 21
    • 36248987290 scopus 로고    scopus 로고
    • BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module
    • Park D., et al. BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module. Nature 2007, 450:430-434.
    • (2007) Nature , vol.450 , pp. 430-434
    • Park, D.1
  • 22
    • 82755163551 scopus 로고    scopus 로고
    • Constitutive exposure of phosphatidylserine on viable cells
    • Segawa K., et al. Constitutive exposure of phosphatidylserine on viable cells. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:19246-19251.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 19246-19251
    • Segawa, K.1
  • 23
    • 2342500301 scopus 로고    scopus 로고
    • Milk fat globule epidermal growth factor 8 (MFG-E8) binds to oxidized phosphatidylserine: implications for macrophage clearance of apoptotic cells
    • Borisenko G.G., et al. Milk fat globule epidermal growth factor 8 (MFG-E8) binds to oxidized phosphatidylserine: implications for macrophage clearance of apoptotic cells. Cell Death Differ. 2004, 11:943-945.
    • (2004) Cell Death Differ. , vol.11 , pp. 943-945
    • Borisenko, G.G.1
  • 24
    • 18244396105 scopus 로고    scopus 로고
    • Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia
    • Olsson M., et al. Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia. Blood 2005, 105:3577-3582.
    • (2005) Blood , vol.105 , pp. 3577-3582
    • Olsson, M.1
  • 25
    • 0035920515 scopus 로고    scopus 로고
    • CD47 (integrin-associated protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells
    • Blazar B.R., et al. CD47 (integrin-associated protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells. J. Exp. Med. 2001, 194:541-549.
    • (2001) J. Exp. Med. , vol.194 , pp. 541-549
    • Blazar, B.R.1
  • 26
    • 84655167968 scopus 로고    scopus 로고
    • Programmed cell removal: a new obstacle in the road to developing cancer
    • Chao M.P., et al. Programmed cell removal: a new obstacle in the road to developing cancer. Nat. Rev. Cancer 2011, 12:58-67.
    • (2011) Nat. Rev. Cancer , vol.12 , pp. 58-67
    • Chao, M.P.1
  • 27
    • 84856007233 scopus 로고    scopus 로고
    • Sialic acid on the neuronal glycocalyx prevents complement c1 binding and complement receptor-3-mediated removal by microglia
    • Linnartz B., et al. Sialic acid on the neuronal glycocalyx prevents complement c1 binding and complement receptor-3-mediated removal by microglia. J. Neurosci. 2012, 32:946-952.
    • (2012) J. Neurosci. , vol.32 , pp. 946-952
    • Linnartz, B.1
  • 28
    • 77956941695 scopus 로고    scopus 로고
    • Decrease of sialic acid residues as an eat-me signal on the surface of apoptotic lymphocytes
    • Meesmann H.M., et al. Decrease of sialic acid residues as an eat-me signal on the surface of apoptotic lymphocytes. J. Cell Sci. 2010, 123:3347-3356.
    • (2010) J. Cell Sci. , vol.123 , pp. 3347-3356
    • Meesmann, H.M.1
  • 29
    • 77749324852 scopus 로고    scopus 로고
    • Alleviation of neurotoxicity by microglial human Siglec-11
    • Wang Y., Neumann H. Alleviation of neurotoxicity by microglial human Siglec-11. J. Neurosci. 2010, 30:3482-3488.
    • (2010) J. Neurosci. , vol.30 , pp. 3482-3488
    • Wang, Y.1    Neumann, H.2
  • 30
    • 0037938686 scopus 로고    scopus 로고
    • Aminophosphospholipid asymmetry: a matter of life and death
    • Balasubramanian K., Schroit A.J. Aminophosphospholipid asymmetry: a matter of life and death. Annu. Rev. Physiol. 2003, 65:701-734.
    • (2003) Annu. Rev. Physiol. , vol.65 , pp. 701-734
    • Balasubramanian, K.1    Schroit, A.J.2
  • 31
    • 79955953536 scopus 로고    scopus 로고
    • Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver
    • Lee S.J., et al. Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver. Blood 2011, 117:5215-5223.
    • (2011) Blood , vol.117 , pp. 5215-5223
    • Lee, S.J.1
  • 32
    • 78650661684 scopus 로고    scopus 로고
    • TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells
    • Albacker L.A., et al. TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells. J. Immunol. 2010, 185:6839-6849.
    • (2010) J. Immunol. , vol.185 , pp. 6839-6849
    • Albacker, L.A.1
  • 33
    • 84855415055 scopus 로고    scopus 로고
    • Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow
    • Dalli J., et al. Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow. FASEB J. 2011, 26:387-396.
    • (2011) FASEB J. , vol.26 , pp. 387-396
    • Dalli, J.1
  • 34
    • 0035849895 scopus 로고    scopus 로고
    • Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans
    • Hoeppner D.J., et al. Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans. Nature 2001, 412:202-206.
    • (2001) Nature , vol.412 , pp. 202-206
    • Hoeppner, D.J.1
  • 35
    • 0035849886 scopus 로고    scopus 로고
    • Phagocytosis promotes programmed cell death in C. elegans
    • Reddien P., et al. Phagocytosis promotes programmed cell death in C. elegans. Nature 2001, 412:198-202.
    • (2001) Nature , vol.412 , pp. 198-202
    • Reddien, P.1
  • 36
    • 52049105429 scopus 로고    scopus 로고
    • Caenorhabditis elegans genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33
    • Galvin B.D., et al. Caenorhabditis elegans genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33. Genetics 2008, 179:403-417.
    • (2008) Genetics , vol.179 , pp. 403-417
    • Galvin, B.D.1
  • 37
    • 42549152012 scopus 로고    scopus 로고
    • Role of C. elegans TAT-1 protein in maintaining plasma membrane phosphatidylserine asymmetry
    • Darland-Ransom M., et al. Role of C. elegans TAT-1 protein in maintaining plasma membrane phosphatidylserine asymmetry. Science 2008, 320:528-531.
    • (2008) Science , vol.320 , pp. 528-531
    • Darland-Ransom, M.1
  • 38
    • 78650512821 scopus 로고    scopus 로고
    • Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans
    • Neukomm L.J., et al. Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans. Nat. Cell Biol. 2011, 13:79-86.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 79-86
    • Neukomm, L.J.1
  • 39
    • 0346752184 scopus 로고    scopus 로고
    • Caspase-independent cell engulfment mirrors cell death pattern in Drosophila embryos
    • Mergliano J., Minden J.S. Caspase-independent cell engulfment mirrors cell death pattern in Drosophila embryos. Development 2003, 130:5779-5789.
    • (2003) Development , vol.130 , pp. 5779-5789
    • Mergliano, J.1    Minden, J.S.2
  • 40
    • 72449212215 scopus 로고    scopus 로고
    • Pretaporter, a Drosophila protein serving as a ligand for Draper in the phagocytosis of apoptotic cells
    • Kuraishi T., et al. Pretaporter, a Drosophila protein serving as a ligand for Draper in the phagocytosis of apoptotic cells. EMBO J. 2009, 28:3868-3878.
    • (2009) EMBO J. , vol.28 , pp. 3868-3878
    • Kuraishi, T.1
  • 41
    • 34250025633 scopus 로고    scopus 로고
    • Engulfment is required for cell competition
    • Li W., Baker N.E. Engulfment is required for cell competition. Cell 2007, 129:1215-1225.
    • (2007) Cell , vol.129 , pp. 1215-1225
    • Li, W.1    Baker, N.E.2
  • 42
    • 58149158218 scopus 로고    scopus 로고
    • CD47 on experimentally senescent murine RBCs inhibits phagocytosis following Fcγ receptor-mediated but not scavenger receptor-mediated recognition by macrophages
    • Olsson M., Oldenborg P.A. CD47 on experimentally senescent murine RBCs inhibits phagocytosis following Fcγ receptor-mediated but not scavenger receptor-mediated recognition by macrophages. Blood 2008, 112:4259-4267.
    • (2008) Blood , vol.112 , pp. 4259-4267
    • Olsson, M.1    Oldenborg, P.A.2
  • 43
    • 0034674421 scopus 로고    scopus 로고
    • Role of CD47 as a marker of self on red blood cells
    • Oldenborg P.A., et al. Role of CD47 as a marker of self on red blood cells. Science 2000, 288:2051-2054.
    • (2000) Science , vol.288 , pp. 2051-2054
    • Oldenborg, P.A.1
  • 44
    • 34548120227 scopus 로고    scopus 로고
    • Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation
    • Khandelwal S., et al. Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation. Transfusion 2007, 47:1725-1732.
    • (2007) Transfusion , vol.47 , pp. 1725-1732
    • Khandelwal, S.1
  • 45
    • 0027958313 scopus 로고
    • Bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages
    • Lagasse E., Weissman I.L. Bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages. J. Exp. Med. 1994, 179:1047-1052.
    • (1994) J. Exp. Med. , vol.179 , pp. 1047-1052
    • Lagasse, E.1    Weissman, I.L.2
  • 46
    • 50149091496 scopus 로고    scopus 로고
    • PAI-1 inhibits neutrophil efferocytosis
    • Park Y.J., et al. PAI-1 inhibits neutrophil efferocytosis. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:11784-11789.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 11784-11789
    • Park, Y.J.1
  • 47
    • 67650646082 scopus 로고    scopus 로고
    • CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis
    • Jaiswal S., et al. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell 2009, 138:271-285.
    • (2009) Cell , vol.138 , pp. 271-285
    • Jaiswal, S.1
  • 48
    • 57749122043 scopus 로고    scopus 로고
    • NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A
    • Frasch S.C., et al. NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A. J. Biol. Chem. 2008, 283:33736-33749.
    • (2008) J. Biol. Chem. , vol.283 , pp. 33736-33749
    • Frasch, S.C.1
  • 49
    • 67149098316 scopus 로고    scopus 로고
    • Neutrophils phagocytise activated platelets in vivo: a phosphatidylserine, P-selectin, and β2 integrin-dependent cell clearance program
    • Maugeri N., et al. Neutrophils phagocytise activated platelets in vivo: a phosphatidylserine, P-selectin, and β2 integrin-dependent cell clearance program. Blood 2009, 113:5254-5265.
    • (2009) Blood , vol.113 , pp. 5254-5265
    • Maugeri, N.1
  • 50
    • 0034508217 scopus 로고    scopus 로고
    • The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
    • Lindsten T., et al. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol. Cell 2000, 6:1389-1399.
    • (2000) Mol. Cell , vol.6 , pp. 1389-1399
    • Lindsten, T.1
  • 51
    • 79958292813 scopus 로고    scopus 로고
    • Hemophagocytosis causes a consumptive anemia of inflammation
    • Zoller E.E., et al. Hemophagocytosis causes a consumptive anemia of inflammation. J. Exp. Med. 2011, 208:1203-1214.
    • (2011) J. Exp. Med. , vol.208 , pp. 1203-1214
    • Zoller, E.E.1
  • 52
    • 36248962144 scopus 로고    scopus 로고
    • A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion
    • Overholtzer M., et al. A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion. Cell 2007, 131:966-979.
    • (2007) Cell , vol.131 , pp. 966-979
    • Overholtzer, M.1
  • 53
    • 33645750798 scopus 로고    scopus 로고
    • Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells
    • Lugini L., et al. Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells. Cancer Res. 2006, 66:3629-3638.
    • (2006) Cancer Res. , vol.66 , pp. 3629-3638
    • Lugini, L.1
  • 54
    • 71749094873 scopus 로고    scopus 로고
    • Internalization of NK cells into tumour cells requires ezrin and leads to a programmed cell-in-cell death
    • Wang S., et al. Internalization of NK cells into tumour cells requires ezrin and leads to a programmed cell-in-cell death. Cell Res. 2009, 19:1350-1362.
    • (2009) Cell Res. , vol.19 , pp. 1350-1362
    • Wang, S.1
  • 55
    • 33746394263 scopus 로고    scopus 로고
    • Genotype-dependent priming to self- and xeno-cannibalism in heterozygous and homozygous lymphoblasts from patients with Huntington's disease
    • Mormone E., et al. Genotype-dependent priming to self- and xeno-cannibalism in heterozygous and homozygous lymphoblasts from patients with Huntington's disease. J. Neurochem. 2006, 98:1090-1099.
    • (2006) J. Neurochem. , vol.98 , pp. 1090-1099
    • Mormone, E.1
  • 56
    • 81155154302 scopus 로고    scopus 로고
    • Neuronal death induced by nanomolar amyloid beta is mediated by primary phagocytosis of neurons by microglia
    • Neniskyte U., et al. Neuronal death induced by nanomolar amyloid beta is mediated by primary phagocytosis of neurons by microglia. J. Biol. Chem. 2011, 286:39904-39913.
    • (2011) J. Biol. Chem. , vol.286 , pp. 39904-39913
    • Neniskyte, U.1
  • 57
    • 84863141913 scopus 로고    scopus 로고
    • MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation
    • Fricker M., et al. MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation. J. Neurosci. 2012, 32:2657-2666.
    • (2012) J. Neurosci. , vol.32 , pp. 2657-2666
    • Fricker, M.1
  • 58
    • 78650666213 scopus 로고    scopus 로고
    • Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia
    • McArthur S., et al. Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. J. Immunol. 2010, 185:6317-6328.
    • (2010) J. Immunol. , vol.185 , pp. 6317-6328
    • McArthur, S.1
  • 59
    • 1942447829 scopus 로고    scopus 로고
    • Microglia promote the death of developing Purkinje cells
    • Marin-Teva J.L., et al. Microglia promote the death of developing Purkinje cells. Neuron 2004, 41:535-547.
    • (2004) Neuron , vol.41 , pp. 535-547
    • Marin-Teva, J.L.1
  • 60
    • 51149091666 scopus 로고    scopus 로고
    • Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor
    • Wakselman S., et al. Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor. J. Neurosci. 2008, 28:8138-8143.
    • (2008) J. Neurosci. , vol.28 , pp. 8138-8143
    • Wakselman, S.1
  • 61
    • 80052633284 scopus 로고    scopus 로고
    • Synaptic pruning by microglia is necessary for normal brain development
    • Paolicelli R.C., et al. Synaptic pruning by microglia is necessary for normal brain development. Science 2011, 333:1456-1458.
    • (2011) Science , vol.333 , pp. 1456-1458
    • Paolicelli, R.C.1
  • 62
    • 79952712455 scopus 로고    scopus 로고
    • A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells
    • Kao A.W., et al. A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:4441-4446.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 4441-4446
    • Kao, A.W.1
  • 63
    • 84862334971 scopus 로고    scopus 로고
    • Primary phagocytosis of neurons by inflamed microglia: potential roles in neurodegeneration
    • Neher J.J., et al. Primary phagocytosis of neurons by inflamed microglia: potential roles in neurodegeneration. Front. Pharmacol. 2012, 3:27.
    • (2012) Front. Pharmacol. , vol.3 , pp. 27
    • Neher, J.J.1
  • 64
    • 81855169964 scopus 로고    scopus 로고
    • Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
    • Kang T.W., et al. Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. Nature 2011, 479:547-551.
    • (2011) Nature , vol.479 , pp. 547-551
    • Kang, T.W.1
  • 65
    • 67650632683 scopus 로고    scopus 로고
    • CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells
    • Majeti R., et al. CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell 2009, 138:286-299.
    • (2009) Cell , vol.138 , pp. 286-299
    • Majeti, R.1
  • 66
    • 79951845617 scopus 로고    scopus 로고
    • Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia
    • Chao M.P., et al. Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia. Cancer Res. 2011, 71:1374-1384.
    • (2011) Cancer Res. , vol.71 , pp. 1374-1384
    • Chao, M.P.1
  • 67
    • 84255210700 scopus 로고    scopus 로고
    • Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
    • Galluzzi L., et al. Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ. 2012, 19:107-120.
    • (2012) Cell Death Differ. , vol.19 , pp. 107-120
    • Galluzzi, L.1
  • 68
    • 78649901091 scopus 로고    scopus 로고
    • Alternative cell death mechanisms in development and beyond
    • Yuan J., Kroemer G. Alternative cell death mechanisms in development and beyond. Genes Dev. 2010, 24:2592-2602.
    • (2010) Genes Dev. , vol.24 , pp. 2592-2602
    • Yuan, J.1    Kroemer, G.2
  • 69
    • 33947225091 scopus 로고    scopus 로고
    • Quantification of T-cell dynamics: from telomeres to DNA labeling
    • Borghans J.A., de Boer R.J. Quantification of T-cell dynamics: from telomeres to DNA labeling. Immunol. Rev. 2007, 216:35-47.
    • (2007) Immunol. Rev. , vol.216 , pp. 35-47
    • Borghans, J.A.1    de Boer, R.J.2
  • 70
    • 20944438218 scopus 로고    scopus 로고
    • B-cell kinetics in humans: rapid turnover of peripheral blood memory cells
    • Macallan D.C., et al. B-cell kinetics in humans: rapid turnover of peripheral blood memory cells. Blood 2005, 105:3633-3640.
    • (2005) Blood , vol.105 , pp. 3633-3640
    • Macallan, D.C.1
  • 71
    • 0346363876 scopus 로고    scopus 로고
    • The organization of human epidermis: functional epidermal units and phi proportionality
    • Hoath S.B., Leahy D.G. The organization of human epidermis: functional epidermal units and phi proportionality. J. Invest. Dermatol. 2003, 121:1440-1446.
    • (2003) J. Invest. Dermatol. , vol.121 , pp. 1440-1446
    • Hoath, S.B.1    Leahy, D.G.2
  • 72
    • 62449317819 scopus 로고    scopus 로고
    • Cell death in the skin
    • Lippens S., et al. Cell death in the skin. Apoptosis 2009, 14:549-569.
    • (2009) Apoptosis , vol.14 , pp. 549-569
    • Lippens, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.