ERK1 and ERK2 present functional redundancy in tetrapods despite higher evolution rate of ERK1

BMC Evolutionary Biology

Volumn 15, Issue 1, 2015, Pages

  Buscà, Roser ^a   Christen, Richard ^b,c   Lovern, Matthew ^d   Clifford, Alexander M ^e,f   Yue, Jia Xing ^a   Goss, Greg G ^e,f   Pouysségur, Jacques ^a,g   Lenormand, Philippe ^a  

^a UNIVERSITY OF NICE SOPHIA ANTIPOLIS   (France)

^b Université de Nice Sophia Antipolis ^*  (France)

^c UNIVERSITÉ CÔTE D'AZUR   (France)

^d OKLAHOMA STATE UNIVERSITY   (United States)

^e UNIVERSITY OF ALBERTA   (Canada)

^f BAMFIELD MARINE SCIENCES CENTRE   (Canada)

^g CENTRE SCIENTIFIQUE DE MONACO   (Monaco)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIBODY; BRAIN; CANCER; CLONE; COGNITION; EVOLUTIONARY BIOLOGY; GENE EXPRESSION; MENTAL HEALTH; MOLECULAR ANALYSIS; PHYLOGENETICS; PROTEIN; RODENT; TUMOR;

ANIMALIA; GEKKONIDAE; MUS; MYA; SERPENTES; SQUAMATA; TETRAPODA; VERTEBRATA;

MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMALL INTERFERING RNA;

ANIMAL; CLASSIFICATION; EVOLUTION; GENETICS; METABOLISM; MOLECULAR EVOLUTION; MOUSE; PHOSPHORYLATION; PHYLOGENY; SIGNAL TRANSDUCTION; VERTEBRATE;

ANIMALS; BIOLOGICAL EVOLUTION; EVOLUTION, MOLECULAR; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PHYLOGENY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VERTEBRATES;

EID: 84940666338     PISSN: None     EISSN: 14712148     Source Type: Journal    
DOI: 10.1186/s12862-015-0450-x     Document Type: Article

References (47)

1. Chambard JC, Lefloch R, Pouyssegur J, Lenormand P. ERK implication in cell cycle regulation. Biochim Biophys Acta. 2007;1773(8):1299-310.
2. Tang N, Marshall WF, McMahon M, Metzger RJ, Martin GR. Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape. Science. 2011;333(6040):342-5.
3. Kelleher 3rd RJ, Govindarajan A, Jung HY, Kang H, Tonegawa S. Translational control by MAPK signaling in long-term synaptic plasticity and memory. Cell. 2004;116(3):467-79.
4. Cui Y, Costa RM, Murphy GG, Elgersma Y, Zhu Y, Gutmann DH, et al. Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell. 2008;135(3):549-60.
5. Torii S, Yamamoto T, Tsuchiya Y, Nishida E. ERK MAP kinase in G cell cycle progression and cancer. Cancer Sci. 2006;97(8):697-702.
6. Samuels IS, Karlo JC, Faruzzi AN, Pickering K, Herrup K, Sweatt JD, et al. Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function. J Neurosci. 2008;28(27):6983-95.
7. Boulton TG, Nye SH, Robbins DJ, Ip NY, Radziejewska E, Morgenbesser SD, et al. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell. 1991;65(4):663-75.
8. Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, et al. Mutations of the BRAF gene in human cancer. Nature. 2002;417(6892):949-54.
9. Robbins DJ, Zhen E, Owaki H, Vanderbilt CA, Ebert D, Geppert TD, et al. Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro. J Biol Chem. 1993;268(7):5097-106.
10. Lefloch R, Pouyssegur J, Lenormand P. Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels. Mol Cell Biol. 2008;28(1):511-27.
11. Lenormand P, Sardet C, Pagès G, L'Allemain G, Brunet A, Pouysségur J. Growth Factors Induce Nuclear Translocation of MAP Kinases (p42maPk and p44mapk) but not of Their Activator MAP Kinase Kinase (p45mapkk) in Fibroblasts. J Cell Biol. 1993;122:1079-89.
12. von Kriegsheim A, Baiocchi D, Birtwistle M, Sumpton D, Bienvenut W, Morrice N, et al. Cell fate decisions are specified by the dynamic ERK interactome. Nat Cell Biol. 2009;11(12):1458-64.
13. Lee T, Hoofnagle AN, Kabuyama Y, Stroud J, Min X, Goldsmith EJ, et al. Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry. Mol Cell. 2004;14(1):43-55.
14. Liu S, Sun JP, Zhou B, Zhang ZY. Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3. Proc Natl Acad Sci U S A. 2006;103(14):5326-31.
15. Saba-El-Leil MK, Vella FD, Vernay B, Voisin L, Chen L, Labrecque N, et al. An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development. EMBO Rep. 2003;4(10):964-8.
16. Yao Y, Li W, Wu J, Germann UA, Su MS, Kuida K, et al. Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation. Proc Natl Acad Sci U S A. 2003;100(22):12759-64.
17. Hatano N, Mori Y, Oh-hora M, Kosugi A, Fujikawa T, Nakai N, et al. Essential role for ERK2 mitogen-activated protein kinase in placental development. Genes Cells. 2003;8(11):847-56.
18. Pages G, Guerin S, Grall D, Bonino F, Smith A, Anjuere F, et al. Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science. 1999;286(5443):1374-7.
19. Zeng P, Wagoner HA, Pescovitz OH, Steinmetz R. RNA interference (RNAi) for extracellular signal-regulated kinase 1 (ERK1) alone is sufficient to suppress cell viability in ovarian cancer cells. Cancer Biol Ther. 2005;4(9):961-7.
20. Fremin C, Ezan F, Boisselier P, Bessard A, Pages G, Pouyssegur J, et al. ERK2 but not ERK1 plays a key role in hepatocyte replication: an RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes. Hepatology. 2007;45(4):1035-45.
21. Shin S, Dimitri CA, Yoon SO, Dowdle W, Blenis J. ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling events. Mol Cell. 2010;38(1):114-27.
22. Fan HY, Liu Z, Shimada M, Sterneck E, Johnson PF, Hedrick SM, et al. MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility. Science. 2009;324(5929):938-41.
23. Voisin L, Saba-El-Leil MK, Julien C, Fremin C, Meloche S. Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation. Mol Cell Biol. 2010;30(12):2918-32.
24. Smith JJ, Kuraku S, Holt C, Sauka-Spengler T, Jiang N, Campbell MS, et al. Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution. Nat Genet. 2013;45(4):415-21. 421e411-412.
25. Venkatesh B, Lee AP, Ravi V, Maurya AK, Lian MM, Swann JB, et al. Elephant shark genome provides unique insights into gnathostome evolution. Nature. 2014;505(7482):174-9.
26. Near TJ, Eytan RI, Dornburg A, Kuhn KL, Moore JA, Davis MP, et al. Resolution of ray-finned fish phylogeny and timing of diversification. Proc Natl Acad Sci U S A. 2012;109(34):13698-703.
27. Lefloch R, Pouyssegur J, Lenormand P. Total ERK1/2 activity regulates cell proliferation. Cell Cycle. 2009;8(5):705-11.
28. Alfoldi J, Di Palma F, Grabherr M, Williams C, Kong L, Mauceli E, et al. The genome of the green anole lizard and a comparative analysis with birds and mammals. Nature. 2011;477(7366):587-91.
29. Li M, Liu J, Zhang C. Evolutionary history of the vertebrate mitogen activated protein kinases family. PLoS One. 2011;6(10):e26999.
30. Putnam NH, Butts T, Ferrier DE, Furlong RF, Hellsten U, Kawashima T, et al. The amphioxus genome and the evolution of the chordate karyotype. Nature. 2008;453(7198):1064-71.
31. Aury JM, Jaillon O, Duret L, Noel B, Jubin C, Porcel BM, et al. Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia. Nature. 2006;444(7116):171-8.
32. Blasco RB, Francoz S, Santamaria D, Canamero M, Dubus P, Charron J, et al. c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma. Cancer Cell. 2011;19(5):652-63.
33. Frémin C, Saba-El-Leil MK, Lévesque K, Ang S-L, Meloche S. Functional Redundancy of ERK1 and ERK2 MAP Kinases During Development. Cell Reports. 2015;12:913-21.
34. Choi SS, Hannenhalli S. Three independent determinants of protein evolutionary rate. J Mol Evol. 2013;76(3):98-111.
35. Pal C, Papp B, Hurst LD. Highly expressed genes in yeast evolve slowly. Genetics. 2001;158(2):927-31.
36. Liao BY, Scott NM, Zhang J. Impacts of gene essentiality, expression pattern, and gene compactness on the evolutionary rate of mammalian proteins. Mol Biol Evol. 2006;23(11):2072-80.
37. Marais G, Nouvellet P, Keightley PD, Charlesworth B. Intron size and exon evolution in Drosophila. Genetics. 2005;170(1):481-5.
38. Polazzi E, Alibardi L. Cell culture from lizard skin: a tool for the study of epidermal differentiation. Tissue Cell. 2011;43(6):350-8.
39. Darriba D, Taboada GL, Doallo R, Posada D. ProtTest 3: fast selection of best-fit models of protein evolution. Bioinformatics. 2011;27(8):1164-5.
40. Gouy M, Guindon S, Gascuel O. SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building. Mol Biol Evol. 2010;27(2):221-4.
41. Stern A, Doron-Faigenboim A, Erez E, Martz E, Bacharach E, Pupko T. Selecton 2007: advanced models for detecting positive and purifying selection using a Bayesian inference approach. Nucleic Acids Res. 2007;35(Web Server issue):W506-11.
42. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S. MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol. 2013;30(12):2725-9.
43. Jukes TH, Cantor CR. Evolution of protein molecules. New York: Academic; 1969.
44. Zuckerkandl E, Pauling L. Evolutionary divergence and convergence in proteins. New York: Academic; 1965.
45. Nei M, Gojobori T. Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Mol Biol Evol. 1986;3(5):418-26.
46. Zhang F, Strand A, Robbins D, Cobb MH, Goldsmith EJ. Atomic structure of the MAP kinase ERK2 at 2.3 A resolution. Nature. 1994;367:704-11.
47. Chaikuad A, Tacconi EM, Zimmer J, Liang Y, Gray NS, Tarsounas M, et al. A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics. Nat Chem Biol. 2014;10(10):853-60.