Nanoparticles made from xyloglucan-block-polycaprolactone copolymers: Safety assessment for drug delivery

Toxicological Sciences

Volumn 147, Issue 1, 2015, Pages 104-115

  Mazzarino, Letícia ^a   Loch Neckel, Gecioni ^a   Bubniak, Lorena dos Santos ^a   Ourique, Fabiana ^a   Otsuka, Issei ^b   Halila, Sami ^b   Pedrosa, Rozangela Curi ^a   Santos Silva, Maria Cláudia ^a   Lemos Senna, Elenara ^a   Muniz, Edvani Curti ^c   Borsali, Redouane ^b  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIV GRENOBLE ALPES   (France)

^c STATE UNIVERSITY OF MARINGÁ   (Brazil)

Author keywords

Cytotoxicity; Genotoxicity; Hemolysis; In vivo toxicity; Nanoparticle; Nanotoxicology

Indexed keywords

COPOLYMER; DNA; GLUCAN; NANOPARTICLE; POLYCAPROLACTONE; UNCLASSIFIED DRUG; XYLOGLUCAN; MUTAGENIC AGENT; POLYESTER; POLYMER; XYLAN;

ACUTE TOXICITY; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BLOOD COMPATIBILITY; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG DELIVERY SYSTEM; ERYTHROCYTE; FEMALE; FETUS LUNG; GENOTOXICITY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG FIBROBLAST; MORPHOLOGY; MORTALITY; MOUSE; NONHUMAN; PARTICLE SIZE; RISK ASSESSMENT; WEIGHT REDUCTION; ZETA POTENTIAL; ADVERSE EFFECTS; ANIMAL; BAGG ALBINO MOUSE; BLOOD CELL COUNT; BODY WEIGHT; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; HEMOLYSIS;

ANIMALS; APOPTOSIS; BLOOD CELL COUNT; BODY WEIGHT; CELL LINE; CELL SURVIVAL; DNA DAMAGE; DRUG DELIVERY SYSTEMS; ERYTHROCYTES; FEMALE; GLUCANS; HEMOLYSIS; HUMANS; MICE; MICE, INBRED BALB C; MUTAGENS; NANOPARTICLES; POLYESTERS; POLYMERS; XYLANS;

EID: 84940639332     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfv114     Document Type: Article

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