The increases in relative mRNA expressions of inflammatory cytokines and chemokines in splenic macrophages from rats exposed to multi-walled carbon nanotubes by whole-body inhalation for 13 weeks

Inhalation Toxicology

Volumn 26, Issue 12, 2014, Pages 750-758

  Kido, Takamasa ^a,b   Tsunoda, Masashi ^b   Kasai, Tatsuya ^c   Sasaki, Toshiaki ^c   Umeda, Yumi ^c   Senoh, Hideki ^c   Yanagisawa, Hiroyuki ^a   Asakura, Masumi ^c   Aizawa, Yoshiharu ^d   Fukushima, Shoji ^c  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c JAPAN INDUSTRIAL SAFETY AND HEALTH ASSOCIATION   (Japan)

^d KITASATO UNIVERSITY   (Japan)

Author keywords

Cytokines; Immunotoxicology; Multi walled carbon nanotube; Occupational health; Rat

Indexed keywords

CHEMOKINE; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MULTI WALLED NANOTUBE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; AEROSOL; CARBON NANOTUBE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CELL POPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXPOSURE; FEMALE; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOTOXICITY; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SPLEEN CELL; SPLEEN WEIGHT; T LYMPHOCYTE; TOXIC INHALATION; ADVERSE EFFECTS; AEROSOL; AGONISTS; ALGORITHM; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMICALLY INDUCED; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECTS; FISCHER 344 RAT; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; PATHOLOGY; SPLEEN; TISSUE DISTRIBUTION; TOXICITY TESTING; UPREGULATION;

RATTUS;

AEROSOLS; ALGORITHMS; ANIMALS; CELLS, CULTURED; CHEMOKINES; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FEMALE; INFLAMMATION; INHALATION EXPOSURE; MACROPHAGES; MALE; NANOTUBES, CARBON; RATS, INBRED F344; RNA, MESSENGER; SPLEEN; T-LYMPHOCYTES; TISSUE DISTRIBUTION; TOXICITY TESTS, SUBCHRONIC; UP-REGULATION;

EID: 84925066487     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2014.953275     Document Type: Article

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