메뉴 건너뛰기




Volumn 47, Issue 9, 2015, Pages 1003-1010

Genomic spectra of biliary tract cancer

Author keywords

[No Author keywords available]

Indexed keywords

AKT3 PROTEIN; APC PROTEIN; AT RICH INTERACTIVE DOMAIN 2; ATM PROTEIN; BAP1 PROTEIN; CYCLIN D1; CYCLIN D3; CYCLIN DEPENDENT KINASE INHIBITOR 2A; ELF3 PROTEIN; EPHRIN RECEPTOR A2; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; HISTONE DEMETHYLASE; HYDROLASE; ISOCITRATE DEHYDROGENASE 1; LYSINE K SPECIFIC DEMETHYLASE 5D; MITOGEN ACTIVATED PROTEIN KINASE; POLYBROMO 1 PROTEIN; PRKACA PROTEIN; PRKACB PROTEIN; PROTEIN; PROTEIN MDM2; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RETINOBLASTOMA BINDING PROTEIN 2; UNCLASSIFIED DRUG; UTY PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT; DNA BINDING PROTEIN; ELF3 PROTEIN, HUMAN; FGFR1 PROTEIN, HUMAN; FGFR2 PROTEIN, HUMAN; ONCOPROTEIN; PRKACA PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS;

EID: 84940556535     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3375     Document Type: Article
Times cited : (969)

References (42)
  • 1
    • 79952232216 scopus 로고    scopus 로고
    • Global cancer statistics
    • Jemal, A. et al. Global cancer statistics. CA Cancer J. Clin. 61, 69-90 (2011).
    • (2011) CA Cancer J. Clin. , vol.61 , pp. 69-90
    • Jemal, A.1
  • 2
    • 3042789089 scopus 로고    scopus 로고
    • Worldwide trends in mortality from biliary tract malignancies
    • Patel, T. Worldwide trends in mortality from biliary tract malignancies. BMC Cancer 2, 10 (2002).
    • (2002) BMC Cancer , vol.2 , pp. 10
    • Patel, T.1
  • 3
    • 79959572626 scopus 로고    scopus 로고
    • Risk factors for cholangiocarcinoma
    • Tyson, G.L. & El-Serag, H.B. Risk factors for cholangiocarcinoma. Hepatology 54, 173-184 (2011).
    • (2011) Hepatology , vol.54 , pp. 173-184
    • Tyson, G.L.1    El-Serag, H.B.2
  • 4
    • 85193457759 scopus 로고    scopus 로고
    • Diagnosis, and management of cholangiocarcinoma
    • Rizvi, S. & Gores, G.J. Pathogenesis, diagnosis, and management of cholangiocarcinoma. Gastroenterology 145, 1215-1229 (2013).
    • (2013) Gastroenterology , vol.145 , pp. 1215-1229
    • Rizvi, S.1    Pathogenesis, J.G.G.2
  • 5
    • 84902786936 scopus 로고    scopus 로고
    • Cholangiocarcinoma
    • Razumilava, N. & Gores, G.J. Cholangiocarcinoma. Lancet 383, 2168-2179 (2014).
    • (2014) Lancet , vol.383 , pp. 2168-2179
    • Razumilava, N.1    Gores, G.J.2
  • 7
    • 84882837534 scopus 로고    scopus 로고
    • Signatures of mutational processes in human cancer
    • Alexandrov, L.B. et al. Signatures of mutational processes in human cancer. Nature 500, 415-421 (2013).
    • (2013) Nature , vol.500 , pp. 415-421
    • Alexandrov, L.B.1
  • 8
    • 84888385562 scopus 로고    scopus 로고
    • Exome sequencing identifes distinct mutational patterns in liver fuke-related and non-infection-related bile duct cancers
    • Chan-On, W. et al. Exome sequencing identifes distinct mutational patterns in liver fuke-related and non-infection-related bile duct cancers. Nat. Genet. 45, 1474-1478 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 1474-1478
    • Chan-On, W.1
  • 9
    • 84905721813 scopus 로고    scopus 로고
    • Whole-exome and targeted gene sequencing of gallbladder carcinoma identifes recurrent mutations in the ErbB pathway
    • Li, M. et al. Whole-exome and targeted gene sequencing of gallbladder carcinoma identifes recurrent mutations in the ErbB pathway. Nat. Genet. 46, 872-876 (2014).
    • (2014) Nat. Genet. , vol.46 , pp. 872-876
    • Li, M.1
  • 10
    • 84878781242 scopus 로고    scopus 로고
    • Identifcation of targetable FGFR gene fusions in diverse cancers
    • Wu, Y.M. et al. Identifcation of targetable FGFR gene fusions in diverse cancers. Cancer Discov. 3, 636-647 (2013).
    • (2013) Cancer Discov. , vol.3 , pp. 636-647
    • Wu, Y.M.1
  • 11
    • 84896492774 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 tyrosine kinase fusions defne a unique molecular subtype of cholangiocarcinoma
    • Arai, Y. et al. Fibroblast growth factor receptor 2 tyrosine kinase fusions defne a unique molecular subtype of cholangiocarcinoma. Hepatology 59, 1427-1434 (2014).
    • (2014) Hepatology , vol.59 , pp. 1427-1434
    • Arai, Y.1
  • 12
    • 84896732099 scopus 로고    scopus 로고
    • Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fbrolamellar hepatocellular carcinoma
    • Honeyman, J.N. et al. Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fbrolamellar hepatocellular carcinoma. Science 343, 1010-1014 (2014).
    • (2014) Science , vol.343 , pp. 1010-1014
    • Honeyman, J.N.1
  • 13
    • 84865459654 scopus 로고    scopus 로고
    • Recurrent R-spondin fusions in colon cancer
    • Seshagiri, S. et al. Recurrent R-spondin fusions in colon cancer. Nature 488, 660-664 (2012).
    • (2012) Nature , vol.488 , pp. 660-664
    • Seshagiri, S.1
  • 14
    • 0033523268 scopus 로고    scopus 로고
    • Cancer risks in BRCA2 mutation carriers
    • Breast Cancer Linkage Consortium. Cancer risks in BRCA2 mutation carriers. J. Natl. Cancer Inst. 91, 1310-1316 (1999).
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 1310-1316
  • 15
    • 84890127613 scopus 로고    scopus 로고
    • Expanding the clinical phenotype of hereditary BAP1 cancer predisposition syndrome, reporting three new cases
    • Pilarski, R. et al. Expanding the clinical phenotype of hereditary BAP1 cancer predisposition syndrome, reporting three new cases. Genes Chromosom. Cancer 53, 177-182 (2014).
    • (2014) Genes Chromosom. Cancer , vol.53 , pp. 177-182
    • Pilarski, R.1
  • 16
    • 84907033777 scopus 로고    scopus 로고
    • Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
    • Saha, S.K. et al. Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer. Nature 513, 110-114 (2014).
    • (2014) Nature , vol.513 , pp. 110-114
    • Saha, S.K.1
  • 17
    • 84922551107 scopus 로고    scopus 로고
    • Trans-ancestry mutational landscape of hepatocellular carcinoma genomes
    • Totoki, Y. et al. Trans-ancestry mutational landscape of hepatocellular carcinoma genomes. Nat. Genet. 46, 1267-1273 (2014).
    • (2014) Nat. Genet. , vol.46 , pp. 1267-1273
    • Totoki, Y.1
  • 18
    • 84894231823 scopus 로고    scopus 로고
    • Landscape of genomic alterations in cervical carcinomas
    • Ojesina, A.I. et al. Landscape of genomic alterations in cervical carcinomas. Nature 506, 371-375 (2014).
    • (2014) Nature , vol.506 , pp. 371-375
    • Ojesina, A.I.1
  • 19
    • 0037067653 scopus 로고    scopus 로고
    • E2F4/5 and p107 as Smad cofactors linking the TGFβ receptor to c-myc repression
    • Chen, C.R., Kang, Y., Siegel, P.M. & Massagué, J. E2F4/5 and p107 as Smad cofactors linking the TGFβ receptor to c-myc repression. Cell 110, 19-32 (2002).
    • (2002) Cell , vol.110 , pp. 19-32
    • Chen, C.R.1    Kang, Y.2    Siegel, P.M.3    Massagué, J.4
  • 20
    • 84890717859 scopus 로고    scopus 로고
    • Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
    • Shi, J. et al. Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes Dev. 27, 2648-2662 (2013).
    • (2013) Genes Dev. , vol.27 , pp. 2648-2662
    • Shi, J.1
  • 21
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll, D.M. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 12, 252-264 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 22
    • 84920956732 scopus 로고    scopus 로고
    • PD-1 blockade induces responses by inhibiting adaptive immune resistance
    • Tumeh, P.C. et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature 515, 568-571 (2014).
    • (2014) Nature , vol.515 , pp. 568-571
    • Tumeh, P.C.1
  • 23
    • 84883356320 scopus 로고    scopus 로고
    • Evidence for APOBEC3B mutagenesis in multiple human cancers
    • Burns, M.B., Temiz, N.A. & Harris, R.S. Evidence for APOBEC3B mutagenesis in multiple human cancers. Nat. Genet. 45, 977-983 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 977-983
    • Burns, M.B.1    Temiz, N.A.2    Harris, R.S.3
  • 24
    • 84896745936 scopus 로고    scopus 로고
    • Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome
    • Beuschlein, F. et al. Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome. N. Engl. J. Med. 370, 1019-1028 (2014).
    • (2014) N. Engl. J. Med. , vol.370 , pp. 1019-1028
    • Beuschlein, F.1
  • 25
    • 0033812849 scopus 로고    scopus 로고
    • Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with the Carney complex
    • Kirschner, L.S. et al. Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with the Carney complex. Nat. Genet. 26, 89-92 (2000).
    • (2000) Nat. Genet. , vol.26 , pp. 89-92
    • Kirschner, L.S.1
  • 26
    • 84920989984 scopus 로고    scopus 로고
    • Long-term culture of genome-stable bipotent stem cells from adult human liver
    • Huch, M. et al. Long-term culture of genome-stable bipotent stem cells from adult human liver. Cell 160, 299-312 (2015).
    • (2015) Cell , vol.160 , pp. 299-312
    • Huch, M.1
  • 27
    • 30144443269 scopus 로고    scopus 로고
    • Paradoxical roles of the immune system during cancer development
    • de Visser, K.E., Eichten, A. & Coussens, L.M. Paradoxical roles of the immune system during cancer development. Nat. Rev. Cancer 6, 24-37 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 24-37
    • De Visser, K.E.1    Eichten, A.2    Coussens, L.M.3
  • 28
    • 84918828514 scopus 로고    scopus 로고
    • Genetic basis for clinical response to CTLA-4 blockade in melanoma
    • Snyder, A. et al. Genetic basis for clinical response to CTLA-4 blockade in melanoma. N. Engl. J. Med. 371, 2189-2199 (2014).
    • (2014) N. Engl. J. Med. , vol.371 , pp. 2189-2199
    • Snyder, A.1
  • 29
    • 84928761118 scopus 로고    scopus 로고
    • Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
    • Rizvi, N.A. et al. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science 348, 124-128 (2015).
    • (2015) Science , vol.348 , pp. 124-128
    • Rizvi, N.A.1
  • 30
    • 84858760109 scopus 로고    scopus 로고
    • Combining immunotherapy and targeted therapies in cancer treatment
    • Vanneman, M. & Dranoff, G. Combining immunotherapy and targeted therapies in cancer treatment. Nat. Rev. Cancer 12, 237-251 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 237-251
    • Vanneman, M.1    Dranoff, G.2
  • 31
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li, H. & Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-1760 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 32
    • 68549104404 scopus 로고    scopus 로고
    • The Sequence Alignment/Map format and SAMtools
    • Li, H. et al. The Sequence Alignment/Map format and SAMtools. Bioinformatics 25, 2078-2079 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 2078-2079
    • Li, H.1
  • 33
    • 79955166265 scopus 로고    scopus 로고
    • GISTIC2.0 facilitates sensitive and confdent localization of the targets of focal somatic copy-number alteration in human cancers
    • Mermel, C.H. et al. GISTIC2.0 facilitates sensitive and confdent localization of the targets of focal somatic copy-number alteration in human cancers. Genome Biol. 12, R41 (2011).
    • (2011) Genome Biol. , vol.12 , pp. R41
    • Mermel, C.H.1
  • 34
    • 3543105225 scopus 로고    scopus 로고
    • Circular binary segmentation for the analysis of array-based DNA copy number data
    • Olshen, A.B., Venkatraman, E.S., Lucito, R. & Wigler, M. Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics 5, 557-572 (2004).
    • (2004) Biostatistics , vol.5 , pp. 557-572
    • Olshen, A.B.1    Venkatraman, E.S.2    Lucito, R.3    Wigler, M.4
  • 35
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-effcient alignment of short DNA sequences to the human genome
    • Langmead, B., Trapnell, C., Pop, M. & Salzberg, S.L. Ultrafast and memory-effcient alignment of short DNA sequences to the human genome. Genome Biol. 10, R25 (2009).
    • (2009) Genome Biol. , vol.10 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 36
    • 84880507665 scopus 로고    scopus 로고
    • Mutational heterogeneity in cancer and the search for new cancer-associated genes
    • Lawrence, M.S. et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature 499, 214-218 (2013).
    • (2013) Nature , vol.499 , pp. 214-218
    • Lawrence, M.S.1
  • 37
    • 84873186179 scopus 로고    scopus 로고
    • Deciphering signatures of mutational processes operative in human cancer
    • Alexandrov, L.B. et al. Deciphering signatures of mutational processes operative in human cancer. Cell Rep. 3, 246-259 (2013).
    • (2013) Cell Rep. , vol.3 , pp. 246-259
    • Alexandrov, L.B.1
  • 38
    • 1642529511 scopus 로고    scopus 로고
    • Metagenes and molecular pattern discovery using matrix factorization
    • Brunet, J.P. et al. Metagenes and molecular pattern discovery using matrix factorization. Proc. Natl. Acad. Sci. USA 101, 4164-4169 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4164-4169
    • Brunet, J.P.1
  • 39
    • 84938600057 scopus 로고    scopus 로고
    • Systematic identifcation of cancer driving signaling pathways based on mutual exclusivity of genomic alterations
    • Babur, Ö. et al. Systematic identifcation of cancer driving signaling pathways based on mutual exclusivity of genomic alterations. Genome Biol. 16, 45 (2015).
    • (2015) Genome Biol. , vol.16 , pp. 45
    • Babur, Ö.1
  • 40
    • 84878498657 scopus 로고    scopus 로고
    • Simultaneous identifcation of multiple driver pathways in cancer
    • Leiserson, M.D., Blokh, D., Sharan, R. & Raphael, B.J. Simultaneous identifcation of multiple driver pathways in cancer. PLOS Comput. Biol. 9, e1003054 (2013).
    • (2013) PLOS Comput. Biol. , vol.9 , pp. e1003054
    • Leiserson, M.D.1    Blokh, D.2    Sharan, R.3    Raphael, B.J.4
  • 41
    • 84875016233 scopus 로고    scopus 로고
    • Pattern discovery and cancer gene identifcation in integrated cancer genomic data
    • Mo, Q. et al. Pattern discovery and cancer gene identifcation in integrated cancer genomic data. Proc. Natl. Acad. Sci. USA 110, 4245-4250 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 4245-4250
    • Mo, Q.1
  • 42
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profles
    • Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profles. Proc. Natl. Acad. Sci. USA 102, 15545-15550 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.