Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma

Science

Volumn 343, Issue 6174, 2014, Pages 1010-1014

  Honeyman, Joshua N ^a,b   Simon, Elana P ^a,c   Robine, Nicolas ^d   Chiaroni Clarke, Rachel ^a   Darcy, David G ^a,b   Lim, Irene Isabel P ^a,b   Gleason, Caroline E ^a   Murphy, Jennifer M ^a,b   Rosenberg, Brad R ^a   Teegan, Lydia ^a   Takacs, Constantin N ^a   Botero, Sergio ^a   Belote, Rachel ^a   Germer, Soren ^d   Emde, Anne Katrin ^d   Vacic, Vladimir ^d   Bhanot, Umesh ^b   LaQuaglia, Michael P ^b   Simon, Sanford M ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c Dalton School   (United States)

^d NEW YORK GENOME CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELL ORGANELLE; CHEATING BEHAVIOR; DETECTION METHOD; DISEASE PREVALENCE; DNA; PATHOGENICITY; PROTEIN; RNA;

ARTICLE; CHROMOSOME 19; COMPLEX FORMATION; DNAJB1 GENE; FIBROLAMELLAR HEPATOCELLULAR CARCINOMA; GENE; HUMAN; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PRKACA GENE; CHEMISTRY; CHROMOSOME DELETION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; LIVER TUMOR; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; TUMOR CELL CULTURE;

CYCLIC AMP DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT; DNAJB1 PROTEIN, HUMAN; HEAT SHOCK PROTEIN 40; ONCOPROTEIN; PRKACA PROTEIN, HUMAN;

CARCINOMA, HEPATOCELLULAR; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 19; CYCLIC AMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNITS; GENE EXPRESSION REGULATION, NEOPLASTIC; HSP40 HEAT-SHOCK PROTEINS; HUMANS; LIVER NEOPLASMS; ONCOGENE PROTEINS, FUSION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 84896732099     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1249484     Document Type: Article

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