Bioconversion of FR901459, a novel derivative of cyclosporin A, by Lentzea sp. 7887

Journal of Antibiotics

Volumn 68, Issue 8, 2015, Pages 511-520

  Sasamura, Satoshi ^a,b   Kobayashi, Motoo ^a   Muramatsu, Hideyuki ^a   Yoshimura, Seiji ^a   Kinoshita, Takayoshi ^a,c   Ohki, Hidenori ^a,d   Okada, Kazuki ^a   Deai, Yoko ^a   Yamagishi, Yukiko ^a   Hashimoto, Michizane ^a,b  

^a ASTELLAS PHARMA INC   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

^c Osaka City University   (Japan)

^d National Cerebral and Cardiovascular Center 30602   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 [2 BUTENYL] 4 METHYL LEVO THREONINE; CYCLOSPORIN A DERIVATIVE; DNA 16S; FR 901459; METHYL; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; BACTERIAL DNA; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; RIBOSOME DNA; RNA 16S;

ACTINOBACTERIA; ANALYTIC METHOD; ARTICLE; BIOTRANSFORMATION; CHEMICAL ANALYSIS; CHEMICAL MODIFICATION; CLINICAL EFFECTIVENESS; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENCY; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; HEPATITIS C; HEPATITIS C VIRUS; HYDROXYLATION; LENTZEA; NONHUMAN; PHYLOGENY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TAXONOMIC RANK; BACTERIUM IDENTIFICATION; CHEMICAL STRUCTURE; CHEMISTRY; CLUSTER ANALYSIS; DNA SEQUENCE; DRUG EFFECTS; GENETICS; HEPACIVIRUS; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACTINOBACTERIA; ANTIVIRAL AGENTS; BACTERIAL TYPING TECHNIQUES; BIOTRANSFORMATION; CLUSTER ANALYSIS; CYCLOSPORINE; DNA, BACTERIAL; DNA, RIBOSOMAL; HEPACIVIRUS; IMMUNOSUPPRESSIVE AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PHYLOGENY; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA;

EID: 84940544063     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2015.19     Document Type: Article

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