Strain selection and scale-up fermentation for FR901379 acylase production by Streptomyces sp. no. 6907

Journal of Bioscience and Bioengineering

Volumn 112, Issue 4, 2011, Pages 409-414

  Ueda, Satoshi ^a   Kinoshita, Masayoshi ^a   Tanaka, Fumihiro ^a   Tsuboi, Masaru ^a   Shimizu, Shiho ^a   Oohata, Nobutaka ^a   Hino, Motohiro ^a   Yamada, Masato ^b   Isogai, Yasuhiro ^b   Hashimoto, Seiji ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b TOYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Bioconversion; FR901379 acylase; Medium improvement; Scale up; Strain breeding

Indexed keywords

AGITATION SPEED; DISCHARGE FLOW; FERMENTATION PROCESS; FLANKING REGIONS; FR901379 ACYLASE; FUNGAL INFECTION; GROWTH CONDITIONS; GROWTH MEDIUM; LARGE-SCALE PRODUCTION; LIPOPEPTIDES; MEDIUM IMPROVEMENT; PROTEOLYTIC ACTIVITIES; SCALE-UP; SCREENING METHODS; SKIM MILKS; STRAIN SELECTION; STREPTOMYCES SP; STRUCTURAL GENE; UV IRRADIATION;

CHEMICAL MODIFICATION; CLONING; FERMENTATION; FLUORINE; GENE EXPRESSION; OPTIMIZATION;

BACTERIA;

AMIDASE; FR 901379; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; ENZYME ACTIVITY; ENZYME SYNTHESIS; FERMENTATION; MILK; NONHUMAN; PHENOTYPE; PROTEIN DEGRADATION; RADIATION MUTAGENESIS; STREPTOMYCES; ULTRAVIOLET RADIATION;

AMIDOHYDROLASES; ANTIFUNGAL AGENTS; CULTURE MEDIA; ECHINOCANDINS; FERMENTATION; LIPOPEPTIDES; PEPTIDES, CYCLIC; STREPTOMYCES;

COLEOPHOMA EMPETRI; STREPTOMYCES SP.;

EID: 80054045605     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2011.06.002     Document Type: Article

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