An engineered Escherichia coli having a high intracellular level of ATP and enhanced recombinant protein production

Applied Microbiology and Biotechnology

Volumn 94, Issue 4, 2012, Pages 1079-1086

  Kim, Hye Jung ^a   Kwon, Yeong Deok ^a,c   Lee, Sang Yup ^b   Kim, Pil ^a  

^a The Catholic University of Korea   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c Paik Kwang Industrial Co   (South Korea)

Author keywords

Cellular energy; High intracellular ATP concentration; Recombinant protein expression

Indexed keywords

ALKALINE PROTEASE; BATCH FERMENTATION; CELLULAR ENERGY; CHEMOSTAT CULTURE; CONTROL STRAIN; E. COLI; ENHANCED GREEN FLUORESCENCE PROTEINS; GROWTH PHASE; INTRACELLULAR ATP; INTRACELLULAR LEVELS; PHOSPHOENOLPYRUVATE CARBOXYKINASE; RECOMBINANT PROTEIN EXPRESSION; RECOMBINANT PROTEIN PRODUCTIONS; SOLUBLE PROTEINS;

BIOMASS; CELL CULTURE; ESCHERICHIA COLI; RECOMBINANT PROTEINS;

BIOSYNTHESIS;

ADENOSINE TRIPHOSPHATE; ALKALINE PROTEINASE; GREEN FLUORESCENT PROTEIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); RECOMBINANT PROTEIN;

BIOMASS; BIOTECHNOLOGY; CELL ORGANELLE; COLIFORM BACTERIUM; CONCENTRATION (COMPOSITION); ENGINEERING; ENZYME ACTIVITY; FERMENTATION; GENE EXPRESSION; PROTEIN; RECOMBINATION;

BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM CULTURE; BATCH FERMENTATION; BIOMASS; CHEMOSTAT; CONCENTRATION (PARAMETERS); ESCHERICHIA COLI; GENE OVEREXPRESSION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVIEW; STEADY STATE;

ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEINS; CYTOPLASM; ENDOPEPTIDASES; ESCHERICHIA COLI; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; METABOLIC ENGINEERING; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PODOVIRIDAE; RECOMBINANT PROTEINS;

ESCHERICHIA COLI;

EID: 84862860855     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3779-0     Document Type: Review

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