Biphasic decline of β-cell function with age in euglycemic nonobese diabetic mice parallels diabetes onset

IUBMB Life

Volumn 67, Issue 8, 2015, Pages 634-644

  Cechin, Sirlene R ^a   Lopez Ocejo, Omar ^a   Karpinsky Semper, Darla ^a   Buchwald, Peter ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

beta cell proliferation; glucose tolerance test; insulin secretion; Ki67; NOD; pancreatic islet

Indexed keywords

GLUCOSE; INSULIN; GLUCOSE BLOOD LEVEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HYPERGLYCEMIA; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE IMAGING; INSULIN RELEASE; INSULIN RESPONSE; LONGITUDINAL STUDY; MOLECULAR IMAGING; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; AGING; ANIMAL; DISEASE MODEL; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE TOLERANCE TEST; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; SECRETION (PROCESS);

ANIMALIA; MUS;

AGING; ANIMALS; BLOOD GLUCOSE; CELL PROLIFERATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, INBRED NOD;

EID: 84940462689     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1391     Document Type: Article

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