Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome

Nature Neuroscience

Volumn 18, Issue 9, 2015, Pages 1291-1298

  Witton, Jonathan ^a   Padmashri, Ragunathan ^b,j   Zinyuk, Larissa E ^a   Popov, Victor I ^c,d   Kraev, Igor ^d,e   Line, Samantha J ^f   Jensen, Thomas P ^b   Tedoldi, Angelo ^g   Cummings, Damian M ^g   Tybulewicz, Victor L J ^h,i   Fisher, Elizabeth M C ^b   Bannerman, David M ^f   Randall, Andrew D ^a   Brown, Jonathan T ^a   Edwards, Frances A ^g   Rusakov, Dmitri A ^b,e   Stewart, Michael G ^d   Jones, Matt W ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c INSTITUTE OF CELL BIOPHYSICS   (Russian Federation)

^d OPEN UNIVERSITY   (United Kingdom)

^e LOBACHEVSKY STATE UNIVERSITY OF NIZHNY NOVGOROD   (Russian Federation)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g UNIVERSITY COLLEGE LONDON   (United Kingdom)

^h THE FRANCIS CRICK INSTITUTE   (United Kingdom)

ⁱ IMPERIAL COLLEGE LONDON   (United Kingdom)

^j UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANEUPLOIDY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN SIZE; BRAIN SYNAPTOSOME; CELL DENSITY; CELL STRUCTURE; CHROMOSOME 21; COGNITIVE DEFECT; CONNECTOME; CONTROLLED STUDY; DENTATE GYRUS; DOWN SYNDROME; ELECTRIC POTENTIAL; ENTORHINAL CORTEX; FACILITATION; FEMALE; FIRING RATE; FUNCTIONAL NEUROIMAGING; GENE EXPRESSION; GENE OVEREXPRESSION; GENOTYPE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; HIPPOCAMPAL MOSSY FIBER; IN VITRO STUDY; IN VIVO STUDY; LONG TERM POTENTIATION; MALE; MOSAICISM; MOUSE; NERVE CELL EXCITABILITY; NERVE CELL PLASTICITY; NERVE STIMULATION; NONHUMAN; PHENOTYPE; POSTSYNAPTIC DENSITY; PRESYNAPTIC POTENTIAL; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; TASK PERFORMANCE; WORKING MEMORY; 129 MOUSE; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENETICS; HUMAN; MAZE TEST; NERVE CELL NETWORK; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TRISOMY;

ANIMALS; CA3 REGION, HIPPOCAMPAL; CHROMOSOMES, HUMAN, PAIR 21; DENTATE GYRUS; DISEASE MODELS, ANIMAL; DOWN SYNDROME; HUMANS; MALE; MAZE LEARNING; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; NERVE NET; ORGAN CULTURE TECHNIQUES; TRISOMY;

EID: 84940460671     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.4072     Document Type: Article

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