MRI volumes of the hippocampus and amygdala in adults with Down's syndrome with and without dementia

American Journal of Psychiatry

Volumn 156, Issue 4, 1999, Pages 564-568

  Aylward, Elizabeth H ^a   Li, Qiang ^b   Honeycutt, Nancy A ^b   Warren, Andrew C ^b   Pulsifer, Margaret B ^b   Barta, Patrick E ^b   Chan, Michael D ^b   Smith, Paige D ^b   Jerram, Matthew ^b   Pearlson, Godfrey D ^b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ARTICLE; BRAIN SCINTISCANNING; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DEMENTIA; DISEASE ASSOCIATION; DOWN SYNDROME; HIPPOCAMPUS; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

EID: 0032927816     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Brun A, Englund E: Regional pattern of degeneration in Alzheimer's disease: neuronal loss and histopathological grading. Histopathology 1981; 5:549-564
2. Pearson RC, Esiri MM, Hiorns RW, Wilcock GK, Powell TP: Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease. Proc Natl Acad Sci USA 1985; 82:4531-4534
3. Herzog AG, Kemper TL: Amygdaloid changes in aging and dementia. Arch Neurol 1980; 37:625-629
4. Wisniewski KE, Wisniewski HM, Wen GY: Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome. Ann Neurol 1985; 17:278-282
5. De la Monte SM, Hedley-Whyte ET: Small cerebral hemispheres in adults with Down's syndrome: contributions of developmental arrest and lesions of Alzheimer's disease. J Neuropathol Exp Neurol 1990; 49:509-520
6. Jernigan TL, Bellugi U, Sowell E, Doherty S, Hesselink JR: Cerebral morphologic distinctions between Williams and Down syndromes. Arch Neurol 1993; 50:186-191
7. Raz N, Torres IJ, Briggs SD, Spencer WD, Thornton AE, Loken WJ, Gunning FM, McQuain JD, Driesen NR, Acker JD: Selective neuroanatomic abnormalities in Down's syndrome and their cognitive correlates: evidence from MRI morphometry. Neurology 1995; 45:356-366
8. Kesslak JP, Nagata SF, Lott I, Nalcioglu O: Magnetic resonance imaging analysis of age-related changes in the brains of individuals with Down's syndrome. Neurology 1994; 44: 1039-1045
9. Prasher VP, Barber PD, Glenholmes P: The role of magnetic resonance imaging in the diagnosis of Alzheimer disease in adults with Down syndrome. Arch Neurol 1996; 53:1310-1313
10. Lai F, Williams RS: A prospective study of Alzheimer disease in Down syndrome. Arch Neurol 1989; 46:849-853
11. Pearlson GD, Warren AC, Starkstein SE, Aylward EH, Kumar AJ, Chase GA, Folstein MF: Brain atrophy in 18 patients with Down syndrome: a CT study. AJNR Am J Neuroradiol 1990; 11:811-816
12. Schapiro MB, Haxby JV, Grady CL: Nature of mental retardation and dementia in Down syndrome: study with PET, CT and neuropsychology. Neurobiol Aging 1992; 13:723-734
13. Schapiro MB, Luxenberg JS, Kaye JA, Haxby JV, Friedland RP, Rapoport SI: Serial quantitative CT analysis of brain morphometrics in adult Down's syndrome at different ages. Neurology 1989; 39:1349-1353
14. Lott IT, Lai FL: Dementia in Down syndrome (abstract). Ann Neurol 1982; 12:210
15. LeMay M, Alvarez N: The relationship between enlargement of the temporal horns of the lateral ventricles and dementia in aging patients with Down syndrome. Neuroradiology 1990; 32:104-107
16. Devinsky O, Sato S, Conwit RA, Schapiro MB: Relation of EEG alpha background to cognitive function, brain atrophy, and cerebral metabolism in Down's syndrome: age-specific changes. Arch Neurol 1990; 47:58-62
17. Gedye A: Dementia Scale for Down Syndrome Manual. Vancouver, BC, Gedye Research and Consulting, 1995
18. Aylward E, Li Q, Habbak R, Warren A, Pulsifer M, Barta P, Jerram M, Pearlson G: Basal ganglia volume in adults with Down syndrome. Psychiatry Res 1997; 74:73-82
19. Aylward E, Codori A, Barta P, Pearlson GP, Harris GJ, Brandt J: Basal ganglia volume and proximity to onset in presymptomatic Huntington's disease. Arch Neurol 1996; 53:1293-1296
20. Aylward EH, Anderson NB, Bylsma FW, Wagster MV, Barta PE, Sherr M, Feeney J, Davis A, Rosenblatt A, Pearlson GD, Ross CA: Frontal lobe volume in patients with Huntington's disease. Neurology 1998; 50:252-258
21. Jobst KA, Smith AD, Szatmari M, Esiri MM, Jaskowski A, Hindley N, McDonald B, Molyneux AJ: Rapidly progressing atrophy of medial temporal lobe in Alzheimer's disease. Lancet 1994; 343:829-830