The anti-inflammatory effect of algae-derived lipid extracts on lipopolysaccharide (LPS)-stimulated human THP-1 macrophages

Marine Drugs

Volumn 13, Issue 8, 2015, Pages 5402-5424

  Robertson, Ruairi C ^a,b   Guihéneuf, Freddy ^c   Bahar, Bojlul ^d   Schmid, Matthias ^c   Stengel, Dagmar B ^c   Fitzgerald, Gerald F ^b,e   Ross, R Paul ^b,e   Stanton, Catherine ^a,e  

^a TEAGASC FOOD RESEARCH CENTRE   (Ireland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^d UNIVERSITY COLLEGE DUBLIN   (Ireland)

^e UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Bioactive pigments; Chlorophyll a; Inflammation; Lipids; Macroalgae; Macrophages; Microalgae; N 3 PUFA; Polyunsaturated fatty acids; THP 1

Indexed keywords

ALGAL EXTRACT; ANTIINFLAMMATORY AGENT; BETA CAROTENE; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR4; CHLOROPHYLL A; CHONDRUS CRISPUS EXTRACT; FATTY ACID DERIVATIVE; FUCOXANTHIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN 8; LIPID; LIPOPOLYSACCHARIDE; OMEGA 3 FATTY ACID; PALMARIA PALMATA EXTRACT; PAVLOVA LUTHERI EXTRACT; PORPHYRA DIOICA EXTRACT; SATURATED FATTY ACID; STAT3 PROTEIN; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 5; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; UNINDEXED DRUG; TOLL LIKE RECEPTOR;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CCL17 GENE; CCR1 GENE; CCR4 GENE; CELL LINE; CHONDRUS CRISPUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG ISOLATION; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IL23 GENE; IL6R GENE; MACROPHAGE ACTIVATION; MAP3K1 GENE; MICROALGA; NONHUMAN; PALMARIA PALMATA; PAVLOVA LUTHERI; PORPHYRA DIOICA; PROTEIN SYNTHESIS INHIBITION; QUANTITATIVE ANALYSIS; SEAWEED; SIGNAL TRANSDUCTION; STAT3 GENE; THP 1 CELL; TLR1 GENE; TLR2 GENE; TLR4 GENE; TLR8 GENE; TNFSF18 GENE; TRAF5 GENE; TRAF6 GENE; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; MACROPHAGE; METABOLISM; RED ALGA;

ALGAE; CHONDRUS CRISPUS; PALMARIA PALMATA; PAVLOVA LUTHERI; PORPHYRA DIOICA;

ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; DOWN-REGULATION; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; LIPIDS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICROALGAE; NF-KAPPA B; RHODOPHYTA; SEAWEED; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84940383819     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md13085402     Document Type: Article

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