Nerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to Epac

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Vasko, Michael R ^a   Habashy Malty, Ramy ^a,b   Guo, Chunlu ^a   Duarte, Djane B ^c   Zhang, Yihong ^a   Nicol, Grant D ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Ain Shams University   (Egypt)

^c UNIVERSITY OF BRASILIA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CYCLIC AMP 1; EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CYCLIC AMP 2; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR ANTIBODY; POTASSIUM; PROSTAGLANDIN E2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; EPAC PROTEIN, RAT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN KINASE INHIBITOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; ENZYME INHIBITION; EVOKED RESPONSE; INFLAMMATION; INTRACELLULAR SIGNALING; MALE; NERVE CELL CULTURE; NERVE CELL EXCITABILITY; NONHUMAN; PROTEIN EXPRESSION; RAT; SENSITIZATION; SENSORY NERVE CELL; SPINAL CORD; SPINAL GANGLION; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; ENZYME ACTIVATION; GANGLIA, SPINAL; GENE EXPRESSION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INFLAMMATION; MALE; NERVE GROWTH FACTOR; PROTEIN KINASE INHIBITORS; RATS; SENSORY RECEPTOR CELLS; SIGNAL TRANSDUCTION; SPINAL CORD;

EID: 84940288051     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0104529     Document Type: Article

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