The role of glycyrrhetinic acid modification on preparation and evaluation of quercetin-loaded chitosan-based self-aggregates

Journal of Colloid and Interface Science

Volumn 460, Issue , 2015, Pages 87-96

  Du, Hongliang ^a   Liu, Mengrui ^a   Yang, Xiaoye ^a   Zhai, Guangxi ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Cell apoptosis; Cell cytotoxicity; Chitosan; Drug release; Glycyrrhetinic acid; Pharmacokinetics; Quercetin; Self aggregates; Zeta potential

Indexed keywords

BIOCHEMISTRY; CELL DEATH; CELLS; CHITIN; CHITOSAN; CYTOLOGY; DYNAMIC LIGHT SCATTERING; FLAVONOIDS; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; LIGHT SCATTERING; PHARMACOKINETICS; PHENOLS; RESIDENCE TIME DISTRIBUTION; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET VISIBLE SPECTROSCOPY; ZETA POTENTIAL;

CELL APOPTOSIS; DRUG RELEASE; GLYCYRRHETINIC ACIDS; QUERCETIN; SELF-AGGREGATES;

AGGREGATES;

CHITOSAN; CHOLIC ACID; GLYCYRRHETINIC ACID; NANOCARRIER; O CARBOXYMETHYLCHITOSAN; QUERCETIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DRUG CARRIER; NANOPARTICLE; O-CARBOXYMETHYLCHITOSAN;

ANIMAL EXPERIMENT; APOPTOSIS; AREA UNDER THE CURVE; ARTICLE; CELL STRUCTURE; CHEMICAL MODIFICATION; CONJUGATE; CONTROLLED STUDY; CYTOTOXICITY; DIALYSIS; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG FORMULATION; DRUG RELEASE; DYNAMIC LIGHT SCATTERING ANALYSIS; ELIMINATION HALF-LIFE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MALE; MEAN RESIDENCE TIME; NANOFABRICATION; NONHUMAN; PARTICLE SIZE; PH; PLASMA CLEARANCE; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY; ULTRASOUND; ULTRAVIOLET SPECTROSCOPY; ZETA POTENTIAL; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DRUG DESIGN; HEPG2 CELL LINE; PRECLINICAL STUDY; SPECTROPHOTOMETRY; ULTRAVIOLET SPECTROPHOTOMETRY; WISTAR RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CHITOSAN; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; DRUG LIBERATION; GLYCYRRHETINIC ACID; HEP G2 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; QUERCETIN; RATS; RATS, WISTAR; SPECTROPHOTOMETRY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84940062505     PISSN: 00219797     EISSN: 10957103     Source Type: Journal    
DOI: 10.1016/j.jcis.2015.08.049     Document Type: Article

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