Connecting the retina to the brain

ASN Neuro

Volumn 6, Issue 6, 2015, Pages

  Erskine, Lynda ^a   Herreral, Eloisa ^b  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b INSTITUTO DE NEUROCIENCIAS   (Spain)

Author keywords

Axon guidance; Growth cone; Optic chiasm; Retinal ganglion cell; Topographic mapping; Visual system

Indexed keywords

BETA INTEGRIN; CYCLIC AMP; EPHRIN RECEPTOR B1; FIBROBLAST GROWTH FACTOR 3; FIBROBLAST GROWTH FACTOR 8; NERVE CELL ADHESION MOLECULE; PROTEIN KINASE C ALPHA;

ALBINISM; ARTICLE; BRAIN; BRAIN MAPPING; CELL DIFFERENTIATION; DIENCEPHALON; HUMAN; NERVE CONDUCTION; NERVE ENDING; NERVE FIBER GROWTH; OPTIC CHIASM; OPTIC NERVE FIBER; OPTIC TRACT; RETINA; RETINA GANGLION CELL; STRIATE CORTEX; SUPERIOR COLLICULUS; VISUAL SYSTEM FUNCTION; ANIMAL; PHYSIOLOGY; VISUAL SYSTEM;

ANIMALS; BRAIN; HUMANS; RETINA; VISUAL PATHWAYS;

EID: 84940052515     PISSN: None     EISSN: 17590914     Source Type: Journal    
DOI: 10.1177/1759091414562107     Document Type: Article

References (258)

1. Ackman, J. B., Burbridge, T. J., & Crair, M. C. (2012). Retinal waves coordinate patterned activity throughout the developing visual system. Nature, 490, 219–225.
2. Antinucci, P., Nikolaou, N., Meyer, M. P., & Hindges, R. (2013). Teneurin-3 specifies morphological and functional connectivity of retinal ganglion cells in the vertebrate visual system. Cell Reports, 5, 582–592.
3. Apkarian, P., & Bour, L. J. (2001). See-saw nystagmus and congenital nystagmus identified in the non-decussating retinal-fugal fiber syndrome. Strabismus, 9, 143–163.
4. Apkarian, P., Bour, L., & Barth, P. G. (1994). A unique achiasmatic anomaly detected in non-albinos with misrouted retinal-fugal projections. European Journal of Neuroscience, 6, 501–507.
5. Apkarian, P., Bour, L. J., Barth, P. G., Wenniger-Prick, L., & Verbeeten, B. (1995). Non-decussating retinal-fugal fibre syndrome. An inborn achiasmatic malformation associated with visuotopic misrouting, visual evoked potential ipsilateral asymmetry and nystagmus. Brain: A Journal of Neurology, 118(Pt. 5): 1195–1216.
6. Atkinson-Leadbeater, K., Bertolesi, G. E., Hehr, C. L., Webber, C. A., Cechmanek, P. B., & McFarlane, S. (2010). Dynamic expression of axon guidance cues required for optic tract development is controlled by fibroblast growth factor signaling. Journal of Neuroscience, 30, 685–693.
7. Austin, C. P., Feldman, D. E., Ida, J. A. Jr., & Cepko, C. L. (1995). Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch. Development, 121, 3637–3650.
8. Badea, T. C., Cahill, H., Ecker, J., Hattar, S., & Nathans, J. (2009). Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells. Neuron, 61, 852–864.
9. Bansal, A., Singer, J. H., Hwang, B. J., Xu, W., Beaudet, A., & Feller, M. B. (2000). Mice lacking specific nicotinic acetylcholine receptor subunits exhibit dramatically altered spontaneous activity patterns and reveal a limited role for retinal waves in forming ON and OFF circuits in the inner retina. Journal of Neuroscience, 20, 7672–7681.
10. Barbieri, A. M., Broccoli, V., Bovolenta, P., Alfano, G., Marchitiello, A., Mocchetti, C., Banfi, S. (2002). Vax2 inactivation in mouse determines alteration of the eye dorsalventral axis, misrouting of the optic fibres and eye coloboma. Development, 129, 805–813.
11. Baudet, M. L., Zivraj, K. H., Abreu-Goodger, C., Muldal, A., Armisen, J., Blenkiron, C., Holt, C. E. (2012). miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones. Nature Neuroscience, 15, 29–38.
12. Becker, C. G., Schweitzer, J., Feldner, J., Becker, T., & Schachner, M. (2003). Tenascin-R as a repellent guidance molecule for developing optic axons in zebrafish. Journal of Neuroscience, 23, 6232–6237.
13. Behesti, H., Holt, J. K., & Sowden, J. C. (2006). The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup. BMC Developmental Biology, 6, 62.
14. Behesti, H., Papaioannou, V. E., & Sowden, J. C. (2009). Loss of Tbx2 delays optic vesicle invagination leading to small optic cups. Developmental Biology, 333, 360–372.
15. Benjumeda, I., Escalante, A., Law, C., Morales, D., Chauvin, G., Muca, G., Herrera, E. (2013). Uncoupling of EphA/ephrinA signaling and spontaneous activity in neural circuit wiring. Journal of Neuroscience, 33, 18208–18218.
16. Bertuzzi, S., Hindges, R., Mui, S. H., O’Leary, D. D., & Lemke, G. (1999). The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. Genes & Development, 13, 3092–3105.
17. Bhansali, P., Rayport, I., Rebsam, A., & Mason, C. (2014). Delayed neurogenesis leads to altered specification of ventrotemporal retinal ganglion cells in albino mice. Neural Development, 9, 11.
18. Birgbauer, E., Cowan, C. A., Sretavan, D. W., & Henkemeyer, M. (2000). Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development, 127, 1231–1241.
19. Bouhelal, R., Smounya, L., & Bockaert, J. (1988). 5-HT1B receptors are negatively coupled with adenylate cyclase in rat substantia nigra. European Journal of Pharmacology, 151, 189–196.
20. Brittis, P. A., Canning, D. R., & Silver, J. (1992). Chondroitin sulfate as a regulator of neuronal patterning in the retina. Science, 255, 733–736.
21. Brittis, P. A., Lemmon, V., Rutishauser, U., & Silver, J. (1995). Unique changes of ganglion cell growth cone behavior following cell adhesion molecule perturbations: A time-lapse study of the living retina. Molecular and Cellular Neuroscience, 6, 433–449.
22. Brittis, P. A., & Silver, J. (1994). Exogenous glycosaminoglycans induce complete inversion of retinal ganglion cell bodies and their axons within the retinal neuroepithelium. Proceedings of the National Academy of Sciences of the United States of America, 91, 7539–7542.
23. Brittis, P. A., & Silver, J. (1995). Multiple factors govern intr aretinal axon guidance: A time-lapse study. Molecular and Cellular Neuroscience, 6, 413–432.
24. Brown, A., Yates, P. A., Burrola, P., Ortuno, D., Vaidya, A., Jessell, T. M., Lemke, G. (2000). Topographic mapping from the retina to the midbrain is controlled by relative butnot absolute levels of EphA receptor signaling. Cell, 102, 77–88.
25. Brown, N. L., Patel, S., Brzezinski, J., & Glaser, T. (2001). Math5 is required for retinal ganglion cell and optic nerve formation. Development, 128, 2497–2508.
26. Brunet, I., Weinl, C., Piper, M., Trembleau, A., Volovitch, M., Harris, W., Holt, C. (2005). The transcription factor Engrailed-2 guides retinal axons. Nature, 438, 94–98.
27. Buhusi, M., Demyanenko, G. P., Jannie, K. M., Dalal, J., Darnell, E. P., Weiner, J. A., Maness, P. F. (2009). ALCAM regulates mediolateral retinotopic mapping in the superior colliculus. Journal of Neuroscience, 29, 15630–15641.
28. Campbell, D. S., Regan, A. G., Lopez, J. S., Tannahill, D., Harris, W. A., & Holt, C. E. (2001). Semaphorin 3A elicits stagedependent collapse, turning, and branching in Xenopus retinal growth cones. Journal of Neuroscience, 21, 8538–8547.
29. Cardozo, M. J., Sanchez-Arrones, L., Sandonis, A., Sanchez- Camacho, C., Gestri, G., Wilson, S. W., Bovolenta, P. (2014). Cdon acts as a Hedgehog decoy receptor during proximal- distal patterning of the optic vesicle. Nature Communications, 5, 4272.
30. Carreres, M. I., Escalante, A., Murillo, B., Chauvin, G., Gaspar, P., Vegar, C., Herrera, E. (2011). Transcription factor Foxd1 is required for the specification of the temporal retina in mammals. Journal of Neuroscience, 31, 5673–5681.
31. Carvalho, R. F., Beutler, M., Marler, K. J., Knoll, B., Becker-Barroso, E., Heintzmann, R., Drescher, U. (2006). Silencing of EphA3 through a cis interaction with ephrinA5. Nature Neuroscience, 9, 322–330.
32. Chalasani, S. H., Sabelko, K. A., Sunshine, M. J., Littman, D. R., & Raper, J. A. (2003). A chemokine, SDF-1, reduces the effectiveness of multiple axonal repellents and is requir ed for normal axon pathfinding. Journal of Neuroscience, 23, 1360–1371.
33. Chalasani, S. H., Sabol, A., Xu, H., Gyda, M. A., Rasband, K., Granato, M., Raper, J. A. (2007). Stromal cell-derived factor-1 antagonizes slit/robo signaling in vivo. Journal of Neuroscience, 27, 973–980.
34. Chalupa, L. M., & Snider, C. J. (1998). Topographic specificity in the retinocollicular projection of the developing ferret: An anterograde tracing study. Journal of Comparative Neurology, 392, 35–47.
35. Chan, S. O., & Guillery, R. W. (1994). Changes in fiber order in the optic nerve and tract of rat embryos. Journal of Comparative Neurology, 344, 20–32.
36. Chandrasekaran, A. R., Plas, D. T., Gonzalez, E., & Crair, M. C. (2005). Evidence for an instructive role of retinal activity in retinotopic map refinement in the superior colliculus of the mouse. Journal of Neuroscience, 25, 6929–6938.
37. Chapman, B., & Stone, L. S. (1996). Turning a blind eye to cortical receptive fields. Neuron, 16, 9–12.
38. Chapman, B., Stryker, M. P., & Bonhoeffer, T. (1996a). Development of orientation preference maps in ferret primary visual cortex. Journal of Neuroscience, 16, 6443–6453.
39. Chapman, D. L., Garvey, N., Hancock, S., Alexiou, M., Agulnik, S. I., Gibson-Brown, J. J., Papaioannou, V. E. (1996b). Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development. Developmental Dynamics: An Official Publication of the American Association of Anatomists, 206, 379–390.
40. Charron, F., Stein, E., Jeong, J., McMahon, A. P., & Tessier- Lavigne, M. (2003). The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell, 113, 11–23.
41. Chenaux, G., & Henkemeyer, M. (2011). Forward signaling by EphB1/EphB2 interacting with ephrin-B ligands at the optic chiasm is required to form the ipsilateral projection. European Journal of Neuroscience, 34, 1620–1633.
42. Chung, K. Y., Taylor, J. S., Shum, D. K., & Chan, S. O. (2000).Axon routing at the optic chiasm after enzymatic removal of chondroitin sulfate in mouse embryos. Development, 127, 2673–2683.
43. Colello, R. J., & Guillery, R. W. (1992). Observations on the early development of the optic nerve and tract of the mouse. Journal of Comparative Neurology, 317, 357–378.
44. Colello, S. J., & Guillery, R. W. (1998). The changing pattern of fibre bundles that pass through the optic chiasm of mice. European Journal of Neuroscience, 10, 3653–3663.
45. Conway, C. D., Howe, K. M., Nettleton, N. K., Price, D. J., Mason, J. O., & Pratt, T. (2011). Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development. Journal of Neuroscience, 31, 1955–1970.
46. Cook, P. M., Prusky, G., & Ramoa, A. S. (1999). The role of spontaneous retinal activity before eye opening in the maturation of form and function in the retinogeniculate pathway of the ferret. Visual Neuroscience, 16, 491–501.
47. Coombs, J. L., Van Der List, D., & Chalupa, L. M. (2007). Morphological properties of mouse retinal ganglion cells during postnatal development. Journal of Comparative Neurology, 503, 803–814.
48. Dai, J., Dalal, J. S., Thakar, S., Henkemeyer, M., Lemmon, V. P., Harunaga, J. S., Maness, P. F. (2012). EphB regulates L1 phosphorylation during retinocollicular mapping. Molecular and Cellular Neuroscience, 50, 201–210.
49. Dakubo, G. D., Wang, Y. P., Mazerolle, C., Campsall, K., McMahon, A. P., & Wallace, V. A. (2003). Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. Development, 130, 2967–2980.
50. Davis, N., Mor, E., & Ashery-Padan, R. (2011). Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium. Development, 138, 127–138.
51. Deiner, M. S., & Sretavan, D. W. (1999). Altered midline axon pathways and ectopic neurons in the developing hypothalamus of netrin-1- and DCC-deficient mice. Journal of Neuroscience, 19, 9900–9912.
52. Deiner, M. S., Kennedy, T. E., Fazeli, A., Serafini, T., Tessier-Lavigne, M., & Sretavan, D. W. (1997). Netrin-1 and DCC mediate axon guidance locally at the optic disc: Loss of function leads to optic nerve hypoplasia. Neuron, 19, 575–589.
53. de la Torre, J. R., Hopker, V. H., Ming, G. L., Poo, M. M., Tessier- Lavigne, M., Hemmati-Brivanlou, A., Holt, C. E. (1997). Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC. Neuron, 19, 1211–1224.
54. Dell, A. L., Fried-Cassorla, E., Xu, H., & Raper, J. A. (2013). cAMP-induced expression of neuropilin1 promotes retinal axon crossing in the zebrafish optic chiasm. Journal of Neuroscience, 33, 11076–11088.
55. Dell’Osso, L. F., Williams, R. W., Jacobs, J. B., & Erchul, D. M. (1998). The congenital and see-saw nystagmus in the prototypical achiasma of canines: Comparison to the human achiasmatic prototype. Vision Research, 38, 1629–1641.
56. Demas, J., Eglen, S. J., & Wong, R. O. (2003). Developmental loss of synchronous spontaneous activity in the mouse retina is independent of visual exp erience. Journal of Neuroscience, 23, 2851–2860.
57. Dhande, O. S., Bhatt, S., Anishchenko, A., Elstrott, J., Iwasato, T., Swindell, E. C., Crair, M. C. (2012). Role of adenylate cyclase 1 in retinofugal map development. Journal of Comparative Neurology, 520, 1562–1583.
58. Dhande, O. S., Hua, E. W., Guh, E., Yeh, J., Bhatt, S., Zhang, Y., Crair, M. C. (2011). Development of single retinofugal axon arbors in normal and beta2 knock-out mice. Journal of Neuroscience, 31, 3384–3399.
59. Dharmaratne, N., Glendining, K. A., Young, T. R., Tran, H., Sawatari, A., & Leamey, C. A. (2012). Ten-m3 is required for the development of topography in the ipsilateral retinocollicular pathway. PLoS One, 7, e43083.
60. Drager, U. C. (1985). Birth dates of retinal ganglion cells giving rise to the crossed and uncrossed optic projections in the mouse. Proceedings of the Royal Society of London B: Biological Sciences, 224, 57–77.
61. Erkman, L., Yates, P. A., McLaughlin, T., McEvilly, R. J., Whisenhunt, T., O’Connell, S. M., Rosenfeld, M. G. (2000). A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system. Neuron, 28, 779–792.
62. Erskine, L., Reijntjes, S., Pratt, T., Denti, L., Schwarz, Q., Vieira, J. M., Ruhrberg, C. (2011). VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm. Neuron, 70, 951–965.
63. Erskine, L., Williams, S. E., Brose, K., Kidd, T., Rachel, R. A., Goodman, C. S., Mason, C. A. (2000). Retinal ganglion cell axon guidance in the mouse optic chiasm: Expression and function of robos and slits. Journal of Neuroscience, 20, 4975–4982.
64. Escalante, A., Murillo, B., Morenilla-Palao, C., Klar, A., & Herrera, E. (2013). Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS. Neuron, 80, 1392–1406.
65. Esteve, P., Sandonis, A., Cardozo, M., Malapeira, J., Ibanez, C., Crespo, I., Bovolenta, P. (2011). SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis. Nature Neuroscience, 14, 562–569.
66. Fabre, P. J., Shimogori, T., & Charron, F. (2010). Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc. Journal of Neuroscience, 30, 266–275.
67. Feldheim, D. A., Kim, Y. I., Bergemann, A. D., Frisen, J., Barbacid, M., & Flanagan, J. G. (2000). Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping. Neuron, 25, 563–574.
68. Feldheim, D. A., Vanderhaeghen, P., Hansen, M. J., Frisen, J., Lu, Q., Barbacid, M., Flanagan, J. G. (1998). Topographic guid ancelabels in a sensory projection to the forebrain. Neuron, 21, 1303–1313.
69. Feller, M. B., Wellis, D. P., Stellwagen, D., Werblin, F. S., & Shatz, C. J. (1996). Requirement for cholinergic synaptic transmission in the propagation of spontaneous retinal waves. Science, 272, 1182–1187.
70. Fricke, C., Lee, J. S., Geiger-Rudolph, S., Bonhoeffer, F., & Chien, C. B. (2001). Astray, a zebrafish roundabout homolog required for retinal axon guidance. Science, 292, 507–510.
71. Frisen, J., Yates, P. A., McLaughlin, T., Friedman, G. C., O’Leary, D. D., & Barbacid, M. (1998). Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system. Neuron, 20, 235–243.
72. Garcia-Frigola, C., Carreres, M. I., Vegar, C., Mason, C., & Herrera, E. (2008). Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent an d -independentmechanisms. Development, 135, 1833–1841.
73. Garcia-Frigola, C., & Herrera, E. (2010). Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets. EMBO Journal, 29, 3170–3183.
74. Godement, P., Salaun, J., & Imbert, M. (1984). Prenatal and postn ataldevelopment of retinogeniculate and retinocollicular projections in the mouse. Journal of Comparative Neurology, 230, 552–575.
75. Gonzalez-Hoyuela, M., Barbas, J. A., & Rodriguez-Tebar, A. (2001). The autoregulation of retinal ganglion cell number. Development, 128, 117–124.
76. Gordon, L., Mansh, M., Kinsman, H., & Morris, A. R. (2010). Xenopus sonic hedgehog guides retinal axons along the optic tract. Developmental Dynamics: An Official Publication of the American Association of Anatomists, 239, 2921–2932.
77. Gross, J. M., & Dowling, J. E. (2005). Tbx2b is essential for neuronal differentiation along the dorsal/ventral axis of the zebrafish retina. Proceedings of the National Academy of Sciences of the United States of America, 102, 4371–4376.
78. Guo, D., Standley, C., Bellve, K., Fogarty, K., & Bao, Z. Z. (2012). Protein kinase Calpha and integrin-linked kinase mediate the negative axon guidance effects of Sonic hedgehog. Molecular and Cellular Neuroscience, 50, 82–92.
79. Halfter, W. (1996). Intraretinal grafting reveals growth requirements and guidance cues for optic axons in the developing avian retina. Developmental Biology, 177, 160–177.
80. Halfter, W., Reckhaus, W., & Kroger, S. (1987). Nondirected axonal growth on basal lamina from avian embryonic neural retina. Journal of Neuroscience, 7, 3712–3722.
81. Hashimoto, T., Zhang, X. M., Chen, B. Y., & Yang, X. J. (2006). VEGF activates divergent intracellular signaling components to regulate retinal progenitor cell proliferation and neuronal differentiation. Development, 133, 2201–2210.
82. Hehr, C. L., Hocking, J. C., & McFarlane, S. (2005). Matrix metalloproteinases are required for retinal ganglion cell axon guidance at select decision points. Development, 132, 3371–3379.
83. Henrique, D., Hirsinger, E., Adam, J., Le Roux, I., Pourquie, O., Ish-Horowicz, D., Lewis, J. (1997). Maintenance of neuroepithelial progenitor cells by Delta-Notch signalling in the embryonic chick retina. Current Biology, 7, 661–670.
84. Herrera, E., Brown, L., Aruga, J., Rachel, R. A., Dolen, G., Mikoshiba, K., Mason, C. A. (2003). Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell, 114, 545–557.
85. Herrera, E., Marcus, R., Li, S., Williams, S. E., Erskine, L., Lai, E., Mason, C. (2004). Foxd1 is required for proper formation of the optic chiasm. Development, 131, 5727–5739.
86. Hindges, R., McLaughlin, T., Genoud, N., Henkemeyer, M., & O’Leary, D. (2002). EphB forward signaling controls directional branch extension and arborization required for dorsal-ventral retinotopic mapping. Neuron, 35, 475–487.
87. Hinds, J. W., & Hinds, P. L. (1974). Early ganglion cell differentiation in the mouse retina: An electron microscopic analysis utilizing serial sections. Developmental Biology, 37, 381–416.
88. Hoffmann, M. B., Kaule, F. R., Levin, N., Masuda, Y., Kumar, A., Gottlob, I., Dumoulin, S. O. (2012). Plasticity and stability of the visual system in human achiasma. Neuron, 75, 393–401.
89. Holt, C. E. (1989). A single-cell analysis of early retinal ganglion cell differentiation in Xenopus: From soma to axon tip. Journal of Neuroscience, 9, 3123–3145.
90. Holt, C. E., Bertsch, T. W., Ellis, H. M., & Harris, W. A. (1988). Cellular determination in the Xenopus retina is independent of lineage and birth date. Neuron, 1, 15–26.
91. Hopker, V. H., Shewan, D., Tessier-Lavigne, M., Poo, M., & Holt, C. (1999). Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1. Nature, 401, 69–73.
92. Hornberger, M. R., Dutting, D., Ciossek, T., Yamada, T., Handwerker, C., Lang, S., Drescher, U. (1999). Modulation of EphA receptor function by coexpressed ephrinA ligands on retinal ganglion cell axons. Neuron, 22, 731–742.
93. Hu, M., & Easter, S. S. (1999). Retinal neurogenesis: The formation of the initial central patch of postmitotic cells. Developmental Biology, 207, 309–321.
94. Huang, Y. Y., Rinner, O., Hedinger, P., Liu, S. C., & Neuhauss, S. C. (2006). Oculomotor instabilities in zebrafish mutant belladonna: A behavioral model for congenital nystagmus caused by axonal misrouting. Journal of Neuroscience, 26, 9873–9880.
95. Hufnagel, R. B., Le, T. T., Riesenberg, A. L., & Brown, N. L. (2010). Neurog2 controls the leading edge of neurogenesis in the mammalian retina. Developmental Biology, 340, 490–503.
96. Hutson, L. D., & Chien, C. B. (2002). Pathfinding and error correction by retinal axons: The role of astray/robo2. Neuron, 33, 205–217.
97. Ichijo, H., & Kawabata, I. (2001). Roles of the telencephalic cells and their chondroitin sulfate proteoglycans in delimiting an anterior border of the retinal pathway. Journal of Neuroscience, 21, 9304–9314.
98. Ilia, M., & Jeffery, G. (1999). Retinal mitosis is regulated by dopa, a melanin precursor that may influence the time at which cells exit the cell cycle: Analysis of patterns of cell production in pigmented and albino retinae. Journal of Comparative Neurology, 405, 394–405.
99. Imai, T., Suzuki, M., & Sakano, H. (2006). Odorant receptorderived cAMP signals direct axonal targeting. Science, 314, 657–661.
100. Inatani, M., Irie, F., Plump, A. S., Tessier-Lavigne, M., & Yamaguchi, Y. (2003). Mammalian brain morphogenesis and midline axon guidance require heparan sulfate. Science, 302, 1044–1046.
101. Irie, A., Yates, E. A., Turnbull, J. E., & Holt, C. E. (2002). Specific heparan sulfate structures involved in retinal axon targeting. Development, 129, 61–70.
102. Issa, N. P., Trachtenberg, J. T., Chapman, B., Zahs, K. R., & Stryker, M. P. (1999). The critical period for ocular dominance plasticity in the Ferret’s visual cortex. Journal of Neuroscience, 19, 6965–6978.
103. Jeffery, G., & Erskine, L. (2005). Variations in the architecture and development of the vertebrate optic chiasm. Progress in Retinal and Eye Research, 24, 721–753.
104. Kamaraj, B., & Purohit, R. (2014). Mutational analysis of oculocutaneous albinism: A compact review. BioMed Research International, 2014, 905472.
105. Kaule, F. R., Wolynski, B., Gottlob, I., Stadler, J., Speck, O., Kanowski, M., Hoffmann, M. B. (2014). Impact of chiasma opticum malformations on the organization of the human ventral visual cortex. Human Brain Mapping, 35, 5093–5105.
106. Kennedy, T. E., Serafini, T., de la Torre, J. R., & Tessier-Lavigne, M. (1994). Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord. Cell, 78, 425–435.
107. Kim, J., Wu, H. H., Lander, A. D., Lyons, K. M., Matzuk, M. M., & Calof, A. L. (2005). GDF11 controls the timing of progenitor cell competence in developing retina. Science, 308, 1927–1930.
108. Kim, N., Min, K. W., Kang, K. H., Lee, E. J., Kim, H. T., Moon, K., Kim, J. W. (2014). Regulation of retinal axon growth by secreted Vax1 homeodomain protein. ELife, 3, e02671.
109. Koch, S. M., & Ullian, E. M. (2010). Neuronal pentraxins mediate silent synapse conversion in the developing visual system. Journal of Neuroscience, 30, 5404–5414.
110. Kolpak, A., Zhang, J., & Bao, Z. Z. (2005). Sonic hedgehog has a dual effect on the growth of retinal ganglion axons depending on its concentration. Journal of Neuroscience, 25, 3432–3441.
111. Koshiba-Takeuchi, K., Takeuchi, J. K., Matsumoto, K., Momose, T., Uno, K., Hoepker, V., Ogura, T. (2000). Tbx5 and the retinotectum projection. Science, 287, 134–137.
112. Kralj-Hans, I., Tibber, M., Jeffery, G., & Mobbs, P. (2006). Differential effect of dopamine on mitosis in early postnatal albino and pigmented rat retinae. Journal of Neurobiology, 66, 47–55.
113. Kruger, K., Tam, A. S., Lu, C., & Sretavan, D. W. (1998). Retinal ganglion cell axon progression from the optic chiasm to initiate optic tract development requires cell autonomous function of GAP-43. Journal of Neuroscience, 18, 5692–5705.
114. Kuwajima, T., Yoshida, Y., Takegahara, N., Petros, T. J., Kumanogoh, A., Jessell, T. M., Mason, C. (2012). Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing. Neuron, 74, 676–690.
115. Leamey, C. A., Merlin, S., Lattouf, P., Sawatari, A., Zhou, X., Demel, N., Fassler, R. (2007). Ten_m3 regulates eye-specific patterning in the mammalian visual pathway and is required for binocular vision. PLoS Biology, 5, e241.
116. Lee, J. S., von der Hardt, S., Rusch, M. A., Stringer, S. E., Stickney, H. L., Talbot, W. S., Roehl, H. (2004). Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer). Neuron, 44, 947–960.
117. Leung, L. C., Urbancic, V., Baudet, M. L., Dwivedy, A., Bayley, T. G., Lee, A. C., Holt, C. E. (2013). Coupling of NF-protocadherin signaling to axon guidance by cue-induced translation. Nature Neuroscience, 16, 166–173.
118. Li, Q., Shirabe, K., Thisse, C., Thisse, B., Okamoto, H., Masai, I., Kuwada, J. Y. (2005). Chemokine signaling guides axons within the retina in zebrafish. Journal of Neuroscience, 25, 1711–1717.
119. Lilienbaum, A., Reszka, A. A., Horwitz, A. F., & Holt, C. E. (1995). Chimeric integrins expressed in retinal ganglion cells impair process outgrowth in vivo. Molecular and Cellular Neuroscience, 6, 139–152.
120. Lim, Y. S., McLaughlin, T., Sung, T. C., Santiago, A., Lee, K. F., & O’Leary, D. D. (2008). p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping. Neuron, 59, 746–758.
121. Liu, J., Wilson, S., & Reh, T. (2003). BMP receptor 1b is required for axon guidance and cell survival in the developing retina. Developmental Biology, 256, 34–48.
122. Macdonald, R., Scholes, J., Strahle, U., Brennan, C., Holder, N., Brand, M., Wilson, S. W. (1997). The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain. Development, 124, 2397–2408.
123. Maiorano, N. A., & Hindges, R. (2013). Restricted perinatal retinal degeneration induces retina reshaping and correlated structural rearrangement of the retinotopic map. Nature Communications, 4, 1938.
124. Mann, F., Ray, S., Harris, W., & Holt, C. (2002). Topographic mapping in dorsoventral axis of the Xenopus retinotectal system depends on signaling through ephrin-B ligands. Neuron, 35, 461–473.
125. Manuel, M., Pratt, T., Liu, M., Jeffery, G., & Price, D. J. (2008). Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Developmental Biology, 8, 59.
126. Marcus, R. C., Blazeski, R., Godement, P., & Mason, C. A. (1995). Retinal axon divergence in the optic chiasm: Uncrossed axons diverge from crossed axons within a midline glial specialization. Journal of Neuroscience, 15, 3716–3729.
127. Marcus, R. C., Gale, N. W., Morrison, M. E., Mason, C. A., & Yancopoulos, G. D. (1996). Eph family receptors and their ligands distribute in opposing gradients in the developing mouse retina. Developmental Biology, 180, 786–789.
128. Marcus, R. C., Shimamura, K., Sretavan, D., Lai, E., Rubenstein, J. L., & Mason, C. A. (1999). Domains of regulatory gene expression and the developing optic chiasm: Correspondence with retinal axon paths and candidate signaling cells. Journal of Comparative Neurology, 403, 346–358.
129. Marler, K. J., Becker-Barroso, E., Martinez, A., Llovera, M., Wentzel, C., Poopalasundaram, S., Drescher, U. (2008). A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis. Journal of Neuroscience, 28, 12700–12712.
130. Marler, K. J., Suetterlin, P., Dopplapudi, A., Rubikaite, A., Adnan, J., Maiorano, N. A., Drescher, U. (2013). BDNF promotes axon branching of retinal ganglion cells via miRNA-132 and p250GAP. Journal of Neuroscience, 34, 969–979.
131. Martinez-Garcia, M., & Montoliu, L. (2013). Albinism in Europe. Journal of Dermatology, 40, 319–324.
132. Martinez-Morales, J. R., Del Bene, F., Nica, G., Hammerschmidt, M., Bovolenta, P., & Wittbrodt, J. (2005). Differentiation of the vertebrate retina is coordinated by an FGF signaling center. Developmental Cell, 8, 565–574.
133. Masai, I., Stemple, D. L., Okamoto, H., & Wilson, S. W. (2000). Midline signals regulate retinal neurogenesis in zebrafish.Neuron, 27, 251–263.
134. Maurer, K. A., Riesenberg, A. N., & Brown, N. L. (2014). Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina. Development, 141, 3243–3254.
135. McCabe, K. L., Gunther, E. C., & Reh, T. A. (1999). The development of the pattern of retinal ganglion cells in the chick retina: Mechanisms that control differentiation. Development, 126, 5713–5724.
136. McFarlane, S., Cornel, E., Amaya, E., & Holt, C. E. (1996). Inhibition of FGF receptor activity in retinal ganglion cell axons causes errors in target recognition. Neuron, 17, 245–254.
137. McFarlane, S., McNeill, L., & Holt, C. E. (1995). FGF signaling and target recognition in the developing Xenopus visual system. Neuron, 15, 1017–1028.
138. McLaughlin, T., Hindges, R., & O’Leary, D. D. (2003a). Regulation of axial patterning of the retina and its topographic mapping in the brain. Current Opinion in Neurobiology, 13, 57–69.
139. McLaughlin, T., Hindges, R., Yates, P. A., & O’Leary, D. D. (2003b). Bifunctional action of ephrin-B1 as a repellent and attractant to control bidirectional branch extension in dorsalventral retinotopic mapping. Development, 130, 2407–2418.
140. McLaughlin, T., Lim, Y. S., Santiago, A., & O’Leary, D. D. (2014). Multiple EphB receptors mediate dorsal-ventral retinotopic mapping via similar bi-functional responses to ephrin-B1. Molecular and Cellular Neuroscience, 63C, 24–30.
141. McLoon, S. C., & Barnes, R. B. (1989). Early differentiation of retinal ganglion cells: An axonal protein expressed by premigratory and migrating retinal ganglion cells. Journal of Neuroscience, 9, 1424–1432.
142. Miller, E. D., Tran, M. N., Wong, G. K., Oakley, D. M., & Wong, R. O. (1999). Morphological differentiation of bipolar cells in the ferret retina. Visual Neuroscience, 16, 1133–1144.
143. Mui, S. H., Hindges, R., O’Leary, D. D., Lemke, G., & Bertuzzi, S. (2002). The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. Development, 129, 797–804.
144. Nakamoto, C., Kuan, S. L., Findlay, A. S., Durward, E., Ouyang, Z., Zakrzewska, E. D., Nakamoto, M. (2014). Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development. Molecular Biology of the Cell, 25, 234–244.
145. Nakamura, H., & O’Leary, D. D. (1989). Inaccuracies in initial growth and arborization of chick retinotectal axons followed by course corrections and axon remodeling to develop topographic order. Journal of Neuroscience, 9, 3776–3795.
146. Neumann, C. J., & Nuesslein-Volhard, C. (2000). Patterning of the zebrafish retina by a wave of sonic hedgehog activity. Science, 289, 2137–2139.
147. Niclou, S. P., Jia, L., & Raper, J. A. (2000). Slit2 is a repellent for retinal gang lion cell axons. Journal of Neuroscience, 20, 4962–4974.
148. Nicol, X., Voyatzis, S., Muzerelle, A., Narboux-Neme, N., Sudhof, T. C., Miles, R., Gaspar, P. (2007). cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map. Nature Neuroscience, 10, 340–347.
149. Ogata-Iwao, M., Inatani, M., Iwao, K., Takihara, Y., Nakaishi- Fukuchi, Y., Irie, F., Tanihara, H. (2011). Heparan sulfate regulates intraretinal axon pathfinding by retinal ganglion cells. Investigative Ophthalmology & Visual Science, 52, 6671–6679.
150. Ohta, K., Tannahill, D., Yoshida, K., Johnson, A. R., Cook, G. M., & Keynes, R. J. (1999). Embryonic lens repels retinal ganglion cell axons. Developmental Biology, 211, 124–132.
151. O’Leary, D. D., Crespo, D., Fawcett, J. W., & Cowan, W. M. (1986). The effect of intraocular tetrodotoxin on the postnatal reduction in the numbers of optic nerve axons in the rat. Brain Research, 395, 96–103.
152. Oster, S. F., Bodeker, M. O., He, F., & Sretavan, D. W. (2003). Invariant Sema5A inhibition serves an ensheathing function during optic nerve development. Development, 130, 775–784.
153. Osterhout, J. A., Josten, N., Yamada, J., Pan, F., Wu, S. W., Nguyen, P. L., Huberman, A. D. (2011). Cadherin-6 mediates axon-target matching in a non-image-forming visual circuit. Neuron, 71, 632–639.
154. Ott, H., Bastmeyer, M., & Stuermer, C. A. (1998). Neurolin, the goldfish homolog of DM-GRASP, is involved in retinal axon pathfinding to the optic disk. Journal of Neuroscience, 18, 3363–3372.
155. Otteson, D. C., Shelden, E., Jones, J. M., Kameoka, J., & Hitchcock, P. F. (1998). Pax2 expression and retinal morphogenesis in the normal and Krd mouse. Developmental Biology, 193, 209–224.
156. Pacal, M., & Bremner, R. (2014). Induction of the ganglion cell differentiation program in human retinal progenitors before cell cycle exit. Developmental Dynamics: An Official Publication of the American Association of Anatomists, 243, 712–729.
157. Pak, W., Hindges, R., Lim, Y. S., Pfaff, S. L., & O’Leary, D. D. (2004). Magnitude of binocular vision controlled by islet-2 repression of a genetic program that specifies laterality of retinal axon pathfinding. Cell, 119, 567–578.
158. Pan, L., Deng, M., Xie, X., & Gan, L. (2008). ISL1 and BRN3B coregulate the differentiation of murine retinal ganglion cells. Development, 135, 1981–1990.
159. Pan, L., Yang, Z., Feng, L., & Gan, L. (2005). Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis. Development, 132, 703–712.
160. Penn, A. A., Riquelme, P. A., Feller, M. B., & Shatz, C. J. (1998). Competition in retinogeniculate patterning driven by spontaneous activity. Science, 279, 2108–2112.
161. Petros, T. J., Shrestha, B. R., & Mason, C. (2009). Specificity and sufficiency of EphB1 in driving the ipsilateral retinal projection. Journal of Neuroscience, 29, 3463–3474.
162. Pinter, R., & Hindges, R. (2010). Perturbations of microRNA function in mouse dicer mutants produce retinal defects and lead to aberrant axon pathfinding at the optic chiasm. PLoS One, 5, e10021.
163. Piper, M., Anderson, R., Dwivedy, A., Weinl, C., van Horck, F., Leung, K. M., Holt, C. (2006). Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones. Neuron, 49, 215–228.
164. Piper, M., Dwivedy, A., Leung, L., Bradley, R. S., & Holt, C. E. (2008). NF-protocadherin and TAF1 regulate retinal axon initiation and elongation in vivo. Journal of Neuroscience, 28, 100–105.
165. Plachez, C., Andrews, W., Liapi, A., Knoell, B., Drescher, U., Mankoo, B., Sundaresan, V. (2008). Robos are required for the correct targeting of retinal ganglion cell axons in the visual pathway of the brain. Molecular and Cellular Neuroscience, 37, 719–730.
166. Plump, A. S., Erskine, L., Sabatier, C., Brose, K., Epstein, C. J., Goodman, C. S., Tessier-Lavigne, M. (2002). Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system. Neuron, 33, 219–232.
167. Poulain, F. E., & Chien, C. B. (2013). Proteoglycan-mediated axon degeneration corrects pretarget topographic sorting errors. Neuron, 78, 49–56.
168. Prakash, S., Dumoulin, S. O., Fischbein, N., Wandell, B. A., & Liao, Y. J. (2010). Congenital achiasma and see-saw nystagmus in VACTERL syndrome. Journal of Neuro-Ophthalmology, 30, 45–48.
169. Prasov, L., & Glaser, T. (2012). Dynamic expression of ganglion cell markers in retinal progenitors during the terminal cell cycle. Molecular and Cellular Neuroscience, 50, 160–168.
170. Pratt, T., Conway, C. D., Tian, N. M., Price, D. J., & Mason, J. O. (2006). Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm. Journal of Neuroscience, 26, 6911–6923.
171. Pratt, T., Tian, N. M., Simpson, T. I., Mason, J. O., & Price, D. J. (2004). The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse. Development, 131, 3773–3784.
172. Rachel, R. A., Dolen, G., Hayes, N. L., Lu, A., Erskine, L., Nowakowski, R. S., Mason, C. A. (2002). Spatiotemporal features of early neuronogenesis differ in wild-type and albino mouse retina. Journal of Neuroscience, 22, 4249–4263.
173. Rakic, P. (1976). Prenatal genesis of connections subserving ocular dominance in the rhesus monkey. Nature, 261, 467–471.
174. Rashid, T., Upton, A. L., Blentic, A., Ciossek, T., Knoll, B., Thompson, I. D., Drescher, U. (2005). Opposing gradients of ephrin-As and EphA7 in the superior colliculus are essential for topographic mapping in the mammalian visual system. Neuron, 47, 57–69.
175. Reber, M., Burrola, P., & Lemke, G. (2004). A relative signalling model for the formation of a topographic neural map. Nature, 431, 847–853.
176. Rebsam, A., Bhansali, P., & Mason, C. A. (2012). Eye-specific projections of retinogeniculate axons are altered in albino mice. Journal of Neuroscience, 32, 4821–4826.
177. Rebsam, A., Petros, T. J., & Mason, C. A. (2009). Switching retinogeniculate axon laterality leads to normal targeting but abnormal eye-specific segregation that is activity dependent. Journal of Neuroscience, 29, 14855–14863.
178. Rhee, J., Mahfooz, N. S., Arregui, C., Lilien, J., Balsamo, J., & VanBerkum, M. F. (2002). Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion. Nature Cell Biology, 4, 798–805.
179. Rice, D. S., Tang, Q., Williams, R. W., Harris, B. S., Davisson, M. T., & Goldowitz, D. (1997). Decreased retinal ganglion cell number and misdirected axon growth associated with fissure defects in Bst/þ mutant mice. Investigative Ophthalmology & Visual Science, 38, 2112–2124.
180. Riehl, R., Johnson, K., Bradley, R., Grunwald, G. B., Cornel, E., Lilienbaum, A., Holt, C. E. (1996). Cadherin function is required for axon outgrowth in retinal ganglion cells in vivo. Neuron, 17, 837–848.
181. Ringstedt, T., Braisted, J. E., Brose, K., Kidd, T., Goodman, C., Tessier-Lavigne, M., O’Leary, D. D. (2000). Slit inhibition of retinal axon growth and its role in retinal axon pathfinding and innervation patterns in the diencephalon. Journal of Neuroscience, 20, 4983–4991.
182. Rodriguez, J., Esteve, P., Weinl, C., Ruiz, J. M., Fermin, Y., Trousse, F., Bovolenta, P. (2005). SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor. Nature Neuroscience, 8, 1301–1309.
183. Rossi, F. M., Pizzorusso, T., Porciatti, V., Marubio, L. M., Maffei, L., & Changeux, J. P. (2001). Requirement of the nicotinic acetylcholine receptor beta 2 subunit for the anatomical and functional development of the visual system. Proceedings of the National Academy of Sciences of the United States of America, 98, 6453–6458.
184. Ruchhoeft, M. L., Ohnuma, S., McNeill, L., Holt, C. E., & Harris, W. A. (1999). The neuronal architecture of Xenopus retinal ganglion cells is sculpted by rho-family GTPases in vivo. Journal of Neuroscience, 19, 8454–8463.
185. Sakai, J. A., & Halloran, M. C. (2006). Semaphorin 3d guides laterality of retinal ganglion cell projections in zebrafish. Development, 133, 1035–1044.
186. Salichon, N., Gaspar, P., Upton, A. L., Picaud, S., Hanoun, N., Hamon, M., Seif, I. (2001). Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice. Journal of Neuroscience, 21, 884–896.
187. Sanchez-Arrones, L., Nieto-Lopez, F., Sanchez-Camacho, C., Carreres, M. I., Herrera, E., Okada, A., Bovolenta, P. (2013). Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina. Journal of Neuroscience, 33, 8596–8607.
188. Sanchez-Camacho, C., & Bovolenta, P. (2008). Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons. Development, 135, 3531–3541.
189. Schmidt, T. M., Do, M. T., Dacey, D., Lucas, R., Hattar, S., & Matynia, A. (2011). Melanopsin-positive intrinsically photosensitive retinal ganglion cells: From form to function. Journal of Neuroscience, 31, 16094–16101.
190. Schmitt, A. M., Shi, J., Wolf, A. M., Lu, C. C., King, L. A., & Zou, Y. (2006). Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping. Nature, 439, 31–37.
191. Scholes, J. H. (1979). Nerve fibre topography in the retinal projection to the tectum. Nature, 278, 620–624.
192. Seth, A., Culverwell, J., Walkowicz, M., Toro, S., Rick, J. M., Neuhauss, S. C., Karlstrom, R. O. (2006). Belladonna (Ihx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain. Development, 133, 725–735.
193. Shanmugalingam, S., Houart, C., Picker, A., Reifers, F., Macdonald, R., Barth, A., Wilson, S. W. (2000). Ace/Fgf8 is required for forebrain commissure formation and patterning of the telencephalon. Development, 127, 2549–2561.
194. Shatz, C. J., & Sretavan, D. W. (1986). Interactions between retinal ganglion cells during the development of the mammalian visual system. Annual Review of Neuroscience, 9, 171–207.
195. Shewan, D., Dwivedy, A., Anderson, R., & Holt, C. E. (2002). Agerelated changes underlie switch in netrin-1 responsiveness as growth cones advance along visual pathway. Nature Neuroscience, 5, 955–962.
196. Shi, M., Kumar, S. R., Motajo, O., Kretschmer, F., Mu, X., & Badea, T. C. (2013). Genetic interactions between Brn3 transcription factors in retinal ganglion cell type specification. PLoS One, 8, e76347.
197. Silver, J. (1984). Studies on the factors that govern directionality of axonal growth in the embryonic optic nerve and at the chiasm of mice. Journal of Comparative Neurology, 223, 238–251.
198. Simon, D. K., & O’Leary, D. D. (1992). Development of topographic order in the mammalian retinocollicular projection. Journal of Neuroscience, 12, 1212–1232.
199. Snow, R. L., & Robson, J. A. (1994). Ganglion cell neurogenesis, migration and early differentiation in the chick retina. Neuroscience, 58, 399–409.
200. Song, H., Ming, G., He, Z., Lehmann, M., McKerracher, L., Tessier-Lavigne, M., Poo, M. (1998). Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides. Science, 281, 1515–1518.
201. Sowden, J. C., Holt, J. K., Meins, M., Smith, H. K., & Bhattacharya, S. S. (2001). Expression of Drosophila ombrelated T-box genes in the developing human and mouse neural retina. Investigative Ophthalmology & Visual Science, 42, 3095–3102.
202. Sretavan, D. W., Feng, L., Pure, E., & Reichardt, L. F. (1994). Embryonic neurons of the developing optic chiasm express L1 and CD44, cell surface molecules with opposing effects on retinal axon growth. Neuron, 12, 957–975.
203. Sretavan, D. W., & Kruger, K. (1998). Randomized retinal ganglion cell axon routing at the optic chiasm of GAP-43-deficient mice: Association with midline recrossing and lack of normal ipsilateral axon turning. Journal of Neuroscience, 18, 10502–10513.
204. Sretavan, D. W., Pure, E., Siegel, M. W., & Reichardt, L. F. (1995). Disruption of retinal axon ingrowth by ablation of embryonic mouse optic chiasm neurons. Science, 269, 98–101.
205. Stellwagen, D., & Shatz, C. J. (2002). An instructive role for retinal waves in the development of retinogeniculate connectivity. Neuron, 33, 357–367.
206. Stettler, O., Joshi, R. L., Wizenmann, A., Reingruber, J., Holcman, D., Bouillot, C., Moya, K. L. (2012). Engrailed homeoprotein recruits the adenosine A1 receptor to potentiate ephrin A5 function in retinal growth cones. Development, 139, 215–224.
207. Stevens, A., & Jacobs, J. R. (2002). Integrins regulate responsiveness to slit repellent signals. Journal of Neuroscience, 22, 4448–4455.
208. Stier, H., & Schlosshauer, B. (1995). Axonal guidance in the chicken retina. Development, 121, 1443–1454.
209. Stone, K. E., & Sakaguchi, D. S. (1996). Perturbation of the developing Xenopus retinotectal projection following injections of antibodies against beta1 integrin receptors and N-cadherin. Developmental Biology, 180, 297–310.
210. Strittmatter, S. M., Fankhauser, C., Huang, P. L., Mashimo, H., & Fishman, M. C. (1995). Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell, 80, 445–452.
211. Strochlic, L., Dwivedy, A., van Horck, F. P., Falk, J., & Holt, C. E. (2008). A role for S1P signalling in axon guidance in the Xenopus visual system. Development, 135, 333–342.
212. Su, J., Haner, C. V., Imbery, T. E., Brooks, J. M., Morhardt, D. R., Gorse, K., Fox, M. A. (2011). Reelin is required for classspecific retinogeniculate targeting. Journal of Neuroscience, 31, 575–586.
213. Sweeney, N. T., Tierney, H., & Feldheim, D. A. (2014). Tbr2 is required to generate a neural circuit mediating the pupillary light reflex. Journal of Neuroscience, 34, 5447–5453.
214. Syed, M. M., Lee, S., Zheng, J., & Zhou, Z. J. (2004). Stagedependent dynamics and modulation of spontaneous waves in the developing rabbit retina. Journal of Physiology, 560, 533–549.
215. Thakar, S., Chenaux, G., & Henkemeyer, M. (2011). Critical roles for EphB and ephrin-B bidirectional signalling in retinocollicular mapping. Nature Communications, 2, 431.
216. Thompson, H., Andrews, W., Parnavelas, J. G., & Erskine, L. (2009). Robo2 is required for Slit-mediated intraretinal axon guidance. Developmental Biology, 335, 418–426.
217. Thompson, H., Barker, D., Camand, O., & Erskine, L. (2006b). Slits contribute to the guidance of retinal ganglion cell axonsb in the mammalian optic tract. Developmental Biology, 296, 476–484.
218. Thompson, H., Camand, O., Barker, D., & Erskine, L. (2006a). Slit proteins regulate distinct aspects of retinal ganglion cell axon guidance within dorsal and ventral retina. Journal of Neuroscience, 26, 8082–8091.
219. Tian, N. M., Pratt, T., & Price, D. J. (2008). Foxg1 regulates retinal axon pathfinding by repressing an ipsilateral program in nasal retina and by causing optic chiasm cells to exert a net axonal growth-promoting activity. Development, 135, 4081–4089.
220. Torres, M., Gomez-Pardo, E., & Gruss, P. (1996). Pax2 contributes to inner ear patterning and optic nerve trajectory. Development, 122, 3381–3391.
221. Trousse, F., Marti, E., Gruss, P., Torres, M., & Bovolenta, P. (2001). Control of retinal ganglion cell axon growth: A new role for Sonic hedgehog. Development, 128, 3927–3936.
222. Tucker, R. P., Beckmann, J., Leachman, N. T., Scholer, J., & Chiquet-Ehrismann, R. (2011). Phylogenetic analysis of the teneurins: Conserved features and premetazoan ancestry. Molecular Biology and Evolution, 29, 1019–1029.
223. Tucker, R. P., & Chiquet-Ehrismann, R. (2006). Teneurins: A conserved family of transmembrane proteins involved in intercellular signaling during development. Developmental Biology, 290, 237–245.
224. Turner, D. L., Snyder, E. Y., & Cepko, C. L. (1990). Lineageindependent determination of cell type in the embryonic mouse retina. Neuron, 4, 833–845.
225. Upton, A. L., Salichon, N., Lebrand, C., Ravary, A., Blakely, R., Seif, I., Gaspar, P. (1999). Excess of serotonin (5-HT) alters the segregation of ispilateral and contralateral retinal projections in monoamine oxidase A knock-out mice: Possible role of 5-HT uptake in retinal ganglion cells during development. Journal of Neuroscience, 19, 7007–7024.
226. Van Hooser, S. D., & Nelson, S. B. (2006). The squirrel as a rodent model of the human visual system. Visual Neuroscience, 23, 765–778.
227. Victor, J. D., Apkarian, P., Hirsch, J., Conte, M. M., Packard, M., Relkin, N. R., Shapley, R. M. (2000). Visual function and brain organization in non-decussating retinal-fugal fibre syndrome. Cerebral Cortex, 10, 2–22.
228. von dem Hagen, E. A., Hoffmann, M. B., & Morland, A. B. (2008). Identifying human albinism: A comparison of VEP and fMRI. Investigative Ophthalmology & Visual Science, 49, 238–249.
229. Waid, D. K., & McLoon, S. C. (1995). Immediate differentiation of ganglion cells following mitosis in the developing retina. Neuron, 14, 117–124.
230. Waid, D. K., & McLoon, S. C. (1998). Ganglion cells influence the fate of dividing retinal cells in culture. Development, 125, 1059–1066.
231. Walz, A., Anderson, R. B., Irie, A., Chien, C. B., & Holt, C. E. (2002). Chondroitin sulfate disrupts axon pathfinding in the optic tract and alters growth cone dynamics. Journal of Neurobiology, 53, 330–342.
232. Walz, A., McFarlane, S., Brickman, Y. G., Nurcombe, V., Bartlett, P. F., & Holt, C. E. (1997). Essential role of heparan sulfates in axon navigation and targeting in the developing visual system. Development, 124, 2421–2430.
233. Wang, J., Chan, C. K., Taylor, J. S., & Chan, S. O. (2008). The growth-inhibitory protein Nogo is involved in midline routing of axons in the mouse optic chiasm. Journal of Neuroscience Research, 86, 2581–2590.
234. Wang, S. W., Kim, B. S., Ding, K., Wang, H., Sun, D., Johnson, R. L., Gan, L. (2001). Requirement for math5 in the development of retinal ganglion cells. Genes & Development, 15, 24–29.
235. Wang, Y., Dakubo, G. D., Thurig, S., Mazerolle, C. J., & Wallace, V. A. (2005). Retinal ganglion cell-derived sonic hedgehog locally controls proliferation and the timing of RGC development in the embryonic mouse retina. Development, 132, 5103–5113.
236. Webber, C. A., Hocking, J. C., Yong, V. W., Stange, C. L., & McFarlane, S. (2002). Metalloproteases and guidance of retinal axons in the developing visual system. Journal of Neuroscience, 22, 8091–8100.
237. Weiner, J. A., Koo, S. J., Nicolas, S., Fraboulet, S., Pfaff, S. L., Pourquie, O., Sanes, J. R. (2004). Axon fasciculation defects and retinal dysplasias in mice lacking the immunoglobulin superfamily adhesion molecule BEN/ALCAM/SC1. Molecular and Cellular Neuroscience, 27, 59–69.
238. Wetts, R., & Fraser, S. E. (1988). Multipotent precursors can give rise to all major cell types of the frog retina. Science, 239, 1142–1145.
239. White, L. E., Coppola, D. M., & Fitzpatrick, D. (2001). The contribution of sensory experience to the maturation of orientation selectivity in ferret visual cortex. Nature, 411, 1049–1052.
240. Williams, R. W., Hogan, D., & Garraghty, P. E. (1994). Target recognition and visual maps in the thalamus of achiasmatic dogs. Nature, 367, 637–639.
241. Williams, S. E., Grumet, M., Colman, D. R., Henkemeyer, M., Mason, C. A., & Sakurai, T. (2006). A role for Nr-CAM in the patterning of binocular visual pathways. Neuron, 50, 535–547.
242. Williams, S. E., Mann, F., Erskine, L., Sakurai, T., Wei, S., Rossi, D. J., Henkemeyer, M. (2003). Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm. Neuron, 39, 919–935.
243. Wizenmann, A., Brunet, I., Lam, J. S., Sonnier, L., Beurdeley, M., Zarbalis, K., Prochiantz, A. (2009). Extracellular Engrailed participates in the topographic guidance of retinal axons in vivo. Neuron, 64, 355–366.
244. Wong, G. K., Baudet, M. L., Norden, C., Leung, L., & Harris, W. A. (2012). Slit1b-Robo3 signaling and N-cadherin regulate apical process retraction in developing retinal ganglion cells. Journal of Neuroscience, 32, 223–228.
245. Wong, R. O., Meister, M., & Shatz, C. J. (1993). Transient period of correlated bursting activity during development of the mammalian retina. Neuron, 11, 923–938.
246. Wright, K. M., Lyon, K. A., Leung, H., Leahy, D. J., Ma, L., & Ginty, D. D. (2012). Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron, 76, 931–944.
247. Xiang, M., Zhou, L., Macke, J. P., Yoshioka, T., Hendry, S. H., Eddy, R. L., Nathans, J. (1995). The Brn-3 family of POUdomain factors: Primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons. Journal of Neuroscience, 15, 4762–4785.
248. Xu, H., Leinwand, S. G., Dell, A. L., Fried-Cassorla, E., & Raper, J. A. (2010). The calmodulin-stimulated adenylate cyclase ADCY8 sets the sensitivity of zebrafish retinal axons to midline repellents and is required for normal midline crossing. Journal of Neuroscience, 30, 7423–7433.
249. Xu, H. P., Furman, M., Mineur, Y. S., Chen, H., King, S. L., Zenisek, D., Crair, M. C. (2011). An instructive role for patterned spontaneous retinal activity in mouse visual map development. Neuron, 70, 1115–1127.
250. Yang, Z., Ding, K., Pan, L., Deng, M., & Gan, L. (2003). Math5 determines the competence state of retinal ganglion cell progenitors. Developmental Biology, 264, 240–254.
251. Yoo, S., Kim, Y., Noh, H., Lee, H., Park, E., & Park, S. (2011). Endocytosis of EphA receptors is essential for the proper development of the retinocollicular topographic map. EMBO Journal, 30, 1593–1607.
252. Young, R. W. (1985). Cell differentiation in the retina of the mouse. The Anatomical Record, 212, 199–205.
253. Young, T. R., Bourke, M., Zhou, X., Oohashi, T., Sawatari, A., Fassler, R., Leamey, C. A. (2013). Ten-m2 is required for the generation of binocular visual circuits. Journal of Neuroscience, 33, 12490–12509.
254. Zhang, F., Lu, C., Severin, C., & Sretavan, D. W. (2000). GAP- 43 mediates retinal axon interaction with lateral diencephalon cells during optic tract formation. Development, 127, 969–980.
255. Zhang, J., Jin, Z., & Bao, Z. Z. (2004). Disruption of gradient expression of Zic3 resulted in abnormal intra-retinal axon projection. Development, 131, 1553–1562.
256. Zhang, X. M., & Yang, X. J. (2001). Regulation of retinal ganglion cell production by Sonic hedgehog. Development, 128, 943–957.
257. Zheng, J. J., Lee, S., & Zhou, Z. J. (2004). A developmental switch in the excitability and function of the starburst network in the mammalian retina. Neuron, 44, 851–864.
258. Zolessi, F. R., Poggi, L., Wilkinson, C. J., Chien, C. B., & Harris, W. A. (2006). Polarization and orientation of retinal ganglion cells in vivo. Neural Development, 1, 2.