Odorant receptor-derived cAMP signals direct axonal targeting

Science

Volumn 314, Issue 5799, 2006, Pages 657-661

  Imai, Takeshi ^a,b   Suzuki, Misao ^c   Sakano, Hitoshi ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; CELLS; MOLECULAR BIOLOGY; SIGNAL PROCESSING;

ANTERIOR-POSTERIOR AXIS; ODORANT RECEPTORS (OR); OLFACTORY SENSORY NEURONS (OSN); STIMULATORY G PROTEIN;

PROTEINS;

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; ODORANT RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG;

ENZYME ACTIVITY; MAMMAL; OLFACTORY CUE; PROTEIN; SENSORY SYSTEM;

ANIMAL CELL; ARTICLE; GENE EXPRESSION REGULATION; GENETIC MANIPULATION; NERVE FIBER TRANSPORT; NONHUMAN; OLFACTORY BULB; OLFACTORY SYSTEM; PRIORITY JOURNAL; SENSORY NERVE CELL; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; AXONS; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEUROPILIN-1; OLFACTORY BULB; OLFACTORY RECEPTOR NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, WISTAR; RECEPTORS, ODORANT; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

MAMMALIA;

EID: 33750431061     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1131794     Document Type: Article

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28. This work was supported by the CREST Program of the Japan Science and Technology Agency and by grants from Mitsubishi Foundation, Japan Society for the Promotion of Science (JSPS), and the Ministry of Education, Culture and Science of Japan. T.I. was supported by a predoctoral fellowship of JSPS. We thank A. Miyawaki, R. Sprengel, S. McKnight, and M. Mishina for cDNA clones and T. Yamamori, H. Matsunami, and members of our laboratory for valuable comments.