EphB forward signaling controls directional branch extension and arborization required for dorsal-ventral retinotopic mapping

Neuron

Volumn 35, Issue 3, 2002, Pages 475-487

  Hindges, Robert ^a   McLaughlin, Todd ^a   Genoud, Nicolas ^a   Henkemeyer, Mark ^b   O'Leary, Dennis D M ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPHRIN; EPHRIN B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DISRUPTION; CONTROLLED STUDY; GENE MAPPING; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RETINA CELL; SIGNAL TRANSDUCTION; SUPERIOR COLLICULUS;

EID: 0036685537     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(02)00799-7     Document Type: Article

References (50)

1. Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina
2. In vitro experiments on axon guidance demonstrating an anterior-posterior gradient on the tectum
3. Position-dependent properties of retinal axons and their growth cones
4. Graded and lamina-specific distributions of ligands of EphB receptor tyrosine kinases in the developing retinotectal system
5. Topographic mapping from the retina to the midbrain is controlled by relative but not absolute levels of EphA receptor signaling
6. Tyrosine phosphorylation of transmembrane ligands for Eph receptors
7. Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map
8. Expression and tyrosine phosphorylation of Eph receptors suggest multiple mechanisms in patterning of the visual system
9. EphB2 guides axons at the midline and is necessary for normal vestibular function
10. In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases
11. A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system
12. Topographic guidance labels in a sensory projection to the forebrain
13. Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping
14. Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system
15. Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis
16. Directional cues for growing axons forming the retinotectal projection
17. A gradient of adhesive specificity in developing avian retina
18. Nuk controls pathfinding of commissural axons in the mammalian central nervous system
19. Polarized expression of the receptor protein tyrosine kinase Cek5 in the developing avian visual system
20. Reciprocal expression of the Eph receptor Cek5 and its ligand(s) in the early retina
21. Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands
22. Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells
23. Modulation of EphA receptor function by coexpressed ephrinA ligands on retinal ganglion cell axons
24. Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through αvβ3 and α5β1 integrins
25. Tbx5 and the retinotectum projection
26. Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo
27. Ephrin-B3 is the midline barrier that prevents corticospinal axons from recrossing, allowing for unilateral motor control
28. Biochemical investigations of retinotectal adhesivity
29. The first retinal axon growth in the mouse optic chiasm: Axon patterning and the cellular environment
30. Eph family receptors and their ligands distribute in opposing gradients in the developing mouse retina
31. Shared and distinct functions of RAGS and ELF-1 in guiding retinal axons
32. The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye
33. Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo
34. Inaccuracies in initial growth and arborization of chick retinotectal axons followed by course corrections and axon remodeling to develop topographic order
35. Topographic targeting errors in the retinocollicular projection and their elimination by selective ganglion cell death
36. Mapping sights and smells in the brain: Distinct mechanisms to achieve a common goal
37. Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation
38. Control of topographic retinal axon branching by inhibitory membrane-bound molecules
39. Ventroptin: A BMP-4 antagonist expressed in a double gradient pattern in the retina
40. Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map
41. Responses of retinal axons in vivo and in vitro to position-encoding molecules in the embryonic superior colliculus
42. Influence of position along the medial-lateral axis of the superior colliculus on the topographic targeting and survival of retinal axons
43. Development of topographic order in the mammalian retinocollicular projection
44. Signal transduction underlying growth cone guidance by diffusible factors
45. Chemoaffinity in the orderly growth of nerve fiber patterns and connections
46. Nck recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase
47. Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro
48. Eph family transmembrane ligands can mediate repulsive guidance of trunk neural crest migration and motor axon outgrowth
49. Topographic specific axon branching controlled by ephrin-As is the critical event in retinotectal map development
50. Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline