Analysis of the oxidative damage of DNA, RNA, and their metabolites induced by hyperglycemia and related nephropathy in Sprague Dawley rats

Free Radical Research

Volumn 49, Issue 10, 2015, Pages 1199-1209

  Wang, Wan Xia ^a,b   Luo, Shun Bin ^c   Xia, Meng Ming ^c   Mao, Yong Hui ^d   Zhou, Xiao Yang ^b   Jiang, Ping ^b   Jiang, Hai Yan ^c   Dai, Da Peng ^b   Li, Chuan Bao ^d   Hu, Guo Xin ^c   Cai, Jian Ping ^b  

^a GRADUATE SCHOOL OF PEKING UNION MEDICAL COLLEGE   (China)

^b BEIJING HOSPITAL   (China)

^c WENZHOU MEDICAL UNIVERSITY   (China)

^d BEIJING HOSPITAL   (China)

Author keywords

8 oxo 7 8 dihydroguanosin; biomarker; guanosine; hyperglycemia; ID LC MS MS

Indexed keywords

DEOXYGUANOSINE DERIVATIVE; DNA; GUANOSINE DERIVATIVE; RNA; 8-HYDROXYGUANINE; BIOLOGICAL MARKER; GUANINE; STREPTOZOCIN;

ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DNA DAMAGE; GLUCOSE BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERGLYCEMIA; ISOTOPE DILUTION ASSAY; KIDNEY DISEASE; KIDNEY HYPERTROPHY; METABOLITE; NONHUMAN; OXIDATIVE STRESS; QUADRUPOLE MASS SPECTROMETRY; RAT; TANDEM MASS SPECTROMETRY; URINALYSIS; ANALOGS AND DERIVATIVES; ANIMAL; COMPARATIVE STUDY; EXPERIMENTAL DIABETES MELLITUS; GENETICS; MASS SPECTROMETRY; METABOLISM; RANDOMIZATION; SPRAGUE DAWLEY RAT; TIME FACTOR;

RATTUS;

ANIMALS; BIOMARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DNA; DNA DAMAGE; GUANINE; HYPERGLYCEMIA; MASS SPECTROMETRY; OXIDATIVE STRESS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RNA; STREPTOZOCIN; TIME FACTORS;

EID: 84940045418     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2015.1033416     Document Type: Article

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