Not All Biofluids Are Created Equal: Chewing over Salivary Diagnostics and the Epigenome

Clinical Therapeutics

Volumn 37, Issue 3, 2015, Pages 529-539

  Wren, Michael E ^a,b   Shirtcliff, Elizabeth A ^c   Drury, Stacy S ^a,b  

^a TULANE UNIVERSITY   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c IOWA STATE UNIVERSITY   (United States)

Author keywords

biomarker; DNA methylation; epige nome; salivary diagnostics; salivary transcriptome; telomere length

Indexed keywords

BIOLOGICAL MARKER; MICRORNA; PROTEOME;

CHEMISTRY; DIAGNOSIS; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION PROFILING; GENOME; HUMAN; MASTICATION; MICROBIOLOGY; MICROFLORA; PROCEDURES; SALIVA; TELOMERE;

BIOMARKERS; DIAGNOSIS; DNA METHYLATION; EPIGENOMICS; GENE EXPRESSION PROFILING; GENOME; HUMANS; MASTICATION; MICROBIOTA; MICRORNAS; PROTEOME; SALIVA; TELOMERE;

EID: 84939995767     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2015.02.022     Document Type: Article

References (74)

1. T.K. Fabian, P. Fejerdy, and P. Csermely Salivary genomics, transcriptomics and proteomics: The emerging concept of the oral ecosystem and their use in the early diagnosis of cancer and other diseases Curr Genomics 9 2008 11 21
2. R. Pramanik Effects of the UK Biobank collection protocol on potential biomarkers in saliva Int J Epidemiol 41 2012 1786 1797
3. N. Spielmann The human salivary RNA transcriptome revealed by massively parallel sequencing Clin Chem 58 2012 1314 1321
4. F.M. Amado, R.P. Ferreira, and R. Vitorino One decade of salivary proteomics: current approaches and outstanding challenges Clin Biochem 46 2013 506 517
5. N.J. Park Characterization of RNA in saliva Clin Chem 52 2006 988 994
6. N. Spielmann, and D.T. Wong Saliva: diagnostics and therapeutic perspectives Oral Dis 17 2011 345 354
7. A. Vidovic Determination of leucocyte subsets in human saliva by flow cytometry Arch Oral Biol 57 2012 577 583
8. S.P. Humphrey, and R.T. Williamson A review of saliva: normal composition, flow, and function J Prosthet Dent 85 2001 162 169
9. J.M. Yoshizawa Salivary biomarkers: toward future clinical and diagnostic utilities Clin Microbiol Rev 26 2013 781 791
10. D. Malamud, and I.R. Rodriguez-Chavez Saliva as a diagnostic fluid Dent Clin North Am 55 2011 159 178
11. K.P. Theall Early hits and long-term consequences: tracking the lasting impact of prenatal smoke exposure on telomere length in children Am J Public Health 103 suppl 1 2013 S133 S135
12. K.P. Theall Neighborhood disorder and telomeres: connecting childrens exposure to community level stress and cellular response Soc Sci Med 85 2013 50 58
13. C. Mitchell Social disadvantage, genetic sensitivity, and childrens telomere length Proc Natl Acad Sci U S A 111 2014 5944 5949
14. M.J. Meaney, M. Szyf, and J.R. Seckl Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health Trends Mol Med 13 2007 269 277
15. J.A. Loo Comparative human salivary and plasma proteomes J Dent Res 89 2010 1016 1023
16. R.F. Vining, R.A. McGinley, and R.G. Symons Hormones in saliva: mode of entry and consequent implications for clinical interpretation Clin Chem 29 1983 1752 1756
17. T.V. Hansen Collection of blood, saliva, and buccal cell samples in a pilot study on the Danish nurse cohort: comparison of the response rate and quality of genomic DNA Cancer Epidemiol Biomarkers Prev 16 2007 2072 2076
18. D.A. Granger Incorporating Salivary Biomarkers Into Nursing Research: An Overview and Review of Best Practices Biol Res Nurs 14 2012 347 356
19. D.A. Granger Integration of salivary biomarkers into developmental and behaviorally-oriented research: Problems and solutions for collecting specimens Physiol Behav 92 2007 583 590
20. D.A. Granger Focus on Methodology: Salivary bioscience and research on adolescence: An integrated perspective J Adolesc 35 2012 1081 1095
21. P.D. Slowey C. Streckfus, Saliva Collection Devices and Diagnostic Platforms, in Advances in Salivary Diagnostics 2015 Springer-Verlag Berlin Heidelberg
22. P.D. Slowey Commercial saliva collections tools J Calif Dent Assoc 41 102-5 2013 97 99
23. V. de Almeida Pdel Saliva composition and functions: a comprehensive review J Contemp Dent Pract 9 2008 72 80
24. M. Navazesh, and S.K.S. Kumar Measuring salivary flow - Challenges and opportunities J Am Dent Assoc 139 2008 35S 40S
25. J.G. Lewis Steroid analysis in saliva: an overview Clin Biochem Rev 27 2006 139 146
26. E.A. Shirtcliff Use of salivary biomarkers in biobehavioral research: cotton-based sample collection methods can interfere with salivary immunoassay results Psychoneuroendocrinology 26 2001 165 173
27. M. Navazesh Methods for collecting saliva Ann N Y Acad Sci 694 1993 72 77
28. P.D. Tryphonopoulos, N. Letourneau, and R. Azar Approaches to salivary cortisol collection and analysis in infants Biol Res Nurs 16 2014 398 408
29. Human Microbiome Project, C. A framework for human microbiome research Nature 486 2012 215 221
30. M.A. Nadkarni Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set Microbiology-Sgm 148 2002 257 266
31. T. Chen The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information Database (Oxford) 2010 baq013
32. W.H. Yan Systematic comparison of the human saliva and plasma proteomes Proteomics Clin Appl 3 2009 116 134
33. E. Zaura Defining the healthy "core microbiome" of oral microbial communities BMC Microbiol 9 2009 259
34. T. Pfaffe Diagnostic potential of saliva: current state and future applications Clin Chem 57 2011 675 687
35. S.S. Drury Growing up or growing old? Cellular aging linked with testosterone reactivity to stress in youth Am J Med Sci 348 2014 92 100
36. S. Chiappin Saliva specimen: a new laboratory tool for diagnostic and basic investigation Clin Chim Acta 383 2007 30 40
37. W.S. Gozansky Salivary cortisol determined by enzyme immunoassay is preferable to serum total cortisol for assessment of dynamic hypothalamic - pituitary - adrenal axis activity Clin Endocrinol (Oxf) 63 2005 336 341
38. K. Marceau, L.D. Dorn, and E.J. Susman Stress and puberty-related hormone reactivity, negative emotionality, and parent - adolescent relationships Psychoneuroendocrinology 37 2012 1286 1298
39. K. Marceau Within-adolescent coupled changes in cortisol with DHEA and testosterone in response to three stressors during adolescence Psychoneuroendocrinology 41 2014 33 45
40. J.Y. Liu A Study of the Influence of Sex on Genome Wide Methylation Plos One 2010 5
41. Z. Nemoda Assessing genetic polymorphisms using DNA extracted from cells present in saliva samples BMC Med Res Methodol 11 2011 170
42. T.M. Thompson Comparison of whole-genome DNA methylation patterns in whole blood, saliva, and lymphoblastoid cell lines Behav Genet 43 2013 168 176
43. G. Endler Genetic fingerprinting in mouthwashes of patients after allogeneic bone marrow transplantation Bone Marrow Transplant 24 1999 95 98
44. C. Thiede Buccal swabs but not mouthwash samples can be used to obtain pretransplant DNA fingerprints from recipients of allogeneic bone marrow transplants Bone Marrow Transplant 25 2000 575 577
45. N.J. Bonne, and D.T. Wong Salivary biomarker development using genomic, proteomic and metabolomic approaches Genome Med 4 2012 82
46. C. Sapienza DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy Epigenetics 6 2011 20 28
47. T.I. Jones Identifying diagnostic DNA methylation profiles for facioscapulohumeral muscular dystrophy in blood and saliva using bisulfite sequencing Clin Epigenetics 6 2014 23
48. N. Weder Child abuse, depression, and methylation in genes involved with stress, neural plasticity, and brain circuitry J Am Acad Child Adolesc Psychiatry 53 e5 2014 417 424
49. A.K. Smith DNA extracted from saliva for methylation studies of psychiatric traits: Evidence tissue specificity and relatedness to brain Am J Med Genet B Neuropsychiatr Genet 9999B 2014 1 9
50. Y.S. Nikolova Beyond genotype: serotonin transporter epigenetic modification predicts human brain function Nat Neurosci 17 2014 1153 1155
51. H.M. Abdolmaleky DNA hypermethylation of serotonin transporter gene promoter in drug naive patients with schizophrenia Schizophr Res 152 2014 373 380
52. M. Ghadirivasfi Hypomethylation of the serotonin receptor type-2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder Am J Med Genet B Neuropsychiatr Genet 156B 2011 536 545
53. S. Nohesara DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder J Psychiatr Res 45 11 2011 1432 1438
54. B.Z. Yang Child abuse and epigenetic mechanisms of disease risk Am J Prev Med 44 2013 101 107
55. R.M. Cawthon Telomere length measurement by a novel monochrome multiplex quantitative PCR method Nucleic Acids Res 37 2009 e21
56. X. Chen Smoking and perceived stress in relation to short salivary telomere length among caregivers of children with disabilities Stress 2014 1 9
57. N.J. Park Characterization of salivary RNA by cDNA library analysis Arch Oral Biol 52 2007 30 35
58. C. Lau Role of pancreatic cancer-derived exosomes in salivary biomarker development J Biol Chem 288 2013 26888 26897
59. A. Segal, and D.T. Wong Salivary diagnostics: enhancing disease detection and making medicine better Eur J Dent Educ 12 suppl 1 2008 22 29
60. Y. Li RNA Profiling of Cell-free Saliva Using Microarray Technology J Dent Res 83 2004 199 203
61. H.J. Eichel, N. Conger, and W.S. Chernick Acid and Alkaline Ribonucleases of Human Parotid, Submaxillary, and Whole Saliva Arch Biochem Biophys 107 1964 197 208
62. S.V. Kumar, G.J. Hurteau, and S.D. Spivack Validity of messenger RNA expression analyses of human saliva Clin Cancer Res 12 2006 5033 5039
63. B.G. Zimmermann, N.J. Park, and D.T. Wong Genomic targets in saliva Ann N Y Acad Sci 1098 2007 184 191
64. C.S. Lau, and D.T. Wong Breast cancer exosome-like microvesicles and salivary gland cells interplay alters salivary gland cell-derived exosome-like microvesicles in vitro PLoS One 7 2012 e33037
65. K. Gao Systemic Disease-Induced Salivary Biomarker Profiles in Mouse Models of Melanoma and Non-Small Cell Lung Cancer Plos One 2009 4
66. N.J. Park Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection Clin Cancer Res 15 2009 5473 5477
67. E.K. Hanson, H. Lubenow, and J. Ballantyne Identification of forensically relevant body fluids using a panel of differentially expressed microRNAs Anal Biochem 387 2009 303 314
68. D. Zubakov MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation Int J Legal Med 124 2010 217 226
69. J.A. Weber The microRNA spectrum in 12 body fluids Clin Chem 56 2010 1733 1741
70. A. Gallo The majority of microRNAs detectable in serum and saliva is concentrated in exosomes PLoS One 7 2012 e30679
71. A. Michael Exosomes from human saliva as a source of microRNA biomarkers Oral Dis 16 2010 34 38
72. C. Courts, and B. Madea Specific micro-RNA signatures for the detection of saliva and blood in forensic body-fluid identification J Forensic Sci 56 2011 1464 1470
73. A. Formosa Salivary miRNAome profiling uncovers epithelial and proliferative miRNAs with differential expression across dentition stages Cell Cycle 10 2011 3359 3368
74. J.Y. Ai, B. Smith, and D.T. Wong Bioinformatics advances in saliva diagnostics Int J Oral Sci 4 2012 85 87