Incorporating Salivary Biomarkers Into Nursing Research: An Overview and Review of Best Practices

Biological Research for Nursing

Volumn 14, Issue 4, 2012, Pages 347-356

  Granger, Douglas A ^a,b,c   Johnson, Sara B ^b,c   Szanton, Sarah L ^a   Out, Dorothée ^a,d   Schumann, Lynette Lau ^e  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d LEIDEN UNIVERSITY   (Netherlands)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

best practices; nursing research; salivary biomarkers

Indexed keywords

BIOLOGICAL MARKER;

ARTICLE; CHEMISTRY; HUMAN; LABORATORY DIAGNOSIS; NURSING RESEARCH; QUALITY CONTROL; SALIVA;

BENCHMARKING; BIOLOGICAL MARKERS; HUMANS; NURSING RESEARCH; SALIVA; SPECIMEN HANDLING;

EID: 84866640426     PISSN: 10998004     EISSN: 15524175     Source Type: Journal    
DOI: 10.1177/1099800412443892     Document Type: Article

References (71)

1. Anhøj J.,Møldrup C.Feasibility of collecting diary data from asthma patients through mobile phones and SMS (short message service): Response rate analysis and focus group evaluation from a pilot study.Journal of Medical Internet Research. 2004;6:e42.
2. Arendorf T. M.,Bredekamp B.,Cloete C. A.,Sauer G.Oral manifestations of HIV infection in 600 South African patients.Journal of Oral Pathology and Medicine. 1998;27:176-179.
3. Beltzer E. K.,Fortunato C. K.,Guaderrama M. M.,Peckins M. K.,Garramone B. M.,Granger D. A.Salivary flow on alpha-amylase: Collection technique, duration, and oral fluid type.Physiology and Behavior. 2010;101:289-296.
4. Berkman E. T.,Falk E. B.,Lieberman M. D.In the trenches of real-world self-control: Neural correlates of breaking the link between craving and smoking.Psychological Science. 2011;22:498-506.
5. Booth A.,Johnson D. R.,Granger D. A.,Crouter A. C.,McHale S.Testosterone and child and adolescent adjustment: The moderating role of parent-child relationships.Developmental Psychology. 2003;39:85-98.
6. Brandtzaeg P.Do salivary antibodies reliably reflect both mucosal and systemic immunity?.Annals of the New York Academy of Science. 2007;1098:288-311.
7. Bryk A. S.,Raudenbush S. W.Hierarchical linear models. Newbury Park, CA: SAGE; 1992:.
8. Butz A. M.,Halterman J. S.,Bellin M.,Tsoukleris M.,Donithan M.,Kub J.,Bollinger M. E.Factors associated with second-hand smoke exposure in young inner-city children with asthma.Journal of Asthma. 2011;48:449-457.
9. Carter C. S.,Pournajafi-Nazarloo H.,Kramer K. M.,Ziegler T. E.,White-Traut R,Bello D.,Schwertz D.Oxytocin: Behavioral associations and potential as a salivary biomarker.Annals of the New York Academy of Science. 2007;1098:312-322.
10. Chard T.1990). An introduction to radioimmunoassay and related techniques (4th ed.). Amsterdam, Netherlands: Elsevier.Amsterdam, Netherlands: Elsevier; 1990:.
11. Clingerman E. M.,Brown A.Stress in migrant farmworkers during premigration.Biological Research for Nursing. 2012;14:27-37.
12. Cone E. J.,Huestis M. A.Interpretation of oral fluid tests for drugs of abuse.Annals of the New York Academy of Science. 2007;1098:51-103.
13. Dabbs J. M.Salivary testosterone measurements: Collecting, storing, and mailing saliva samples.Physiology and Behavior. 1991;49:815-817.
14. Dawidson I.,Blom M.,Lundeberg T.,Theodorsson E.,Angmar-Mansson B.Neuropeptides in the saliva of healthy subjects.Life Sciences. 1997;60:269-278.
15. De Geus E. J. C.,Kupper N.,Boomsma D. I.,Snieder H.Bivariate genetic modeling of cardiovascular stress reactivity: Does stress uncover genetic variance?.Psychosomatic Medicine. 2007;69:356-364.
16. Gill J. M.,Szanton S.,Taylor T. J.,Page G. G.,Campbell J. C.Medical conditions and symptoms associated with posttraumatric stress disorders in low-income urban women.Journal of Women's Health. 2009;18:261-267.
17. Gordis E. B.,Granger D. A.,Susman E. J.,Trickett P. K.Salivary alpha amylase-cortisol asymmetry in maltreated youth.Hormones and Behavior. 2008;53:96-1003.
18. Granger D. A.,Cicchetti D.,Rogosch F. A.,Hibel L. C.,Teisl M.,Flores E.Blood contamination in children's saliva: Prevalence, stability, and impact on the measurement of salivary cortisol, testosterone, and dehydroepiandrosterone.Psychoneuroendocrinology. 2007;32:724-733.
19. Granger D. A.,Hibel L. C.,Fortunato C. K.,Kapelewski C. H.Medication effects on salivary cortisol: Tactics and strategy to minimize impact in behavioral and developmental science.Psychoneuroendocrinology. 2009;34:1437-1448.
20. Granger D. A.,Kivlighan K. T.,El-Sheikh M.,Gordis E. B.,Stroud L. R.Salivary alpha-amylase in biobehavioral research: Recent developments and applications.Annals of the New York Academy of Science. 2007;1098:122-144.
21. Granger D. A.,Kivlighan K. T.,Fortunato C.,Harmon A. G.,Hibel L. C.,Schwartz E. B.,Whembolua G. L.Integration of salivary biomarkers into developmental and behaviorally-oriented research: Problems and solutions for collecting specimens.Physiology and Behavior. 2007;92:583-590.
22. Granger D. A.,Schwartz E. B.,Booth A.,Curran M.,Zakaria D.Assessing dehydroepiandrosterone in saliva: A simple radioimmunoassay for use in studies of children, adolescents and adults.Psychoneuroendocrinology. 1999;24:567-579.
23. Granger D. A.,Shirtcliff E. A.,Booth A.,Kivlighan K. T.,Schwartz E. B.The "trouble" with salivary testosterone.Psychoneuroendocrinology. 2004;29:1229-1240.
24. Groschl M.,Rauh M.Influence of commercial collection devices for saliva on the reliability of salivary steroids analysis.Steroids. 2006;71:1097-1100.
25. Gunnar M. R.,Mangelsdorf S.,Larson M.,Hertsgaard L.Attachment, temperament, and adrenocortical activity in infancy: A study of psychoendocrine regulation.Developmental Psychology. 1989;3:355-363.
26. Gunnar M. R.,Vasquez D.Low cortisol and a flattening of the expected daytime rhythm: Potential indices of risk in human development.Development and Psychopathology. 2001;13:515-538.
27. Haeckel R.,Bucklitsch I.Procedures for saliva sampling.Journal of Clinical Chemistry and Biochemistry. 1987;25:199-204.
28. Harmon A. G.,Hibel L. C.,Rumyansteva O.,Granger D. A.Measuring salivary cortisol in studies of child development: Watch out--What goes in may not come out of saliva collection devices.Developmental Psychobiology. 2007;49:495-500.
29. Harmon A.G.,Towe N. R.,Fortunato C. K.,Granger D. A.Differences in saliva collection location and disparities in baseline and diurnal rhythms of alpha-amylase: A preliminary note of caution.Hormones and Behavior. 2008;54:592-596.
30. Hellhammer J.,Fries E.,Schweusthal O. W.,Schlotz W.,Stone A. A.,Hagemann D.Several daily measurements are necessary to reliably assess the cortisol rise after awakening: State- and trait components.Psychoneuroendocrinology. 2007;32:80-86.
31. Hodgson N.,Freedman V. A.,Granger D. A.,Erno A.Biobehavioral correlates of relocation in the frail elderly: Salivary cortisol, affect, and cognitive function.Journal of the American Geriatric Society. 2004;52:1856-1862.
32. Hox J.Multilevel analysis: Techniques and applications. London, England: Lawrence Erlbaum; 2002:.
33. Hu S.,Loo J. A.,Wong D. T.Human saliva proteome analysis.Annals of the New York Academy of Science. 2007;1098:323-329.
34. Kivlighan K. T.,Granger D. A.,Schwartz E. B.,Nelson V.,Curran M.,Shirtcliff E. A.Quantifying blood leakage into the oral mucosa and its effects on the measurement of cortisol, dehydroepiandrosterone, and testosterone in saliva.Hormones and Behavior. 2004;46:39-46.
35. Kreft I.,De Leeuw J.Introducing multilevel modeling. London, England: SAGE; 1998:.
36. Krishna S.,Boren S. A.,Balas E. A.Healthcare via cell phones: A systematic review.Telemedicine and e-Health. 2009;15:231-240.
37. Kudielka M. B.,Schommer C. N.,Hellhammer H. D.,Kirschbaum C.Acute HPA axis responses, heart rate, and mood changes to psychosocial stress (TSST) in humans at different times of day.Psychoneuroendocrinology. 2004;29:983-992.
38. Kugler J.,Hess M.,Haake D.Secretion of salivary immunoglobulin A in relation to age, saliva flow, mood states, secretion of albumin, cortisol, and catecholamines in saliva.Journal of Clinical Immunology. 1992;12:45-49.
39. Maffini M. V.,Rubin B. S.,Sonnenschein C.,Soto A. M.Endocrine disruptors and reproductive health: The case of bisphenol-A.Molecular and Cellular Endocrinology. 2006;254:179-186.
40. Magnano C. L.,Diamond E. J.,Gardner J. M.Use of salivary cortisol measurements in young infants: A note of caution.Child Development. 1989;60:1099-1101.
41. Malamud D.,Niedbala R. S.Introduction.Annals of the New York Academy of Sciences. 2007;1098:xiv-xv.
42. Malamud D.,Tabak L.Saliva as a diagnostic fluid.Annals of the New York Academy of Sciences. 1993;694:216-233.
43. McArdle J. J.,Bell R. Q.Modeling longitudinal and multiple-group data: Practical issues, applied approaches, and specific examples. Little T. D.Schnabel K. U.Baumert J., ed. Hillsdale, NJ: Lawrence Erlbaum; 2000:69-107.
44. McArdle J. J.,Nesselroade J.Life-span developmental psychology. Cohen S. H.Reese H. W., ed. Hillsdale, NJ: Lawrence Erlbaum; 1994:223-267.
45. Melnick R.,Lucier G.,Wolfe M.,Hall R.,Stancel G.,Prins G.,Kohn M.Summary of the National Toxicology Program's report of the endocrine disruptors low-dose peer review.Environmental Health Perspectives. 2002;110:427-431.
46. Nater U. M.,Rohleder N.,Schlotz W.,Ehlert U.,Kirschbaum C.Determinants of the diurnal course of salivary alpha-amylase.Psychoneuroendocrinology. 2007;32:392-401.
47. Nelson R. J.An introduction to behavioral endocrinology. Sunderland, MA: Sinauer Associates; 2005:.
48. Nemoda Z.,Horvat-Gordon M.,Fortunato C. K.,Beltzer E. K.,Scholl J. L.,Granger D. A.Assessing genetic polymorphisms using DNA extracted from cells present in saliva samples.BMC Medical Research Methodology, 11, 170. 2011;:.
49. Neu M.,Laudenslager M. L.,Robinson J.Coregulation in salivary cortisol during maternal holding of premature infants.Biological Research for Nursing. 2009;10:226-240.
50. Nieuw Amerongen A. V.,Ligtenberg A. J. M.,Veerman E. C. I.Implications for diagnostics in the biochemistry and physiology of saliva.Annals of the New York Academy of Science. 2007;1098:1-6.
51. O'Donnell K.,Kammerer M.,O'Reilly R.,Taylor A.,Glover V.Salivary alpha-amylase stability, diurnal profile and lack of response to the cold hand test in young women.Stress. 2009;12:549-554.
52. Out D.,Bakermans-Kranenburg M. J.,Granger D. A.,Cobbaert C. M.,Van IJzendoorn M. H.State and trait variance in salivary α-amylase: A behavioral genetic study.Biological Psychology. 2011;88:147-154.
53. Paster B. J.,Boches S. K.,Galvin J. L.,Ericson R. E.,Lau C. N.,Levanos V. A.,Dewhirst F. E.Bacterial diversity in human subgingival plaque.Journal of Bacteriology. 2001;183:3770-3783.
54. Pruessner J.,Kirschbaum C.,Meinlschmid G.,Hellhammer D. H.Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change.Psychoneuroendocrinology. 2003;28:916-931.
55. Raff H.,Homar P. J.,Skoner D. P.New enzyme immunoassay for salivary cortisol.Clinical Chemistry. 2003;49:203-204.
56. Rees T. D.Oral effects of drug abuse.Critical Reviews in Oral Biology and Medicine. 1992;3:163-184.
57. Reibel J.Tobacco and oral diseases. Update on the evidence, with recommendations.Medical Principles and Practice. 2003;12:22-32.
58. Santavirta N.,Konttinen Y. T.,Tornwall J.,Segerberg M.,Santavirta S.,Matucci-Cerinic M,Bjorvell H.Neuropeptides of the autonomic nervous system in Sjogren's syndrome.Annals of Rheumatoid Disease. 1997;56:737-740.
59. Scannapieco F. A.,Papandonatos G. D.,Dunford R. G.Associations between oral conditions and respiratory disease in a national sample survey population.Annals of Periodontology. 1998;3:251-256.
60. Schwartz E. B.,Granger D. A.,Susman E. J.,Gunnar M. R.,Laird B.Assessing salivary cortisol in studies of child development.Child Development. 1998;69:1503-1513.
61. Shirtcliff E. A.,Granger D.A.,Schwartz E. B.,Curran M. J.Use of salivary biomarkers in biobehavioral research: Cotton based sample collection methods can interfere with salivary immunoassay results.Psychoneuroendocrinology. 2001;26:165-173.
62. Smyth J. M.,Ockenfels M. C.,Gorin A. A.,Cately D.,Porter L. S.,Kirschbaum C.,Stone A. A.Individual differences in the diurnal cycle of cortisol.Psychoneuroendocrinology. 1997;22:89-105.
63. Sreebny L. M.,Schwartz S. S.A reference guide to drugs and dry mouth-2nd edition.Gerodontology. 1997;14:33-47.
64. Stone A. A.,Broderick J. E.,Schwartz J. E.,Shiffman S.,Litcher-Kelly L.,Calvanese P.Intensive momentary reporting of pain with an electronic diary: Reactivity, compliance, and patient satisfaction.Pain. 2003;104:343-351.
65. Szanton S. L.,Gill J. M.Facilitating resilience using a society-to-cells framework: A theory of nursing essentials applied to research and practice.Advances in Nursing Science. 2010;33:329-343.
66. Tabak L. A.Point-of-care diagnostics enter the mouth.Annals of the New York Academy of Science. 2007;1098:7-14.
67. Twisk J. W. R.Applied multilevel analysis: A practical guide. Cambridge, UK: Cambridge University Press; 2006:.
68. Oral Health in America: A Report of the Surgeon General. Rockville, MD: U.S. Department of Health and Human Services, National Institute of Dental and Craniofacial Research, National Institutes of Health; 2000:.
69. Veerman E. C. I.,Van Den Keijbus P. A. M.,Vissink A.,Nieuw Amerongen A. V.Human glandular saliva: Their separate collection and analysis.European Journal of Oral Science. 1996;104:346-352.
70. Woods D. L.,Mentes J. C.Spit: Saliva in nursing research, uses and methodological considerations in older adults.Biological Research for Nursing. 2011;13:320-327.
71. Zimmerman B. G.,Park N. J.,Wong D. T.Genomic targets in saliva.Annals of the New York Academy of Science. 2007;1098:184-191.