GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ

Cellular Signalling

Volumn 27, Issue 6, 2015, Pages 1237-1245

  Li, Zongwei ^a   Wang, Yingying ^a   Newton, Ian P ^c   Zhang, Lichao ^a   Ji, Pengyu ^a   Li, Zhuoyu ^a,b  

^a SHANXI UNIVERSITY   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Autophagy; Class III PI3K; Glycolysis; GRP78; NF B; PKM2

Indexed keywords

CARRIER PROTEIN; GLUCOSE; GLUCOSE TRANSPORTER 1; HEAT SHOCK PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTIC ACID; MEMBRANE PROTEIN; MOLECULAR CHAPERONE GRP78; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; THYROID HORMONE; THYROID HORMONE-BINDING PROTEINS;

ANTAGONISTS AND INHIBITORS; AUTOPHAGY; GENETICS; GLYCOLYSIS; HEK293 CELL LINE; HT 29 CELL LINE; HUMAN; METABOLISM; PROTEIN DOMAIN; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AUTOPHAGY; CARRIER PROTEINS; CELL LINE, TUMOR; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLYCOLYSIS; HEAT-SHOCK PROTEINS; HEK293 CELLS; HT29 CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; I-KAPPA B KINASE; LACTIC ACID; MEMBRANE PROTEINS; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN INTERACTION DOMAINS AND MOTIFS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THYROID HORMONES;

EID: 84939959368     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2015.02.030     Document Type: Article

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