Intracellular fibril formation, calcification, and enrichment of chaperones, cytoskeletal, and intermediate filament proteins in the adult hippocampus CA1 following neonatal exposure to the nonprotein amino acid BMAA

Archives of Toxicology

Volumn 89, Issue 3, 2015, Pages 423-436

  Karlsson, Oskar ^a   Berg, Anna Lena ^b,e   Hanrieder, Jörg ^c,d   Arnerup, Gunnel ^b   Lindström, Anna Karin ^b   Brittebo, Eva B ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

^c National Center for Imaging Mass Spectrometry   (Sweden)

^d CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^e MEDICAL PRODUCTS AGENCY   (Sweden)

Author keywords

Alexander disease; ALS PDC; Proteomics; TDP 43; Ubiquitin; Synuclein

Indexed keywords

ALPHA SYNUCLEIN; BETA-N-METHYLAMINO-L-ALANINE; CHAPERONE; CYTOSKELETON PROTEIN; DIAMINO ACID; UBIQUITIN;

ANIMAL; CALCINOSIS; CHEMICALLY INDUCED; CYTOSKELETON; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; HIPPOCAMPAL CA1 REGION; IMMUNOHISTOCHEMISTRY; LIQUID CHROMATOGRAPHY; METABOLISM; NEWBORN; PROTEIN FOLDING; SPRAGUE DAWLEY RAT; TANDEM MASS SPECTROMETRY; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ALPHA-SYNUCLEIN; AMINO ACIDS, DIAMINO; ANIMALS; ANIMALS, NEWBORN; CA1 REGION, HIPPOCAMPAL; CALCINOSIS; CHROMATOGRAPHY, LIQUID; CYTOSKELETAL PROTEINS; CYTOSKELETON; IMMUNOHISTOCHEMISTRY; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR CHAPERONES; PROTEIN FOLDING; RATS, SPRAGUE-DAWLEY; TANDEM MASS SPECTROMETRY; UBIQUITIN;

EID: 84939886627     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-014-1262-2     Document Type: Article

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