Amino acid analog toxicity in primary rat neuronal and astrocyte cultures: Implications for protein misfolding and TDP-43 regulation

Journal of Neuroscience Research

Volumn 89, Issue 9, 2011, Pages 1471-1477

  Dasuri, Kalavathi ^a   Ebenezer, Philip J ^a   Uranga, Romina M ^b   Gavilán, Elena ^c   Zhang, Le ^a   Fernandez Kim, Sun O K ^a   Bruce Keller, Annadora J ^a   Keller, Jeffrey N ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b UNIVERSIDAD NACIONAL DEL SUR   (Argentina)

^c UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Aging; Alzheimer's disease; Cell death; Neurodegeneration; Neurotoxicity; Protein aggregation; Ubiquitin

Indexed keywords

AZETIDINE 2 CARBOXYLIC ACID; CANAVANINE; DNA BINDING PROTEIN; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; TAR DNA BINDING PROTEIN 45; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL TYPE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; NERVE CELL; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN MISFOLDING; RAT; REGULATORY MECHANISM; UBIQUITINATION;

AMINO ACIDS; ANIMALS; ASTROCYTES; AZETIDINECARBOXYLIC ACID; CANAVANINE; CELL SURVIVAL; CELLS, CULTURED; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEAT-SHOCK PROTEINS; NEURONS; PROTEIN FOLDING; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 79960063693     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22677     Document Type: Article

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