Experience modulates the effects of histone deacetylase inhibitors on gene and protein expression in the hippocampus: Impaired plasticity in aging

Journal of Neuroscience

Volumn 35, Issue 33, 2015, Pages 11729-11742

  Sewal, Angila S ^a,b   Patzke, Holger ^c   Perez, Evelyn J ^a   Park, Pul ^a   Lehrmann, Elin ^a   Zhang, Yongqing ^a   Becker, Kevin G ^a   Fletcher, Bonnie R ^a   Long, Jeffrey M ^a   Rapp, Peter R ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c FORUM Pharmaceuticals   (United States)

Author keywords

Cognitive aging; Epigenetics; Histone acetylation; Microarray; Synaptic protein

Indexed keywords

DIMETHYL SULFOXIDE; HISTONE DEACETYLASE INHIBITOR; MEMBRANE PROTEIN; MESSENGER RNA; SYNAPTIC PROTEIN; UNCLASSIFIED DRUG; NERVE PROTEIN;

ADULT; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; COGNITION; CONTROLLED STUDY; GENE; GENE EXPRESSION; HIPPOCAMPUS; HISTONE ACETYLATION; IMMUNOCYTOCHEMISTRY; MALE; MEMORY DISORDER; MICROARRAY ANALYSIS; MORRIS WATER MAZE TEST; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; RNA ISOLATION; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; FISCHER 344 RAT; GENE EXPRESSION REGULATION; LONG TERM MEMORY; METABOLISM; PHYSIOLOGY;

AGING; ANIMALS; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HISTONE DEACETYLASE INHIBITORS; MALE; MEMORY, LONG-TERM; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; RATS; RATS, INBRED F344;

EID: 84939825291     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4339-14.2015     Document Type: Article

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