-
3
-
-
80054897554
-
Cutting edge issues in primary sclerosing cholangitis
-
COI: 1:CAS:528:DC%2BC3MXhtFyjs7nI, PID: 21170605
-
Bowlus CL (2011) Cutting edge issues in primary sclerosing cholangitis. Clin Rev Allergy Immunol 41:139–150
-
(2011)
Clin Rev Allergy Immunol
, vol.41
, pp. 139-150
-
-
Bowlus, C.L.1
-
4
-
-
84882846687
-
Update on primary sclerosing cholangitis
-
PID: 23603668
-
Karlsen TH, Boberg KM (2013) Update on primary sclerosing cholangitis. J Hepatol 59:571–582
-
(2013)
J Hepatol
, vol.59
, pp. 571-582
-
-
Karlsen, T.H.1
Boberg, K.M.2
-
5
-
-
33644617718
-
Etiopathogenesis of primary sclerosing cholangitis
-
PID: 16496229
-
O'Mahony CA, Vierling JM (2006) Etiopathogenesis of primary sclerosing cholangitis. Semin Liver Dis 26:3–21
-
(2006)
Semin Liver Dis
, vol.26
, pp. 3-21
-
-
O'Mahony, C.A.1
Vierling, J.M.2
-
6
-
-
54349125713
-
Etiopathogenesis of primary sclerosing cholangitis
-
COI: 1:CAS:528:DC%2BD1cXhtFylt7zP, PID: 18528932
-
Chapman R, Cullen S (2008) Etiopathogenesis of primary sclerosing cholangitis. World J Gastroenterol 14:3350–3359
-
(2008)
World J Gastroenterol
, vol.14
, pp. 3350-3359
-
-
Chapman, R.1
Cullen, S.2
-
7
-
-
82255177167
-
Pathogenesis of primary sclerosing cholangitis
-
COI: 1:CAS:528:DC%2BC3MXhsFGjt77K, PID: 22117638
-
Pollheimer MJ, Halilbasic E, Fickert P, Trauner M (2011) Pathogenesis of primary sclerosing cholangitis. Best Pract Res Clin Gastroenterol 25:727–739
-
(2011)
Best Pract Res Clin Gastroenterol
, vol.25
, pp. 727-739
-
-
Pollheimer, M.J.1
Halilbasic, E.2
Fickert, P.3
Trauner, M.4
-
8
-
-
24644507580
-
Immunopathogenesis of primary sclerosing cholangitis
-
COI: 1:CAS:528:DC%2BD2MXlslGmtbY%3D, PID: 15879616
-
Worthington J, Cullen S, Chapman R (2005) Immunopathogenesis of primary sclerosing cholangitis. Clin Rev Allergy Immunol 28:93–103
-
(2005)
Clin Rev Allergy Immunol
, vol.28
, pp. 93-103
-
-
Worthington, J.1
Cullen, S.2
Chapman, R.3
-
9
-
-
79958067265
-
Novel developments in IBD-related sclerosing cholangitis
-
PID: 21640925
-
Ponsioen CY (2011) Novel developments in IBD-related sclerosing cholangitis. Best Pract Res Clin Gastroenterol 25(Suppl 1):S15–S18. doi:10.1016/S1521-6918:-1
-
(2011)
Best Pract Res Clin Gastroenterol
, vol.25
, pp. S15-S18
-
-
Ponsioen, C.Y.1
-
10
-
-
0032773670
-
Immunohistochemical analysis of inflammation in primary sclerosing cholangitis
-
COI: 1:STN:280:DyaK1Mznt12ksg%3D%3D, PID: 10445798
-
Ponsioen CY, Kuiper H, ten Kate FJ, de van Milligen WM, van Deventer SJ, Tytgat GN (1999) Immunohistochemical analysis of inflammation in primary sclerosing cholangitis. Eur J Gastroenterol Hepatol 11:769–774
-
(1999)
Eur J Gastroenterol Hepatol
, vol.11
, pp. 769-774
-
-
Ponsioen, C.Y.1
Kuiper, H.2
ten Kate, F.J.3
de van Milligen, W.M.4
van Deventer, S.J.5
Tytgat, G.N.6
-
11
-
-
84893667590
-
CD8 T cells primed in the gut-associated lymphoid tissue induce immune-mediated cholangitis in mice
-
COI: 1:CAS:528:DC%2BC2cXhslygtL8%3D, PID: 24038154
-
Seidel D, Eickmeier I, Kuhl AA, Hamann A, Loddenkemper C, Schott E (2014) CD8 T cells primed in the gut-associated lymphoid tissue induce immune-mediated cholangitis in mice. Hepatology 59:601–611
-
(2014)
Hepatology
, vol.59
, pp. 601-611
-
-
Seidel, D.1
Eickmeier, I.2
Kuhl, A.A.3
Hamann, A.4
Loddenkemper, C.5
Schott, E.6
-
12
-
-
3242727039
-
Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice
-
COI: 1:CAS:528:DC%2BD2cXmsVShs7c%3D, PID: 15236191
-
Fickert P, Fuchsbichler A, Wagner M, Zollner G, Kaser A, Tilg H, Krause R, Lammert F, Langner C, Zatloukal K, Marschall HU, Denk H, Trauner M (2004) Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology 127:261–274
-
(2004)
Gastroenterology
, vol.127
, pp. 261-274
-
-
Fickert, P.1
Fuchsbichler, A.2
Wagner, M.3
Zollner, G.4
Kaser, A.5
Tilg, H.6
Krause, R.7
Lammert, F.8
Langner, C.9
Zatloukal, K.10
Marschall, H.U.11
Denk, H.12
Trauner, M.13
-
13
-
-
67649232094
-
A re-evaluation of the risk factors for the recurrence of primary sclerosing cholangitis in liver allografts
-
PID: 19243003
-
Alabraba E, Nightingale P, Gunson B, Hubscher S, Olliff S, Mirza D, Neuberger J (2009) A re-evaluation of the risk factors for the recurrence of primary sclerosing cholangitis in liver allografts. Liver Transpl 15:330–340
-
(2009)
Liver Transpl
, vol.15
, pp. 330-340
-
-
Alabraba, E.1
Nightingale, P.2
Gunson, B.3
Hubscher, S.4
Olliff, S.5
Mirza, D.6
Neuberger, J.7
-
14
-
-
84902075780
-
Systematic review: the epidemiology of the hepatobiliary manifestations in patients with inflammatory bowel disease
-
COI: 1:STN:280:DC%2BC2cjhsFeqsQ%3D%3D, PID: 24815622
-
Gizard E, Ford AC, Bronowicki JP, Peyrin-Biroulet L (2014) Systematic review: the epidemiology of the hepatobiliary manifestations in patients with inflammatory bowel disease. Aliment Pharmacol Ther 40:3–15
-
(2014)
Aliment Pharmacol Ther
, vol.40
, pp. 3-15
-
-
Gizard, E.1
Ford, A.C.2
Bronowicki, J.P.3
Peyrin-Biroulet, L.4
-
15
-
-
84902959665
-
Loss of CD28 expression by liver-infiltrating T cells contributes to pathogenesis of primary sclerosing cholangitis
-
COI: 1:CAS:528:DC%2BC2cXhtVemur3O, PID: 24726754
-
Liaskou E, Jeffery LE, Trivedi PJ, Reynolds GM, Suresh S, Bruns T, Adams DH, Sansom DM, Hirschfield GM (2014) Loss of CD28 expression by liver-infiltrating T cells contributes to pathogenesis of primary sclerosing cholangitis. Gastroenterology 147(1):221–232
-
(2014)
Gastroenterology
, vol.147
, Issue.1
, pp. 221-232
-
-
Liaskou, E.1
Jeffery, L.E.2
Trivedi, P.J.3
Reynolds, G.M.4
Suresh, S.5
Bruns, T.6
Adams, D.H.7
Sansom, D.M.8
Hirschfield, G.M.9
-
16
-
-
84871304988
-
The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice
-
COI: 1:CAS:528:DC%2BC38Xhs1CjsrbK, PID: 23041323
-
Alemi F, Poole DP, Chiu J, Schoonjans K, Cattaruzza F, Grider JR, Bunnett NW, Corvera CU (2013) The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice. Gastroenterology 144:145–154
-
(2013)
Gastroenterology
, vol.144
, pp. 145-154
-
-
Alemi, F.1
Poole, D.P.2
Chiu, J.3
Schoonjans, K.4
Cattaruzza, F.5
Grider, J.R.6
Bunnett, N.W.7
Corvera, C.U.8
-
17
-
-
84880136128
-
The bile acid receptor, TGR5, regulates basal and cholinergic-induced secretory responses in rat colon
-
COI: 1:CAS:528:DC%2BC3sXhsVOgurfI, PID: 23634890
-
Ward JB, Mroz MS, Keely SJ (2013) The bile acid receptor, TGR5, regulates basal and cholinergic-induced secretory responses in rat colon. Neurogastroenterol Motil 25:708–711
-
(2013)
Neurogastroenterol Motil
, vol.25
, pp. 708-711
-
-
Ward, J.B.1
Mroz, M.S.2
Keely, S.J.3
-
18
-
-
84876290819
-
TGR5 in cholangiocytes
-
COI: 1:CAS:528:DC%2BC3sXlslant7w%3D, PID: 23429467
-
Keitel V, Häussinger D (2013) TGR5 in cholangiocytes. Curr Opin Gastroenterol 29:299–304
-
(2013)
Curr Opin Gastroenterol
, vol.29
, pp. 299-304
-
-
Keitel, V.1
Häussinger, D.2
-
19
-
-
84868360297
-
Perspective: TGR5 (Gpbar-1) in liver physiology and disease
-
COI: 1:CAS:528:DC%2BC38XlvFKnsb0%3D, PID: 22521118
-
Keitel V, Häussinger D (2012) Perspective: TGR5 (Gpbar-1) in liver physiology and disease. Clin Res Hepatol Gastroenterol 36:412–419
-
(2012)
Clin Res Hepatol Gastroenterol
, vol.36
, pp. 412-419
-
-
Keitel, V.1
Häussinger, D.2
-
20
-
-
79959503376
-
TGR5 in the biliary tree
-
PID: 21691103
-
Keitel V, Häussinger D (2011) TGR5 in the biliary tree. Dig Dis 29:45–47
-
(2011)
Dig Dis
, vol.29
, pp. 45-47
-
-
Keitel, V.1
Häussinger, D.2
-
21
-
-
80055090450
-
The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis
-
COI: 1:CAS:528:DC%2BC3MXhsVyqtb7I, PID: 22046243
-
Cipriani S, Mencarelli A, Chini MG, Distrutti E, Renga B, Bifulco G, Baldelli F, Donini A, Fiorucci S (2011) The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis. PLoS One 6:e25637
-
(2011)
PLoS One
, vol.6
, pp. e25637
-
-
Cipriani, S.1
Mencarelli, A.2
Chini, M.G.3
Distrutti, E.4
Renga, B.5
Bifulco, G.6
Baldelli, F.7
Donini, A.8
Fiorucci, S.9
-
22
-
-
82955168360
-
TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading
-
COI: 1:CAS:528:DC%2BC3MXhs1Sktr7M, PID: 22152303
-
Pols TW, Nomura M, Harach T, Lo SG, Oosterveer MH, Thomas C, Rizzo G, Gioiello A, Adorini L, Pellicciari R, Auwerx J, Schoonjans K (2011) TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading. Cell Metab 14:747–757
-
(2011)
Cell Metab
, vol.14
, pp. 747-757
-
-
Pols, T.W.1
Nomura, M.2
Harach, T.3
Lo, S.G.4
Oosterveer, M.H.5
Thomas, C.6
Rizzo, G.7
Gioiello, A.8
Adorini, L.9
Pellicciari, R.10
Auwerx, J.11
Schoonjans, K.12
-
23
-
-
77954569180
-
The membrane-bound bile acid receptor TGR5 (Gpbar-1) is localized in the primary cilium of cholangiocytes
-
COI: 1:CAS:528:DC%2BC3cXptFWgtr4%3D, PID: 20623999
-
Keitel V, Ullmer C, Häussinger D (2010) The membrane-bound bile acid receptor TGR5 (Gpbar-1) is localized in the primary cilium of cholangiocytes. Biol Chem 391:785–789
-
(2010)
Biol Chem
, vol.391
, pp. 785-789
-
-
Keitel, V.1
Ullmer, C.2
Häussinger, D.3
-
24
-
-
70349255713
-
The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders
-
COI: 1:CAS:528:DC%2BD1MXhtFKntLzN, PID: 19582812
-
Keitel V, Cupisti K, Ullmer C, Knoefel WT, Kubitz R, Häussinger D (2009) The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders. Hepatology 50:861–870
-
(2009)
Hepatology
, vol.50
, pp. 861-870
-
-
Keitel, V.1
Cupisti, K.2
Ullmer, C.3
Knoefel, W.T.4
Kubitz, R.5
Häussinger, D.6
-
25
-
-
44649092024
-
Expression and function of the bile acid receptor TGR5 in Kupffer cells
-
COI: 1:CAS:528:DC%2BD1cXmvFeku7Y%3D, PID: 18468513
-
Keitel V, Donner M, Winandy S, Kubitz R, Häussinger D (2008) Expression and function of the bile acid receptor TGR5 in Kupffer cells. Biochem Biophys Res Commun 372:78–84
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 78-84
-
-
Keitel, V.1
Donner, M.2
Winandy, S.3
Kubitz, R.4
Häussinger, D.5
-
26
-
-
0003269455
-
A G protein-coupled receptor responsive to bile acids
-
COI: 1:CAS:528:DC%2BD3sXhvV2isrY%3D, PID: 12524422
-
Kawamata Y, Fujii R, Hosoya M, Harada M, Yoshida H, Miwa M, Fukusumi S, Habata Y, Itoh T, Shintani Y, Hinuma S, Fujisawa Y, Fujino M (2003) A G protein-coupled receptor responsive to bile acids. J Biol Chem 278:9435–9440
-
(2003)
J Biol Chem
, vol.278
, pp. 9435-9440
-
-
Kawamata, Y.1
Fujii, R.2
Hosoya, M.3
Harada, M.4
Yoshida, H.5
Miwa, M.6
Fukusumi, S.7
Habata, Y.8
Itoh, T.9
Shintani, Y.10
Hinuma, S.11
Fujisawa, Y.12
Fujino, M.13
-
27
-
-
0036432845
-
Identification of membrane-type receptor for bile acids (M-BAR)
-
COI: 1:CAS:528:DC%2BD38Xot12kt78%3D, PID: 12419312
-
Maruyama T, Miyamoto Y, Nakamura T, Tamai Y, Okada H, Sugiyama E, Nakamura T, Itadani H, Tanaka K (2002) Identification of membrane-type receptor for bile acids (M-BAR). Biochem Biophys Res Commun 298:714–719
-
(2002)
Biochem Biophys Res Commun
, vol.298
, pp. 714-719
-
-
Maruyama, T.1
Miyamoto, Y.2
Nakamura, T.3
Tamai, Y.4
Okada, H.5
Sugiyama, E.6
Nakamura, T.7
Itadani, H.8
Tanaka, K.9
-
28
-
-
41149144697
-
Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies
-
COI: 1:CAS:528:DC%2BD1cXis1ektLo%3D, PID: 18307294
-
Sato H, Macchiarulo A, Thomas C, Gioiello A, Une M, Hofmann AF, Saladin R, Schoonjans K, Pellicciari R, Auwerx J (2008) Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies. J Med Chem 51:1831–1841
-
(2008)
J Med Chem
, vol.51
, pp. 1831-1841
-
-
Sato, H.1
Macchiarulo, A.2
Thomas, C.3
Gioiello, A.4
Une, M.5
Hofmann, A.F.6
Saladin, R.7
Schoonjans, K.8
Pellicciari, R.9
Auwerx, J.10
-
29
-
-
80053308007
-
The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-kappaB) in mice
-
COI: 1:CAS:528:DC%2BC3MXht1amtbrM, PID: 21735468
-
Wang YD, Chen WD, Yu D, Forman BM, Huang W (2011) The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-kappaB) in mice. Hepatology 54:1421–1432
-
(2011)
Hepatology
, vol.54
, pp. 1421-1432
-
-
Wang, Y.D.1
Chen, W.D.2
Yu, D.3
Forman, B.M.4
Huang, W.5
-
30
-
-
84878631549
-
Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling
-
COI: 1:CAS:528:DC%2BC3sXhtV2jurjJ, PID: 23578785
-
Masyuk AI, Huang BQ, Radtke BN, Gajdos GB, Splinter PL, Masyuk TV, Gradilone SA, LaRusso NF (2013) Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling. Am J Physiol Gastrointest Liver Physiol 304:G1013–G1024
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.304
, pp. G1013-G1024
-
-
Masyuk, A.I.1
Huang, B.Q.2
Radtke, B.N.3
Gajdos, G.B.4
Splinter, P.L.5
Masyuk, T.V.6
Gradilone, S.A.7
LaRusso, N.F.8
-
31
-
-
84859908601
-
The biliary HCO(3)(-) umbrella: experimental evidence revisited
-
COI: 1:CAS:528:DC%2BC38Xls1Snt7w%3D, PID: 22450897
-
Beuers U, Maroni L, Elferink RO (2012) The biliary HCO(3)(-) umbrella: experimental evidence revisited. Curr Opin Gastroenterol 28:253–257
-
(2012)
Curr Opin Gastroenterol
, vol.28
, pp. 253-257
-
-
Beuers, U.1
Maroni, L.2
Elferink, R.O.3
-
32
-
-
77957940106
-
The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies
-
COI: 1:CAS:528:DC%2BC3cXhtlejsrbO, PID: 20721884
-
Beuers U, Hohenester S, de Buy Wenniger LJ, Kremer AE, Jansen PL, Elferink RP (2010) The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies. Hepatology 52:1489–1496
-
(2010)
Hepatology
, vol.52
, pp. 1489-1496
-
-
Beuers, U.1
Hohenester, S.2
de Buy Wenniger, L.J.3
Kremer, A.E.4
Jansen, P.L.5
Elferink, R.P.6
-
33
-
-
84155175630
-
A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes
-
COI: 1:CAS:528:DC%2BC3MXhs1Ght7zN, PID: 21932391
-
Hohenester S, Wenniger LM, Paulusma CC, van Vliet SJ, Jefferson DM, Elferink RP, Beuers U (2012) A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes. Hepatology 55:173–183
-
(2012)
Hepatology
, vol.55
, pp. 173-183
-
-
Hohenester, S.1
Wenniger, L.M.2
Paulusma, C.C.3
van Vliet, S.J.4
Jefferson, D.M.5
Elferink, R.P.6
Beuers, U.7
-
34
-
-
1242317704
-
The SLC4 family of HCO 3 - transporters
-
COI: 1:CAS:528:DC%2BD2cXhtVygt7s%3D, PID: 14722772
-
Romero MF, Fulton CM, Boron WF (2004) The SLC4 family of HCO 3 - transporters. Pflugers Arch 447:495–509
-
(2004)
Pflugers Arch
, vol.447
, pp. 495-509
-
-
Romero, M.F.1
Fulton, C.M.2
Boron, W.F.3
-
35
-
-
43049094474
-
Ae2a, b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis
-
COI: 1:CAS:528:DC%2BD1cXntVWhu7o%3D, PID: 18471521
-
Salas JT, Banales JM, Sarvide S, Recalde S, Ferrer A, Uriarte I, Oude Elferink RP, Prieto J, Medina JF (2008) Ae2a, b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis. Gastroenterology 134:1482–1493
-
(2008)
Gastroenterology
, vol.134
, pp. 1482-1493
-
-
Salas, J.T.1
Banales, J.M.2
Sarvide, S.3
Recalde, S.4
Ferrer, A.5
Uriarte, I.6
Oude Elferink, R.P.7
Prieto, J.8
Medina, J.F.9
-
36
-
-
18544371193
-
Defective regulation of cholangiocyte Cl-/HCO3(-) and Na+/H+ exchanger activities in primary biliary cirrhosis
-
COI: 1:CAS:528:DC%2BD38XkvFSntr4%3D, PID: 12029638
-
Melero S, Spirli C, Zsembery A, Medina JF, Joplin RE, Duner E, Zuin M, Neuberger JM, Prieto J, Strazzabosco M (2002) Defective regulation of cholangiocyte Cl-/HCO3(-) and Na+/H+ exchanger activities in primary biliary cirrhosis. Hepatology 35:1513–1521
-
(2002)
Hepatology
, vol.35
, pp. 1513-1521
-
-
Melero, S.1
Spirli, C.2
Zsembery, A.3
Medina, J.F.4
Joplin, R.E.5
Duner, E.6
Zuin, M.7
Neuberger, J.M.8
Prieto, J.9
Strazzabosco, M.10
-
37
-
-
0030952659
-
Na(+)-dependent and -independent Cl-/HCO-3 exchange mediate cellular HCO3- transport in cultured human intrahepatic bile duct cells
-
COI: 1:CAS:528:DyaK2sXislejur8%3D, PID: 9096607
-
Strazzabosco M, Joplin R, Zsembery A, Wallace L, Spirli C, Fabris L, Granato A, Rossanese A, Poci C, Neuberger JM, Okolicsanyi L, Crepaldi G (1997) Na(+)-dependent and -independent Cl-/HCO-3 exchange mediate cellular HCO3- transport in cultured human intrahepatic bile duct cells. Hepatology 25:976–985
-
(1997)
Hepatology
, vol.25
, pp. 976-985
-
-
Strazzabosco, M.1
Joplin, R.2
Zsembery, A.3
Wallace, L.4
Spirli, C.5
Fabris, L.6
Granato, A.7
Rossanese, A.8
Poci, C.9
Neuberger, J.M.10
Okolicsanyi, L.11
Crepaldi, G.12
-
38
-
-
77950617298
-
Bicarbonate secretion of mouse cholangiocytes involves Na(+)-HCO(3)(-) cotransport in addition to Na(+)-independent Cl(-)/HCO(3)(-) exchange
-
COI: 1:CAS:528:DC%2BC3cXks1Sqs70%3D, PID: 20041402
-
Uriarte I, Banales JM, Saez E, Arenas F, Oude Elferink RP, Prieto J, Medina JF (2010) Bicarbonate secretion of mouse cholangiocytes involves Na(+)-HCO(3)(-) cotransport in addition to Na(+)-independent Cl(-)/HCO(3)(-) exchange. Hepatology 51:891–902
-
(2010)
Hepatology
, vol.51
, pp. 891-902
-
-
Uriarte, I.1
Banales, J.M.2
Saez, E.3
Arenas, F.4
Oude Elferink, R.P.5
Prieto, J.6
Medina, J.F.7
-
39
-
-
17944371738
-
Secretin activation of the apical Na+-dependent bile acid transporter is associated with cholehepatic shunting in rats
-
COI: 1:CAS:528:DC%2BD2MXksF2hsLc%3D, PID: 15834929
-
Alpini G, Glaser S, Baiocchi L, Francis H, Xia X, LeSage G (2005) Secretin activation of the apical Na+-dependent bile acid transporter is associated with cholehepatic shunting in rats. Hepatology 41:1037–1045
-
(2005)
Hepatology
, vol.41
, pp. 1037-1045
-
-
Alpini, G.1
Glaser, S.2
Baiocchi, L.3
Francis, H.4
Xia, X.5
LeSage, G.6
-
40
-
-
0033852384
-
Forskolin-induced apical membrane insertion of virally expressed, epitope-tagged CFTR in polarized MDCK cells
-
COI: 1:CAS:528:DC%2BD3cXmtFyjsL0%3D, PID: 10913004
-
Howard M, Jiang X, Stolz DB, Hill WG, Johnson JA, Watkins SC, Frizzell RA, Bruton CM, Robbins PD, Weisz OA (2000) Forskolin-induced apical membrane insertion of virally expressed, epitope-tagged CFTR in polarized MDCK cells. Am J Physiol Cell Physiol 279:C375–C382
-
(2000)
Am J Physiol Cell Physiol
, vol.279
, pp. C375-C382
-
-
Howard, M.1
Jiang, X.2
Stolz, D.B.3
Hill, W.G.4
Johnson, J.A.5
Watkins, S.C.6
Frizzell, R.A.7
Bruton, C.M.8
Robbins, P.D.9
Weisz, O.A.10
-
41
-
-
79957663467
-
The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling
-
COI: 1:CAS:528:DC%2BC3MXnsl2msLs%3D, PID: 21454404
-
Li T, Holmstrom SR, Kir S, Umetani M, Schmidt DR, Kliewer SA, Mangelsdorf DJ (2011) The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling. Mol Endocrinol 25:1066–1071
-
(2011)
Mol Endocrinol
, vol.25
, pp. 1066-1071
-
-
Li, T.1
Holmstrom, S.R.2
Kir, S.3
Umetani, M.4
Schmidt, D.R.5
Kliewer, S.A.6
Mangelsdorf, D.J.7
-
42
-
-
73249142867
-
Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity
-
COI: 1:CAS:528:DC%2BD1MXhsVSgtL%2FE, PID: 20014870
-
Pellicciari R, Gioiello A, Macchiarulo A, Thomas C, Rosatelli E, Natalini B, Sardella R, Pruzanski M, Roda A, Pastorini E, Schoonjans K, Auwerx J (2009) Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity. J Med Chem 52:7958–7961
-
(2009)
J Med Chem
, vol.52
, pp. 7958-7961
-
-
Pellicciari, R.1
Gioiello, A.2
Macchiarulo, A.3
Thomas, C.4
Rosatelli, E.5
Natalini, B.6
Sardella, R.7
Pruzanski, M.8
Roda, A.9
Pastorini, E.10
Schoonjans, K.11
Auwerx, J.12
-
43
-
-
0030760489
-
Bile acids stimulate proliferative and secretory events in large but not small cholangiocytes
-
COI: 1:CAS:528:DyaK2sXlslegsrg%3D, PID: 9277433
-
Alpini G, Glaser S, Robertson W, Phinizy JL, Rodgers RE, Caligiuri A, LeSage G (1997) Bile acids stimulate proliferative and secretory events in large but not small cholangiocytes. Am J Physiol 273:G518–G529
-
(1997)
Am J Physiol
, vol.273
, pp. G518-G529
-
-
Alpini, G.1
Glaser, S.2
Robertson, W.3
Phinizy, J.L.4
Rodgers, R.E.5
Caligiuri, A.6
LeSage, G.7
-
44
-
-
0032899948
-
Bile acid feeding induces cholangiocyte proliferation and secretion: evidence for bile acid-regulated ductal secretion
-
COI: 1:CAS:528:DyaK1MXlsl2ntg%3D%3D, PID: 9869616
-
Alpini G, Glaser SS, Ueno Y, Rodgers R, Phinizy JL, Francis H, Baiocchi L, Holcomb LA, Caligiuri A, LeSage GD (1999) Bile acid feeding induces cholangiocyte proliferation and secretion: evidence for bile acid-regulated ductal secretion. Gastroenterology 116:179–186
-
(1999)
Gastroenterology
, vol.116
, pp. 179-186
-
-
Alpini, G.1
Glaser, S.S.2
Ueno, Y.3
Rodgers, R.4
Phinizy, J.L.5
Francis, H.6
Baiocchi, L.7
Holcomb, L.A.8
Caligiuri, A.9
LeSage, G.D.10
-
45
-
-
33947383769
-
The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells
-
COI: 1:CAS:528:DC%2BD2sXjs1Gku74%3D, PID: 17326144
-
Keitel V, Reinehr R, Gatsios P, Rupprecht C, Görg B, Selbach O, Häussinger D, Kubitz R (2007) The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells. Hepatology 45:695–704
-
(2007)
Hepatology
, vol.45
, pp. 695-704
-
-
Keitel, V.1
Reinehr, R.2
Gatsios, P.3
Rupprecht, C.4
Görg, B.5
Selbach, O.6
Häussinger, D.7
Kubitz, R.8
-
46
-
-
0347361545
-
Inhibition of bile salt-induced apoptosis by cyclic AMP involves serine/threonine phosphorylation of CD95
-
COI: 1:CAS:528:DC%2BD2cXhtFGntbk%3D, PID: 14699504
-
Reinehr R, Häussinger D (2004) Inhibition of bile salt-induced apoptosis by cyclic AMP involves serine/threonine phosphorylation of CD95. Gastroenterology 126:249–262
-
(2004)
Gastroenterology
, vol.126
, pp. 249-262
-
-
Reinehr, R.1
Häussinger, D.2
-
47
-
-
84871242636
-
The membrane-bound bile acid receptor TGR5 (Gpbar-1) is highly expressed in intrahepatic cholangiocarcinoma (abstract)
-
Keitel V, Reinehr R, Reich M, Sommerfeld A, Cupisti K, Knoefel WT, Häussinger D (2011) The membrane-bound bile acid receptor TGR5 (Gpbar-1) is highly expressed in intrahepatic cholangiocarcinoma (abstract). Hepatology 54:869
-
(2011)
Hepatology
, vol.54
, pp. 869
-
-
Keitel, V.1
Reinehr, R.2
Reich, M.3
Sommerfeld, A.4
Cupisti, K.5
Knoefel, W.T.6
Häussinger, D.7
-
48
-
-
84888798215
-
Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages
-
PID: 23990628
-
Haselow K, Bode JG, Wammers M, Ehlting C, Keitel V, Kleinebrecht L, Schupp AK, Häussinger D, Graf D (2013) Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages. J Leukoc Biol 94:1253–1264
-
(2013)
J Leukoc Biol
, vol.94
, pp. 1253-1264
-
-
Haselow, K.1
Bode, J.G.2
Wammers, M.3
Ehlting, C.4
Keitel, V.5
Kleinebrecht, L.6
Schupp, A.K.7
Häussinger, D.8
Graf, D.9
-
49
-
-
84871358978
-
Bile acids as extrahepatic and interorgan signaling molecules
-
Häussinger D, Keitel V, Kubitz R, (eds), DeGruyter Publishing, Berlin:
-
Keitel V (2012) Bile acids as extrahepatic and interorgan signaling molecules. In: Häussinger D, Keitel V, Kubitz R (eds) Hepatobiliary transport in health and disease. DeGruyter Publishing, Berlin, pp 117–129
-
(2012)
Hepatobiliary transport in health and disease
, pp. 117-129
-
-
Keitel, V.1
-
50
-
-
84876041065
-
TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn’s disease
-
COI: 1:CAS:528:DC%2BC3sXlsVCktr8%3D, PID: 23566200
-
Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume MT, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T (2013) TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn’s disease. Immunology 139:19–29
-
(2013)
Immunology
, vol.139
, pp. 19-29
-
-
Yoneno, K.1
Hisamatsu, T.2
Shimamura, K.3
Kamada, N.4
Ichikawa, R.5
Kitazume, M.T.6
Mori, M.7
Uo, M.8
Namikawa, Y.9
Matsuoka, K.10
Sato, T.11
Koganei, K.12
Sugita, A.13
Kanai, T.14
Hibi, T.15
-
51
-
-
77953352917
-
Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system
-
COI: 1:CAS:528:DC%2BC3cXps1emt7s%3D, PID: 20236244
-
Poole DP, Godfrey C, Cattaruzza F, Cottrell GS, Kirkland JG, Pelayo JC, Bunnett NW, Corvera CU (2010) Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system. Neurogastroenterol Motil 22:814–825
-
(2010)
Neurogastroenterol Motil
, vol.22
, pp. 814-825
-
-
Poole, D.P.1
Godfrey, C.2
Cattaruzza, F.3
Cottrell, G.S.4
Kirkland, J.G.5
Pelayo, J.C.6
Bunnett, N.W.7
Corvera, C.U.8
-
52
-
-
69149083245
-
TGR5-mediated bile acid sensing controls glucose homeostasis
-
COI: 1:CAS:528:DC%2BD1MXhsVChtLnM, PID: 19723493
-
Thomas C, Gioiello A, Noriega L, Strehle A, Oury J, Rizzo G, Macchiarulo A, Yamamoto H, Mataki C, Pruzanski M, Pellicciari R, Auwerx J, Schoonjans K (2009) TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab 10:167–177
-
(2009)
Cell Metab
, vol.10
, pp. 167-177
-
-
Thomas, C.1
Gioiello, A.2
Noriega, L.3
Strehle, A.4
Oury, J.5
Rizzo, G.6
Macchiarulo, A.7
Yamamoto, H.8
Mataki, C.9
Pruzanski, M.10
Pellicciari, R.11
Auwerx, J.12
Schoonjans, K.13
-
53
-
-
80053909415
-
Association of bile acid receptor TGR5 variation and transit in health and lower functional gastrointestinal disorders
-
COI: 1:CAS:528:DC%2BC3MXhsFamsr%2FK, PID: 21883702, e458
-
Camilleri M, Vazquez-Roque MI, Carlson P, Burton D, Wong BS, Zinsmeister AR (2011) Association of bile acid receptor TGR5 variation and transit in health and lower functional gastrointestinal disorders. Neurogastroenterol Motil 23:995–999, e458
-
(2011)
Neurogastroenterol Motil
, vol.23
, pp. 995-999
-
-
Camilleri, M.1
Vazquez-Roque, M.I.2
Carlson, P.3
Burton, D.4
Wong, B.S.5
Zinsmeister, A.R.6
-
54
-
-
79956088562
-
The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation
-
COI: 1:CAS:528:DC%2BC3MXmsVygtrg%3D, PID: 21145931
-
Pols TW, Noriega LG, Nomura M, Auwerx J, Schoonjans K (2011) The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation. J Hepatol 54:1263–1272
-
(2011)
J Hepatol
, vol.54
, pp. 1263-1272
-
-
Pols, T.W.1
Noriega, L.G.2
Nomura, M.3
Auwerx, J.4
Schoonjans, K.5
-
55
-
-
33748757234
-
Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation
-
COI: 1:CAS:528:DC%2BD28XoslGlurg%3D, PID: 16724960
-
Vassileva G, Golovko A, Markowitz L, Abbondanzo SJ, Zeng M, Yang S, Hoos L, Tetzloff G, Levitan D, Murgolo NJ, Keane K, Davis HR Jr, Hedrick J, Gustafson EL (2006) Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation. Biochem J 398:423–430
-
(2006)
Biochem J
, vol.398
, pp. 423-430
-
-
Vassileva, G.1
Golovko, A.2
Markowitz, L.3
Abbondanzo, S.J.4
Zeng, M.5
Yang, S.6
Hoos, L.7
Tetzloff, G.8
Levitan, D.9
Murgolo, N.J.10
Keane, K.11
Davis, H.R.12
Hedrick, J.13
Gustafson, E.L.14
-
56
-
-
77952562273
-
Gender-dependent effect of Gpbar1 genetic deletion on the metabolic profiles of diet-induced obese mice
-
COI: 1:CAS:528:DC%2BC3cXnslCntLg%3D, PID: 20354075
-
Vassileva G, Hu W, Hoos L, Tetzloff G, Yang S, Liu L, Kang L, Davis HR, Hedrick JA, Lan H, Kowalski T, Gustafson EL (2010) Gender-dependent effect of Gpbar1 genetic deletion on the metabolic profiles of diet-induced obese mice. J Endocrinol 205:225–232
-
(2010)
J Endocrinol
, vol.205
, pp. 225-232
-
-
Vassileva, G.1
Hu, W.2
Hoos, L.3
Tetzloff, G.4
Yang, S.5
Liu, L.6
Kang, L.7
Davis, H.R.8
Hedrick, J.A.9
Lan, H.10
Kowalski, T.11
Gustafson, E.L.12
-
57
-
-
33751066787
-
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice
-
COI: 1:CAS:528:DC%2BD28Xht1eju7bI, PID: 17065403
-
Maruyama T, Tanaka K, Suzuki J, Miyoshi H, Harada N, Nakamura T, Miyamoto Y, Kanatani A, Tamai Y (2006) Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice. J Endocrinol 191:197–205
-
(2006)
J Endocrinol
, vol.191
, pp. 197-205
-
-
Maruyama, T.1
Tanaka, K.2
Suzuki, J.3
Miyoshi, H.4
Harada, N.5
Nakamura, T.6
Miyamoto, Y.7
Kanatani, A.8
Tamai, Y.9
-
58
-
-
55049111426
-
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
-
COI: 1:CAS:528:DC%2BD1cXhtlSkurjI, PID: 18836448
-
Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, Mayr G, Domingues FS, Albrecht M, Nothnagel M, Ellinghaus D, Sina C, Onnie CM, Weersma RK, Stokkers PC, Wijmenga C, Gazouli M, Strachan D, McArdle WL, Vermeire S, Rutgeerts P, Rosenstiel P, Krawczak M, Vatn MH, Mathew CG, Schreiber S (2008) Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet 40:1319–1323
-
(2008)
Nat Genet
, vol.40
, pp. 1319-1323
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Sventoraityte, J.4
Nikolaus, S.5
Mayr, G.6
Domingues, F.S.7
Albrecht, M.8
Nothnagel, M.9
Ellinghaus, D.10
Sina, C.11
Onnie, C.M.12
Weersma, R.K.13
Stokkers, P.C.14
Wijmenga, C.15
Gazouli, M.16
Strachan, D.17
McArdle, W.L.18
Vermeire, S.19
Rutgeerts, P.20
Rosenstiel, P.21
Krawczak, M.22
Vatn, M.H.23
Mathew, C.G.24
Schreiber, S.25
more..
-
59
-
-
77249164222
-
Genome-wide association analysis in primary sclerosing cholangitis
-
PID: 19944697
-
Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Weismuller TJ, Gotthardt D, Rust C, Philipp EE, Fritz T, Henckaerts L, Weersma RK, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P, Stiehl A, Vermeire S, Beuers U, Manns MP, Schrumpf E, Boberg KM, Schreiber S (2010) Genome-wide association analysis in primary sclerosing cholangitis. Gastroenterology 138:1102–1111
-
(2010)
Gastroenterology
, vol.138
, pp. 1102-1111
-
-
Karlsen, T.H.1
Franke, A.2
Melum, E.3
Kaser, A.4
Hov, J.R.5
Balschun, T.6
Lie, B.A.7
Bergquist, A.8
Schramm, C.9
Weismuller, T.J.10
Gotthardt, D.11
Rust, C.12
Philipp, E.E.13
Fritz, T.14
Henckaerts, L.15
Weersma, R.K.16
Stokkers, P.17
Ponsioen, C.Y.18
Wijmenga, C.19
Sterneck, M.20
Nothnagel, M.21
Hampe, J.22
Teufel, A.23
Runz, H.24
Rosenstiel, P.25
Stiehl, A.26
Vermeire, S.27
Beuers, U.28
Manns, M.P.29
Schrumpf, E.30
Boberg, K.M.31
Schreiber, S.32
more..
-
60
-
-
77957877682
-
Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis
-
PID: 20811628
-
Hov JR, Keitel V, Laerdahl JK, Spomer L, Ellinghaus E, ElSharawy A, Melum E, Boberg KM, Manke T, Balschun T, Schramm C, Bergquist A, Weismuller T, Gotthardt D, Rust C, Henckaerts L, Onnie CM, Weersma RK, Sterneck M, Teufel A, Runz H, Stiehl A, Ponsioen CY, Wijmenga C, Vatn MH, Stokkers PC, Vermeire S, Mathew CG, Lie BA, Beuers U, Manns MP, Schreiber S, Schrumpf E, Häussinger D, Franke A, Karlsen TH (2010) Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis. PLoS One 5:e12403
-
(2010)
PLoS One
, vol.5
, pp. e12403
-
-
Hov, J.R.1
Keitel, V.2
Laerdahl, J.K.3
Spomer, L.4
Ellinghaus, E.5
ElSharawy, A.6
Melum, E.7
Boberg, K.M.8
Manke, T.9
Balschun, T.10
Schramm, C.11
Bergquist, A.12
Weismuller, T.13
Gotthardt, D.14
Rust, C.15
Henckaerts, L.16
Onnie, C.M.17
Weersma, R.K.18
Sterneck, M.19
Teufel, A.20
Runz, H.21
Stiehl, A.22
Ponsioen, C.Y.23
Wijmenga, C.24
Vatn, M.H.25
Stokkers, P.C.26
Vermeire, S.27
Mathew, C.G.28
Lie, B.A.29
Beuers, U.30
Manns, M.P.31
Schreiber, S.32
Schrumpf, E.33
Häussinger, D.34
Franke, A.35
Karlsen, T.H.36
more..
-
61
-
-
0036192231
-
Hepatic and extrahepatic malignancies in primary sclerosing cholangitis
-
PID: 11867174
-
Bergquist A, Ekbom A, Olsson R, Kornfeldt D, Loof L, Danielsson A, Hultcrantz R, Lindgren S, Prytz H, Sandberg-Gertzen H, Almer S, Granath F, Broome U (2002) Hepatic and extrahepatic malignancies in primary sclerosing cholangitis. J Hepatol 36:321–327
-
(2002)
J Hepatol
, vol.36
, pp. 321-327
-
-
Bergquist, A.1
Ekbom, A.2
Olsson, R.3
Kornfeldt, D.4
Loof, L.5
Danielsson, A.6
Hultcrantz, R.7
Lindgren, S.8
Prytz, H.9
Sandberg-Gertzen, H.10
Almer, S.11
Granath, F.12
Broome, U.13
-
62
-
-
84867713233
-
Primary sclerosing cholangitis: new approaches to diagnosis, surveillance and treatment
-
PID: 23075867
-
Trauner M, Halilbasic E, Baghdasaryan A, Moustafa T, Krones E, Fickert P, Hofer H, Penner E (2012) Primary sclerosing cholangitis: new approaches to diagnosis, surveillance and treatment. Dig Dis 30(Suppl 1):39–47. doi:10.1159/000341123.:39-47
-
(2012)
Dig Dis
, vol.30
, pp. 39-47
-
-
Trauner, M.1
Halilbasic, E.2
Baghdasaryan, A.3
Moustafa, T.4
Krones, E.5
Fickert, P.6
Hofer, H.7
Penner, E.8
-
63
-
-
0028831047
-
Unconjugated secondary bile acids in the serum of patients with colorectal adenomas
-
COI: 1:STN:280:DyaK2M7ovFWntA%3D%3D, PID: 7883228
-
Bayerdorffer E, Mannes GA, Ochsenkuhn T, Dirschedl P, Wiebecke B, Paumgartner G (1995) Unconjugated secondary bile acids in the serum of patients with colorectal adenomas. Gut 36:268–273
-
(1995)
Gut
, vol.36
, pp. 268-273
-
-
Bayerdorffer, E.1
Mannes, G.A.2
Ochsenkuhn, T.3
Dirschedl, P.4
Wiebecke, B.5
Paumgartner, G.6
-
64
-
-
0027571014
-
Biliary bile acids in cholelithiasis and carcinoma of the gall bladder
-
COI: 1:STN:280:DyaK3s3hsVKjsw%3D%3D, PID: 8461866
-
Shukla VK, Tiwari SC, Roy SK (1993) Biliary bile acids in cholelithiasis and carcinoma of the gall bladder. Eur J Cancer Prev 2:155–160
-
(1993)
Eur J Cancer Prev
, vol.2
, pp. 155-160
-
-
Shukla, V.K.1
Tiwari, S.C.2
Roy, S.K.3
-
65
-
-
80052739162
-
Carcinogenicity of deoxycholate, a secondary bile acid
-
COI: 1:CAS:528:DC%2BC3MXhtVers78%3D, PID: 21267546
-
Bernstein C, Holubec H, Bhattacharyya AK, Nguyen H, Payne CM, Zaitlin B, Bernstein H (2011) Carcinogenicity of deoxycholate, a secondary bile acid. Arch Toxicol 85:863–871
-
(2011)
Arch Toxicol
, vol.85
, pp. 863-871
-
-
Bernstein, C.1
Holubec, H.2
Bhattacharyya, A.K.3
Nguyen, H.4
Payne, C.M.5
Zaitlin, B.6
Bernstein, H.7
-
66
-
-
11244335567
-
Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy
-
PID: 15690474
-
Sirica AE (2005) Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy. Hepatology 41:5–15
-
(2005)
Hepatology
, vol.41
, pp. 5-15
-
-
Sirica, A.E.1
-
67
-
-
47149112544
-
Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment
-
COI: 1:CAS:528:DC%2BD1cXptFemu70%3D, PID: 18536057
-
Blechacz B, Gores GJ (2008) Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment. Hepatology 48:308–321
-
(2008)
Hepatology
, vol.48
, pp. 308-321
-
-
Blechacz, B.1
Gores, G.J.2
-
68
-
-
84875848761
-
The TGR5 receptor mediates bile acid-induced itch and analgesia
-
COI: 1:CAS:528:DC%2BC3sXlvVKhsL8%3D, PID: 23524965
-
Alemi F, Kwon E, Poole DP, Lieu T, Lyo V, Cattaruzza F, Cevikbas F, Steinhoff M, Nassini R, Materazzi S, Guerrero-Alba R, Valdez-Morales E, Cottrell GS, Schoonjans K, Geppetti P, Vanner SJ, Bunnett NW, Corvera CU (2013) The TGR5 receptor mediates bile acid-induced itch and analgesia. J Clin Invest 123:1513–1530
-
(2013)
J Clin Invest
, vol.123
, pp. 1513-1530
-
-
Alemi, F.1
Kwon, E.2
Poole, D.P.3
Lieu, T.4
Lyo, V.5
Cattaruzza, F.6
Cevikbas, F.7
Steinhoff, M.8
Nassini, R.9
Materazzi, S.10
Guerrero-Alba, R.11
Valdez-Morales, E.12
Cottrell, G.S.13
Schoonjans, K.14
Geppetti, P.15
Vanner, S.J.16
Bunnett, N.W.17
Corvera, C.U.18
-
69
-
-
78649386642
-
The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain
-
PID: 20665558
-
Keitel V, Görg B, Bidmon HJ, Zemtsova I, Spomer L, Zilles K, Häussinger D (2010) The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain. Glia 58:1794–1805
-
(2010)
Glia
, vol.58
, pp. 1794-1805
-
-
Keitel, V.1
Görg, B.2
Bidmon, H.J.3
Zemtsova, I.4
Spomer, L.5
Zilles, K.6
Häussinger, D.7
-
70
-
-
75449104123
-
Diagnosis and management of primary sclerosing cholangitis
-
COI: 1:CAS:528:DC%2BC3cXisVGnsrg%3D, PID: 20101749
-
Chapman R, Fevery J, Kalloo A, Nagorney DM, Boberg KM, Shneider B, Gores GJ (2010) Diagnosis and management of primary sclerosing cholangitis. Hepatology 51:660–678
-
(2010)
Hepatology
, vol.51
, pp. 660-678
-
-
Chapman, R.1
Fevery, J.2
Kalloo, A.3
Nagorney, D.M.4
Boberg, K.M.5
Shneider, B.6
Gores, G.J.7
-
71
-
-
67649205149
-
-
EASL clinical practice guidelines: management of cholestatic liver diseases. J Hepatol 2009; 51:237–67
-
EASL clinical practice guidelines: management of cholestatic liver diseases. J Hepatol 2009; 51:237–67
-
-
-
-
72
-
-
0030012966
-
Effects of ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene
-
PID: 8698195
-
Van Nieuwkerk CM, Elferink RP, Groen AK, Ottenhoff R, Tytgat GN, Dingemans KP, Van Den Bergh Weerman MA, Offerhaus GJ (1996) Effects of ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene. Gastroenterology 111:165–171
-
(1996)
Gastroenterology
, vol.111
, pp. 165-171
-
-
Van Nieuwkerk, C.M.1
Elferink, R.P.2
Groen, A.K.3
Ottenhoff, R.4
Tytgat, G.N.5
Dingemans, K.P.6
Van Den Bergh Weerman, M.A.7
Offerhaus, G.J.8
-
73
-
-
80053334403
-
Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO output
-
COI: 1:CAS:528:DC%2BC3MXht1amtb3P, PID: 22006858
-
Baghdasaryan A, Claudel T, Gumhold J, Silbert D, Adorini L, Roda A, Vecchiotti S, Gonzalez FJ, Schoonjans K, Strazzabosco M, Fickert P, Trauner M (2011) Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO output. Hepatology 54:1303–1312
-
(2011)
Hepatology
, vol.54
, pp. 1303-1312
-
-
Baghdasaryan, A.1
Claudel, T.2
Gumhold, J.3
Silbert, D.4
Adorini, L.5
Roda, A.6
Vecchiotti, S.7
Gonzalez, F.J.8
Schoonjans, K.9
Strazzabosco, M.10
Fickert, P.11
Trauner, M.12
-
74
-
-
77149120776
-
Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma
-
COI: 1:CAS:528:DC%2BC3cXjsFeqsLo%3D, PID: 19926617
-
Hong J, Behar J, Wands J, Resnick M, Wang LJ, DeLellis RA, Lambeth D, Souza RF, Spechler SJ, Cao W (2010) Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma. Gut 59:170–180
-
(2010)
Gut
, vol.59
, pp. 170-180
-
-
Hong, J.1
Behar, J.2
Wands, J.3
Resnick, M.4
Wang, L.J.5
DeLellis, R.A.6
Lambeth, D.7
Souza, R.F.8
Spechler, S.J.9
Cao, W.10
-
75
-
-
33846345695
-
Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells
-
COI: 1:CAS:528:DC%2BD2sXhtVClsr8%3D, PID: 17214962
-
Yasuda H, Hirata S, Inoue K, Mashima H, Ohnishi H, Yoshiba M (2007) Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells. Biochem Biophys Res Commun 354:154–159
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 154-159
-
-
Yasuda, H.1
Hirata, S.2
Inoue, K.3
Mashima, H.4
Ohnishi, H.5
Yoshiba, M.6
-
76
-
-
0032944048
-
Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone
-
COI: 1:CAS:528:DyaK1MXht1Cgsbk%3D, PID: 9922322
-
Kubitz R, Wettstein M, Warskulat U, Häussinger D (1999) Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone. Gastroenterology 116:401–410
-
(1999)
Gastroenterology
, vol.116
, pp. 401-410
-
-
Kubitz, R.1
Wettstein, M.2
Warskulat, U.3
Häussinger, D.4
-
77
-
-
85055815953
-
Bile acid signaling in the liver and the biliary tree
-
Häussinger D, Keitel V, Kubitz R, (eds), DeGruyter Publishing, Berlin:
-
Häussinger D, Reinehr R, Keitel V (2012) Bile acid signaling in the liver and the biliary tree. In: Häussinger D, Keitel V, Kubitz R (eds) Hepatobiliary transport in health and disease. DeGruyter Publishing, Berlin, pp 85–102
-
(2012)
Hepatobiliary transport in health and disease
, pp. 85-102
-
-
Häussinger, D.1
Reinehr, R.2
Keitel, V.3
|