Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 304, Issue 11, 2013, Pages

  Masyuk, Anatoliy I ^a   Huang, Bing Q ^a   Radtke, Brynn N ^a   Gajdos, Gabriella B ^a   Splinter, Patrick L ^a   Masyuk, Tatyana V ^a   Gradilone, Sergio A ^a   LaRusso, Nicholas F ^a  

^a Mayo Clinic   (United States)

Author keywords

Bile acid signaling; Cholangiocytes; G protein coupled bile acid receptor; Primary cilia; TGR5

Indexed keywords

BILE ACID; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; TGR5 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS MEMBRANE; CELL PROLIFERATION; CELLS; CELLULAR DISTRIBUTION; CHOLANGIOCYTE; CILIATED EPITHELIUM; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIVER POLYCYSTIC DISEASE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

BILE ACID SIGNALING; CHOLANGIOCYTES; G PROTEIN-COUPLED BILE ACID RECEPTOR; PRIMARY CILIA; TGR5;

ANIMALS; BILE ACIDS AND SALTS; BILE DUCTS, INTRAHEPATIC; CELL LINE; CELL MEMBRANE; CELL PROLIFERATION; CILIA; CYCLIC AMP; EPITHELIAL CELLS; EXOSOMES; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84878631549     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00383.2012     Document Type: Article

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