Bile acid feeding induces cholangiocyte proliferation and secretion: Evidence for bile acid-regulated ductal secretion

Gastroenterology

Volumn 116, Issue 1, 1999, Pages 179-186

  Alpini, G ^a   Glaser, S S ^a   Ueno, Y ^a   Rodgers, R ^a   Phinizy, J L ^a   Francis, H ^a   Baiocchi, L ^a   Holcomb, L A ^a   Caligiuri, A ^a   Lesage, G D ^a  

^a TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; BILE ACID; CYCLIC AMP; CYCLINE; DNA; HISTONE H3; SECRETIN; TAUROCHOLIC ACID; TAUROLITHOCHOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE DUCT; BILE FLOW; BILE SECRETION; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; HEPATITIS; IMMUNOHISTOCHEMISTRY; INTRAHEPATIC BILE DUCT; LIVER INJURY; MALE; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0032899948     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(99)70242-8     Document Type: Article

References (30)

1. G Alpini R Lenzi L Sarkozi N. Tavoloni Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules J Clin Invest 81 1988 569 578
2. G Alpini C Ulrich II J Phillips L Pham L Miller N. LaRusso Upregulation of secretin receptor gene expression in rat cholangiocytes after bile duct ligation Am J Physiol 266 1994 G922 G928
3. G LeSage S Glaser S Gubba WE Robertson JL Phinizy J Lasater R Rodgers G. Alpini Regrowth of the rat biliary tree after 70% partial hepatectomy is coupled to increased secretin-induced ductal bile secretion Gastroenterology 111 1996 1633 1644
4. G Alpini S Glaser W Robertson JL Phinizy R Rodgers A Caligiuri G. LeSage Bile acids stimulate proliferative and secretory events in large but not small cholangiocytes Am J Physiol 273 1997 G518 G529
5. KN Lazaridis L Pham P Tietz RA Marinelli P deGroen S Levine P Dawson NF. Larusso Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter J Clin Invest 100 1997 2714 2721
6. A Benedetti A Di Sario L Marucci G Svegliati-Baroni CD Schteingart H-T Ton-nu AF. Hofmann Carrier-mediated transport of conjugated bile acids across the basolateral membrane of biliary epithelial cells Am J Physiol 35 1997 G1416 G1424
7. D Gurantz AF. Hofmann Influence of bile acid structure on bile flow and biliary lipid secretion in the hamster Am J Physiol 247 1984 G736 G748
8. RH Palmer Z. Ruban Production of bile duct hyperplasia and gallstones by lithocholic acid J Clin Invest 45 1966 1255 1267
9. JR Spivey SF Bronk GJ. Gores Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium J Clin Invest 92 1993 17 24
10. T Patel SF Bronk GJ. Gores Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes J Clin Invest 94 1994 2183 2192
11. RE Poupon B Balkau E Eschwege R. Poupon A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis N Engl J Med 324 1991 1548 1554
12. +-dependent bile acid transporter in large but not small rat cholangiocytes Gastroenterology 113 1997 1734 1740
13. W Pandak Z Vlahcevic D Heuman K Redford J Chiang P. Hylemon Effects of different bile salts on steady-state mRNA levels and transcriptional activity of cholesterol 7alpha-hydroxylase Hepatology 19 1994 941 947
14. E Strange J Scheibner C Lutz H. Ditschuneit Feedback regulation of bile acid synthesis in the rat by dietary vs. intravenous cholate or taurocholate Hepatology 8 1988 879 886
15. B Davis J. Madri Type I and type III procollagen peptides during hepatic fibrinogenesis Am J Pathol 126 1987 G137 G147
16. S Glaser R Rodgers JL Phinizy W Robertson J Lasater A Caligiuri Z Tretjak G LeSage G. Alpini Gastrin inhibits secretin-induced ductal secretion by interaction with specific receptors on rat cholangiocytes Am J Physiol 273 1997 G1061 G1070
17. M Ishii B Vroman NF. LaRusso Isolation and morphological characterization of bile duct epithelial cells from normal rat liver Gastroenterology 97 1989 1236 1247
18. ER Weibel D. Gomez A principle for counting tissue structure on random sections Appl Physiol 17 1962 3443 3448
19. AM Rutemberg H Kim JW Fishbein JS Hanker HL Wasserkrug AM. Seligman Histochemical and ultrastructural demonstration of γ-glutamyl transpeptidase activity J Histochem Cytochem 17 1969 517 526
20. F Mashige N Tanaka A Maki S Kamei M. Yamanaka Direct spectrophotometry of total bile acids in serum Clin Chem 27 1981 1352 1356
21. A Cantafora A Di Biase D Alvaro M. Angelico An improved method for measuring the glycine and taurine conjugates of bile salts by high performance liquid chromatography with tauro-7-alpha-, 12 alpha, dihydroxy-5-beta-cholanic acid J Chromatogr 386 1987 367 370
22. K. Kitani The protective effect of hydrophilic bile acids on bile acid hepatoxicity in the rat Ital J Gastroenterol 27 1995 366 371
23. C Fischer N Cooper M Rothschild E. Mosbach Effect of dietary chenodeoxycholic acid and lithocholic acid in the rabbit Am J Dig Dis 19 1974 877 886
24. F Gratton A Weber B Tuchweber R Morazain C Roy I. Yousef Effect of chronic administration of taurolithocholate on bile formation and liver ultrastructure in the rat Liver 7 1987 130 137
25. M Barone A Francavilla L Polimeno E Ierardi D Romanelli P Berloco A Di Leo C. Panella Modulation of rat hepatocyte proliferation by bile salts in vitro and in vivo studies Hepatology 23 1996 1159 1166
26. H Shinozaki A Funakoshi K Miyasaka K. Kitani Stimulatory effect of ursodeoxycholate on pancreatic exocrine secretion in an in vitro study Pancreas 10 1995 246 250
27. +-dependent bile acid transporter on the cholangiocyte apical membrane regulates ductal reabsorption of bile acids and ductal bile secretion in bile duct ligated (BDL) rats (abstr) Hepatology 26 1997 A529
28. LG Fine JT Norman DA Kujubu A. Knecht Renal hypertrophy 2nd ed DW Seldin G Giebisch The kidney: physiology and pathophysiology. 1992 : Raven New York 3113 3133
29. G Alpini S Glaser JL Phinizy R Rodgers W Robertson A Caligiuri J Lasater Z Tretjak G. LeSage Bile acid depletion decreases cholangiocyte proliferative capacity and secretin-stimulated ductal bile secretion in bile duct ligated rats (abstr) Gastroenterology 112 1997 A1210
30. G Alpini S Glaser A Caligiuri J Phinizy R Rodgers H Francis W Robertson E Papa J Lasater G. LeSage Ursodeoxycholic acid feeding inhibits secretin-induced cholangiocyte secretory processes in bile duct ligated rats (abstr) Gastroenterology 114 1998 AL0016