Subducted and melanotic cells in advanced age-related macular degeneration are derived from retinal pigment epithelium

Investigative Ophthalmology and Visual Science

Volumn 56, Issue 5, 2015, Pages 3269-3278

  Zanzottera, Emma C ^a,b   Messinger, Jeffrey D ^a   Ach, Thomas ^a,c   Theodore Smith, R ^d   Curcio, Christine A ^a  

^a UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^d NEW YORK UNIVERSITY   (United States)

Author keywords

Age related macular degeneration; Apoptosis; Basal laminar deposits; Histology; Lipofuscin; Melanosomes; Migration; Retinal pigment epithelium; Transdifferentiation

Indexed keywords

LIPOFUSCIN; BIOLOGICAL MARKER;

AGE RELATED MACULAR DEGENERATION; ARTICLE; BASAL LAMINAR DEPOSIT; BRUCH MEMBRANE; ELECTRON MICROSCOPY; EYE DISEASE; FEMALE; GEOGRAPHIC ATROPHY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MELANOCYTE; MELANOSOME; PIGMENT EPITHELIUM; PRIORITY JOURNAL; SUBRETINAL NEOVASCULARIZATION; VERY ELDERLY; AGED; BASEMENT MEMBRANE; MACULAR DEGENERATION; METABOLISM; PATHOLOGY;

AGED; AGED, 80 AND OVER; BASEMENT MEMBRANE; BIOMARKERS; BRUCH MEMBRANE; CHOROIDAL NEOVASCULARIZATION; FEMALE; GEOGRAPHIC ATROPHY; HUMANS; LIPOFUSCIN; MACULAR DEGENERATION; MALE; MELANOSOMES; RETINAL PIGMENT EPITHELIUM;

EID: 84939811874     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.15-16432     Document Type: Article

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